@LabShih

Twitter of the Lab of Dr. Patrick Shih at UC Berkeley

 Berkeley, CA
nature.berkeley.edu/shih-lab
Joined May 2019
  • Tweets452
  • Following460
  • Followers1.2K
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ShihLab retweeted
Corinne Scown@cdscownJun 15
Nice UCB study on the human health impacts of deploying carbon capture and sequestration, now out in @naturesustainab! Check out the paper here: rdcu.be/fopCu
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ShihLab retweeted
Nature Biotechnology
@NatureBiotech25 Nov 2025
Multiplexed profiling of transcriptional regulators in plant cells go.nature.com/4pw5cL1
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Excited to share our lab’s first publication at UGA! PhD student Taden Welsh's new perspective highlights how plant + bacterial synthetic biology could enhance iron mobilization for food crop fortification.🌱🦠🧬 pubs.acs.org/doi/10.1021/acs…

Genetically Reprogramming Crops and Rhizobacteria for Nutritional Iron Biofortification

Abstract. Iron is a critical micronutrient for both plants and humans, yet its declining availability across agricultural systems threatens global food sec

pubs.acs.org
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Active learning enables discovery of transcriptional activators across fungal evolutionary space biorxiv.org/content/10.1101/… #biorxiv_genomic

Active learning enables discovery of transcriptional activators across fungal evolutionary space

Biological discovery and design are increasingly being guided by predictive models in place of costly experimentation. However, existing datasets are often biased by overrepresentation from model...

biorxiv.org
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Big news from Demirer lab: 4 research papers preprinted! Feedback welcomed: eCIS for plant protein delivery: tinyurl.com/mrx4d878 R2 for targeted insertion: tinyurl.com/5n73za6h Transient expression: tinyurl.com/38p2ud6w Chemotaxis assay: tinyurl.com/3nw9haes 👀⬇️
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A truly enabling new approach by Tara Lowensohn, @WillCody_12 and @Sattely_lab to probe plant genetics at scale. Single-gene-per-cell delivery coupled to an effective transcriptional selection system. Libraries in plants. biorxiv.org/content/10.1101/…
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Causes and consequences of experimental variation in Nicotiana benthamiana transient expression biorxiv.org/content/10.1101/… #biorxiv_plants
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Today the Shih Lab (@LabShih) presents ENTRAP-seq, a high-throughput assay for functional screening directly in plant cells.
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nature.com/articles/s41477-0…
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New OA Article: "Quantitative dissection of Agrobacterium T-DNA expression in single plant cells reveals density-dependent synergy and antagonism" rdcu.be/elJ5z News & Views: "Cooperation and antagonism in Agrobacterium-mediated transformation" rdcu.be/elJ5F
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In @ScienceAdvances, we report how small chemical modifications in the metabolism of ergosterol are needed for yeast membranes to phase seperate into ordered yet fluid domains science.org/doi/10.1126/scia… (1/n)

Structural dissection of ergosterol metabolism reveals a pathway optimized for membrane phase...

The metabolism of ergosterol shapes this lipid to allow the formation of fluid membrane domains in yeast cells.

science.org
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I am pleased to announce new research from the Shih Lab (@LabShih) published today in Nature Biotechnology on improving Agrobacterium-mediated transformation via binary vector copy number engineering (doi.org/10.1038/s41587-024-0…). 🧵A summary thread below🌿

Binary vector copy number engineering improves Agrobacterium-mediated transformation

Nature Biotechnology - Agrobacterium-mediated transformation of plants and fungi is enhanced by plasmid copy number variants.

nature.com
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ShihLab retweeted
Nature Biotechnology
@NatureBiotech4 Nov 2024
Binary vector copy number engineering improves Agrobacterium-mediated transformation go.nature.com/3CdewQS
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Congrats to our very own @allie_npearson for winning Best Poster Award at the @ ECI Biochemical and Molecular Engineering XXIII in Dublin, Ireland 🇮🇪 on her work uncovering the genetic basis of dicarboxylic acid metabolism. We are so proud! 💚🤍🧡
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The latest #cellfree natural products work from my lab! nature.com/articles/s41598-0…
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Congratulations to Professors @DanNomura, @_josephshapiro, and Patrick Shih (@LabShih) on being named 2024 @BakarFellows Spark Award recipients. The award provides funding, resources, and entrepreneurial mentorship to each recipient. bakarfellows.berkeley.edu/ba…

Bakar Fellows Program Announces 2024 Spark Award Recipients and New Partnership with the Academic...

The Bakar Fellows Program is excited to announce that eleven new Faculty Fellows have been selected as part of the 2024 Spark Award cohort. Among these recipients, two are being supported by the...

bakarfellows.berkeley.edu
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Fungi are key for feeding a growing population. Most current food strains were domesticated by our ancestors over 1000+ yrs. What does the next wave of domestication look like? We develop a synbio toolkit to program sensory appeal/nutrition of fungal meat! nature.com/articles/s41467-0…
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Want to make next-gen vaccine adjuvants using synthetic chemistry and biology? Apply to be a postdoctoral researcher in the Liu Lab at Scripps Research: recruiting2.ultipro.com/SCR1…
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We released a bacterial genome annotation pipeline, Beav, from the Weisberg Lab (@weisbergaj). GitHub: github.com/weisberglab/beav The preprint is also out: biorxiv.org/content/10.1101/… Please test it, use it, and report any bug. Let us know about any feature you like!

GitHub - weisberglab/beav: BEAV: Bacterial Element Annotation reVamped

BEAV: Bacterial Element Annotation reVamped. Contribute to weisberglab/beav development by creating an account on GitHub.

github.com
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For #MushroomMonday I'm thrilled to announce work I contributed to is published now in New Phytologist! It's all about life history strategies of the coolest mushroom, the death cap mushroom! Check it out here: ow.ly/s7Bo50Qn5xq

Death caps (Amanita phalloides) frequently establish from sexual spores, but individuals can grow...

Global change is reshaping Earth's biodiversity, but the changing distributions of nonpathogenic fungi remain largely undocumented, as do mechanisms enabling invasions. The ectomycorrhizal Amanita...

nph.onlinelibrary.wiley.com
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