Diane Krause (@Krauselab_Yale) profile picture

The Krause lab focuses on hematopoiesis, leukemia, and cell therapies including bone marrow transplantation and PSC-based treatment for hypoparathyroidism.

Yale Univ
Joined July 2009
Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)Photo by Diane Krause (@Krauselab_Yale)
Research led by @m_y_mayday uncovered how a mutant protein drives rare childhood leukemia #AMKL by hijacking RNA + Wnt signaling. Targeting these pathways with experimental inhibitors suppressed #leukemia growth. yalecancercenter.org/news-ar… @BloodPortfolio @Krauselab_Yale
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THE ECONOMY WILL FAIL WITH THE CUTS NIH FUNDING THAT ARE ABOUT TO PASS!!!!!!
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ASH Bridge Award direct cost floor was already raised to $500K/yr. Now the number of applications funded is dramatically increasing, with a rapid turn around...and a brand new additional cycle this year. @ASH_hematology
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🚨 @elonmusk, we need your attention! 🚨 A proposed 40% cut to the NIH budget will have catastrophic consequences for patients, biotech, academics, and most importantly, our economy. Here's why -->
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🚨 @elonmusk, we need your attention! 🚨 A proposed 40% cut to the NIH budget will have catastrophic consequences for patients, biotech, academics, and most importantly, our economy. Here's why -->
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.@rosadelauro @ChrisMurphyCT @SenBlumenthal Please continue to make medical research a priority by finalizing the FY2025 Labor, Health and Human Services, Education, and Related Agencies (Labor-HHS) spending bill with a robust investment in the NIH as soon as possible.
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Why would the NIH cancel study sections in response to an Exec order to discontinue communication with the public? these are private and confidential meetings. the public is not there.
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This is why my laboratory is working on developing a cell therapy for hypoparathyroidism.@HypoPARAassoc Andrea Ligler - post surgical hypoPARA patient youtu.be/rJTHU7DesEE?si=2KzI… via @YouTube
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excited to announce that the Yale Dept. of Cell Biology postdoc recruitment initiative, SUPR, is now official and posted on the department website: medicine.yale.edu/cellbio/po…
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Hello #sciencetwitter - consider checking out Bsky. @dianekrause.bsky.social.
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Proud of all authors of our paper showing RUNX1 is activated by CDK9 to promote megakaryocyte fate in primary human progenitors. Let us know what you think! @NKwonHem @EvrettT @mancuso_rubia @Yalelabmed @Yale_LabMed @RUNX1Research authors.elsevier.com/a/1j%7E…
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So proud of Garg_lab in @Yale_LabMed
Deeply honored for our laboratory to receive a NIH Director's New Innovator Award from @NIH_CommonFund. Delighted to see what we can learn about the origins of heterogeneity in cell systems over the coming years! #NIHHighRisk
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Come check out our poster 3300!!! #ISEH2024 @iu_cceh @CCEH_U24 Find out what the Cooperative Centers of Excellence in Hematology has to offer!
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From this article,scientificamerican.com/artic… "Project 2025, the sweeping right-wing blueprint for a new kind of U.S. presidency, would sabotage science-based policies that address climate change, the environment, abortion, health care access, technology and education."
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MARK YOUR CALENDARS! 📅✅Yale #LabMed & #Pathology invite you to our #PathologyOpenHouse. Join one of our virtual open houses featuring our Residency Program Leadership and residents @YalePathRes Tuesday, August 27th 6 PM - 7 PM or Sunday, September 8th 2 PM - 3 PM Registration QRC attached. PLEASE RETWEET @Yale_labmed & @Yalepathology – at New Haven, CT
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Very proud that our discovery that phophoserine RUNX1 promoted megakaryocyte (MK) fate specification in primary human MEP is out! @YaleCCEH @Yale_LabMed Work of many including the amazing @NKwonHem sciencedirect.com/science/ar…
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In primary human cells, phospho-serine RUNX1 increases w/ MK fate , and phosphomimetic RUNX1 promotes MK fate. And, we show that CDK9 is the primary kinase responsible for RUNX1 P'n - linking transcriptional elongation and RUNX1 activation in hematopoietic fate specification.
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