PhD student. Working on epigenetic, embryonic development and FASD. Outdoor lover and chocolate addicted.
Joined February 2017
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Lisa-Marie Legault retweeted
Thank you @CR_CHUSJ for showcasing our lab's work, led by @LM_Legault , on the impact of early embryonic alcohol exposure on the placenta. @CIHR_IRSC @FRQS1 #epigenetics
Exposition de l’embryon à l’alcool en tout début de grossesse : des effets épigénétiques décelables dans le placenta selon une nouvelle étude par
@McGraw_Lab et coll. @CR_CHUSJ
tinyurl.com/4kx9vs3e
Latest paper is now out! This one might be even more special as it is my last PhD paper. Thanks to all the co-authors & @McGraw_Lab thanks for everything. I was lucky to spend my years as a graduate student in such a stimulating environment, with an amazing team and involved PI.
Paper alert! @LM_Legault et. al show that preimplantation alcohol exposure alters the #DNAmethylation and transcriptomic profiles in mouse placentas in a sex-specific manner, with DNA methylation being a robust predictive signature. bit.ly/4egTNcZ @CR_CHUSJ #FASD
Amazing project led by @eli__elder
Look at these figures 👌🏻
What is the long-term impact of loss of sustained DNA methylation maintenance by DNMT1 for molecular and cellular integrity of mouse embryonic stem cells?
Thrilled to share the lab’s newest preprint bit.ly/3WDALr5
Amazing effort from @eli__elder and team!
🧵1/11
Lisa-Marie Legault retweeted
Our newest publication in @BiologySexDiff , highlighting the importance of including sex-based analyses in epigenetic and transcriptional studies of the mouse placenta. Congrats @LM_Legault !! @CR_CHUSJ @UMontreal @NSERC_CRSNG bsd.biomedcentral.com/articl…
Lisa-Marie Legault retweeted
And that's a wrap on #CanEpi23! Thank you to everyone who attended and all of the sponsors for their continued support of our meeting. We've enjoyed seeing all of the amazing science and wonderful interactions that have taken place over the last 3 days.
See you all in 2024!
Lisa-Marie Legault retweeted
Explore our latest @Preprints_org review aiming to highlight O-GlcNAcylation's central role as an epigenetic mark, focusing on histone modifications. Collaboration with Thomas Dupas (new postdoc in our lab) and Prof. Benjamin Lauzier (@NantesUniv France ) preprints.org/manuscript/202…
Lisa-Marie Legault retweeted
Our News and Views ―Inheritance of epigenetic DNA marks studied in new mouse model― of the Takahashi et al. Cell 2023 paper on the Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice. Fun collaboration with @KimminsSarah nature.com/articles/d41586-0…
Lisa-Marie Legault retweeted
Happy to share our study in @FASEBorg ! Using a mouse model of pre-implantation alcohol exposure, we show that a maternal enriched diet for methyl-donor mitigates the negative impacts of alcohol exposure. #FASD bit.ly/3LcatGS
Awesome view after great science at #DOHaD2022 in Vancouver! First in person meeting since early 2020 and first one with my little human!
Lisa-Marie Legault retweeted
Don't miss out! The deadline for both early bird registration and travel award applications is midnight pacific time!!
The 8th Annual Conference on Epigenetics: ceehrc.ca/2022/
Travel Awards for Trainees: thisisepigenetics.ca/for-sci…
#CanEpi22 #IHEC2022 #ThisIsEpigenetics
Lisa-Marie Legault retweeted
Thank you Patrick Lagacé @kick1972 @le985fm
for the interview on #FASD and our study (PS: work done by great team of trainees @LM_Legault @KarineDoiron01 @MlanieBL1 @_alexlangford @LemieuxAnthony3 and collaborators M.Caron, @lamsciworld and D. Sinnett) pubmed.ncbi.nlm.nih.gov/3442…
Lisa-Marie Legault retweeted
En ce mois de la sensibilisation au trouble du spectre d'alcoolisation fœtale, une nouvelle étude du professeur @McGraw_Lab met en garde contre une forte consommation d’alcool dès la 1re semaine de grossesse.
➡️ bit.ly/39lg2P3
#Epigenetics #DNAmethylation #FASD
So happy about that paper!!
Happy to share the published open access version (with added data) of our pre-print paper from @LM_Legault and team! Find below tread on main results. clinicalepigeneticsjournal.b…
Lisa-Marie Legault retweeted
Check out our updated version of the paper!
Very excited to share our new work (@LM_Legault et al.) Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain #FASD #Epigenetics #DNAmethylation 1/ biorxiv.org/content/10.1101/…
Lisa-Marie Legault retweeted
Today, we launch a new initiative: This Is Epigenetics!—an effort to support Canadian epigenetic researchers and engage people across the country with this rapidly evolving and exciting field of study! Check it out: thisisepigenetics.ca #epigenetics #epigenomics #scicomm #kt
Lisa-Marie Legault retweeted
Very excited to share our new work (@LM_Legault et al.) Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain #FASD #Epigenetics #DNAmethylation 1/ biorxiv.org/content/10.1101/…
Lisa-Marie Legault retweeted
Paper is out! See the final version of our #preprint now published in @EpigeneticsJ : Developmental genome-wide DNA methylation asymmetry between mouse placenta and embryo. Thanks again to reviewers for thoughtful suggestions! tandfonline.com/doi/full/10.…
Developmental Genome-Wide DNA Methylation Asymmetry Between Mouse Placenta and Embryo biorxiv.org/cgi/content/shor… #bioRxiv
Lisa-Marie Legault retweeted
It’s International Day of Women and Girls in Science! To my sisters in science, know you have a champion and an ally. Let’s inspire the next generation to discover. Because more than ever, the world needs science; and science needs women. #WomenInScience
