Transcription Factor Code in Odontoblast Differentiation Decoded 🧬!
In our new paper in JDR, we show that four transcriptional regulators (Sall1, Gsc, Etv4, and Nupr1) are sufficient to directly drive the differentiation of pluripotent stem cells into odontoblast-like cells. 🦷
...although the process is much more complex and interesting.
Check all the details in our recent paper, which is now open access!
journals.sagepub.com/doi/10.…
It was my pleasure to give a talk at this lovely event again - for the fourth time - as I have done since the very beginning of its existence (initiated by @MarcelaBuchtova 6 years ago in my city Brno, Czech republic ❤️ )!
The next exciting talk is held by Jan Křivánek @KrivanekLab of @MasarykUni who will teach us new insights into Mechanics and Mechanisms of Mouse Incisor Growth and Repair!
#developmentalbiology #dentalresearch #regeneration
Jan Krivanek retweeted
🇬🇧Researchers from @KrivanekLab at the Department of Histology and Embryology have succeeded in "programming" stem cells to transform into cells that form dental tissue. They directly intervened in the cells’ genome
Jan Krivanek retweeted
Květnová Research Breakfast s @KrivanekLab
U ☕️se diskutovalo o vědeckých poznatcích Honzy a jeho týmu i o tom, jak vědu komunikovat
May Research Breakfast with @KrivanekLab
At ☕️, we discussed the scientific findings of Honza and his team and how to communicate research
I just returned from Portland, Oregon from The Anatomy Connected @AnatomyOrg meeting, where I had an Invited lecture. Such an inspiring meeting! It exceeded all my expectations! Thanks for having me there! @Science_MEDMUNI
PhD positions in our team available from 9/2025! For more information please contact us. @Science_MEDMUNI @V4Sdb
Jan Krivanek retweeted
1/🚀 Excited to share RegVelo, our new computational model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇
biorxiv.org/content/10.1101/…
🥳 I am excited to share that we have received a new Grant from the Czech Science Foundation @GACR ! It will allow us to study NATURAL DENTAL HEALING which may open new doors in Regenerative Biologically-Based Dentistry of the future! Fascinating stuff ahead!
Replying to @Science_MEDMUNI
7⃣grants were supported by the 🇨🇿agency GAČR
For the 1st time, we received the Postdoc Individual Fellowship for Vladimír Svoboda
Congratulations to PIs
@KrivanekLab @masariklab, Zdeněk Andrysík, Zuzana Kadlecová, Stjepan Uldrijan and Petr Fojtík
Marcos G.L., PhD student from our team talks about his research at @EFEM_Europe in Bulgaria
...and gets the prize for the BEST TALK 🥳🫶 !
This happened after Josef, another PhD student from our team won last year.
I'm proud of you guys😎!
@Science_MEDMUNI
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Jan Krivanek retweeted
👋Gratulujeme Marcosovi G. Lopézovi k Ceně rektora @muni_cz pro vynikající studenty doktorských studijních programů🎖️
Marcos se pod vedením školitele @KrivanekLab v programu Biomedicínské vědy věnuje základním aspektům vývojové biologie a novým přístupům v regenerativní medicíně
Together with the labs of Igor Adameyko and Kaj Fried, we had an amazing lab retreat in our South Moravian region! Such a lovely reunion. I’m now full of inspiration👍🙂 ! @adameykolab
We love light sheet microscopy 🙂! I'm proud that our image ended up as a cover on Cell reports issue. Amazing paper of @AlcaSalas and the crew 🙂 !
Our new old school analog notice board. With amazing cover picture from our #lightsheet @zeiss_micro 🔬. Fantastic work of @AlcaSalas @KrivanekLab.
Jan Krivanek retweeted
We're thrilled to announce the selection of 24 exciting symposia for our upcoming Helsinki #EED2024 conference! 🧬🔬🐿️🐀🦜🐊🐠🦑🦟🪱🍀🦠 Happy holidays and see you all in Helsinki! More information here: tinyurl.com/EEDHelsinki Abstract submission details to follow in early 2024!
Jan Krivanek retweeted
3⃣our scientist became MUNI SCIENTIST 2023
📌Regina Demlová (Dpt. of Pharmacology) project CREATIC
📌Jan Křivánek (Dpt. of Histology and Embryology) publication in Science Advances
📌Radka Lordick Obermannová (Dpt. of Comprehensive Cancer Care) publication in Annals of Oncology
Huge congrats to our doctoral student Haneen Tuaima on getting the prestigious "PhD talent" award! Well deserved!🥳🥂
2⃣ our PhD candidates were awarded this year's Brno Ph.D. talent award by @JCMM_Brno
📌Ema Huščárová (supervisor @jarogumulec , Pathological Physiology)
📌Haneen Tuaiama (supervisor @KrivanekLab , Cell and Tissue Morphology)
Congratulations, and good luck with your future work👏
Jan Krivanek retweeted
Marcos Gonzales and Josef Lavicky from @KrivanekLab were invited speakers to represent our facility at Imaging Principles of Life conference at Hradec Kralove #CzechBioimaging #microscopy #facility 👋👋👋👋👋




























