Dr. Kshitiz Gupta Cancer Research Lab at the University of Connecticut Health Center. We focus on Cell-Cell Communication with a focus on Tumor Microenvironment
263 Farmington Avenue
Joined March 2021
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Our continued research connecting pregnancy and metastatic cancer was recently covered by Scientific American Magazine.
@sciam
#research #cancer #CancerResearch #biology #medicine #MedTwitter #biotech #STEM #StemEducation #ScienceTwitter
scientificamerican.com/artic…
Kshitiz Lab retweeted
These #cardiomyocytes are mature for their age!
The @KshitizLab at @UConn used cardiac mimetic matrix to generate cardiomyocytes with adult-like characteristics and model pathological #hypertrophy. 🫀
@CellReports paper: bit.ly/3QDbffI
Episode: bit.ly/3P8T8wN
Kshitiz Lab retweeted
And in the roundup:
1) Modeling polycystic kidney disease 🫘
@TTdevbio @USCStemCell
2) Generating mature myocytes ♥️
@KshitizLab @JunaidAfzal_etc
3) Tracking T cells in organoids 🔍
@_Hubrecht @NatureBiotech
4) MSCs in the aorta 🧫
@UNSWMedicine
📣 A new episode just dropped!
Dr. Jackie Damen from @STEMCELLTech talks about helping scientists conduct their experiments, systems for #DrugDiscovery, and opportunities in industry.
🔊 Listen now: bit.ly/3P8T8wN
Congratulations to @KshitizKz, Gunter Wagner, @YasirSuhail7, and the rest of the team members for such groundbreaking work and recognition.
#research #cancer #CancerResearch #biology #medicine #MedTwitter #biotech #STEM #StemEducation #ScienceTwitter
The cow in your body. The more cow (or if you prefer horses) like we are inside, the more it prevents cancer spread.
#Cancer #CancerResearch #animalscience #animals #metastasis #research #Biology #MedTwitter #MedEd #medicine #nature #cow #horse #science
mdpi.com/2072-6694/14/9/2197…
Metastasis is the leading cause of cancer-related deaths and enables cancer cells to compromise organ function by expanding in secondary sites.
@Sarah_E_Pierce @JeffreyGranja @WJGreenleaf @LabWinslow @RuiTang16 @HowardYChang
#cancer #research
Source: pubmed.ncbi.nlm.nih.gov/3434…
Scientists found that the tumor suppressor gene LKB1 is frequently inactivated and identify LKB1 as a master regulator of chromatin accessibility and pro-metastasis factor.
#ScienceTwitter #CancerResearch #MedTwitter #educational #stem #regeneration #health #laboratory #biotech
Drugs targeting advanced breast cancers associated with mutant ERα represent a major unmet medical need.
@SilvioGutkind
#stroma #tumor #evolutionarymedicine #systemsbiology #cancer #medicine #MedTwitter #researchpaper #science #health #data
source: nature.com/articles/s41467-0…
Developed LATS inhibitors that effectively suppress the expression of ESR1, providing new potential therapeutic targets for ER+ breast cancer, particularly those with hormone therapy-resistant ESR1 mutations.
#research #cancer #biology #science #STEM #STEMeducation #education
The authors delineated the mechanism of ESR1 transcriptional repression by the LATS-YAP-TEAD-VGLL3 axis.
#ScienceTwitter #CancerResearch #MedTwitter #educational #facts #study #stem #regeneration #health #laboratory #biotech #cancer #fibroblast #biology #nature #breastcancer
Tissue repair and cancer are linked.
@thecrick @IMalanchi @ScienceDaily
#stroma #fibroblast #cancerenvironment #tumor #evolutionarymedicine #systemsbiology #inflammation #cancer #medicine #MedTwitter #researchpaper #science #health #data
Source: sciencedaily.com/releases/20…
So an organ can be predisposed to get cancer by inflammation, or bad repair.
#ScienceTwitter #CancerResearch #MedTwitter #educational #facts #study #stem #regeneration #health #laboratory #evolutionarymedicine #cancer #fibroblast #inflammation #repair #tissuerepair
Scientists at Francis and Crick Institute found that the relationship between immune response and cancer is very complex. And it is their communication that can make cancer spread.
@thecrick @IMalanchi @ScienceDaily
#cancer #biology #technology #healthcare #ScienceTwitter
Our paper connecting pregnancy to cancer malignancy is out in PNAS.
The paper details how pregnancy has evolved in mammals with direct effect on cancer metastasis in humans.
pnas.org/content/119/6/e2111…