RNA biology of embrogenesis and disease #heart #ribosome #translational_control #RBP Faculty @goetheuni Alum:@salkinstitute @UcSandiego
Frankfurt, Germany
Joined June 2015
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Many conserved exons in the heart and brain utilize weak 5 ′ splice sites, yet they are accurately spliced. But how?
biorxiv.org/content/10.1101/…
bsky.app/profile/kurianlab.b…
Our department page has had a glow-up. New look, same obsession with heart and vascular science and RNA biology.
Sharper, cleaner, and much more clickable:
vrc-frankfurt.de
Design credits: Manoj Kurian
@goetheuni @CPI_ExStra
🙏 RT so we can attract good people
"Inaction teaches power; it can kill without consequence. The world you tolerate today is the world your children will inherit tomorrow."
Kurian Lab retweeted
Join our CTO Felipe Opazo @FelipeOpaz_o at #MBSJ2025 @MBSJ_official as he presents new super-resolution #multiplexing approaches powered by #SmartSecondaries.
🔬Discover flexible, scalable & precise multi-target imaging!
#Nanobody
#NanoPlex #SUMPAINT
#SuperResolution #Microscopy
Very thankful to our collabortors especially the labs of Michael Sattler, Arjun Ray, Dumbovic lab, and Christian Münch @MuenchLab
@goetheuni
@CPI_ExStra
@SCALE_Uni_FFM
And special thanks to
@jakub-zeman.bsky.social
who did the tough part of winding up the paper from our side. Digging out all old data and finishing up the last parts while rebuilding the lab
Kurian Lab retweeted
Sargent is a transformation- and cluster-free cell-type annotation method that operates at individual cell resolution by applying a scoring system to scRNA-seq data based on sets of marker genes associated with cell types.
github.com/nourin-nn/sargent… from my colleague Nima.
There is a lack of general terminology for translated regions that does not depend on the properties of their products or their sequence. Spearheaded by Pavel (Pasha) Baranov, this primer provides a unifying nomenclature for translation units: *Translon*
nature.com/articles/s41592-0…
Kurian Lab retweeted
Excited to have 3i Intelligent Imaging Innovations @3i_inc on board as a sponsor for #GEF25, celebrating 10 years of Expansion Microscopy.
Great to team up with cutting-edge imaging specialists as we look ahead.
🔗 rizzoli-lab.de/gef25/
Check this beauty from @incaRNAtolab
I am so incredibly excited to share our latest work, on the exploration of #RNA secondary structure ensembles and discovery of RNA regulatory structural switches in bacteria and human cells, out today in @NatureBiotech: nature.com/articles/s41587-0…. A short tread! (1/n)
Kurian Lab retweeted
One of the issues I had hoped to raise in the panel I was in was that misconduct is done by people, not because people are inherently bad, but because of the pressure to publish, the pressure of a demanding/bullying PI, from universities or even the government.
#FutureSciPub
Kurian Lab retweeted
Architectural RNAs: blueprints for functional membraneless organelle assembly: Trends in Genetics cell.com/trends/genetics/ful…
When sanity of Science is questioned without evidence by political decision makers, darkness looms over humanity....
If u can speak up, do so. If not, your children could LIVE The Handmaid's tale
npr.org/sections/shots-healt…
Kurian Lab retweeted
Unfortunately I have to delete the original thread (screenshot) because the "Pacmanoid" depiction of our discoveries - despite of course being completely original artwork - apparently could lead to copyright concerns. Full thread with different image: xitter.cf/jvveenvliet/status/191…
📢 Now in @CellStemCell! Our @teamstembryo
tour de force led by @RyanSavill4 & @VillarongaAlba @mpicbg
#gastruloids with a sweet tooth become more embryo-like: doi.org/10.1016/j.stem.2025.…
[reposting 🧵 since we were informed about copyright concerns regarding "Pacmanoid" in OP]
