@LabThoma

We are a structural biology lab located both at EPFL in Lausanne and at the Friedrich Miescher Institute in Basel.

 Lausanne, Switzerland
thomalab.org
Joined January 2019
  • Tweets254
  • Following345
  • Followers2.1K
27Media
Happy to share our preprint: "A Unified 3D Generative Model for Synthesizable Structure-Based Drug Design". Highlights, preprint, and code below: 🧵1/10
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Couldn’t recommend more highly!! @biomiko is a great scientist and mentor, as well as one of the niceaset friends I’ve ever met👍
Mikołaj Słabicki@biomiko10 Mar 2025
I am excited to announce the launch of the Slabicki Lab at the Krantz Family Center for Cancer Research within the Mass General Cancer Center and the Cancer Program at the Broad Institute of MIT and Harvard! 🔗 Learn more: slabicki-lab.org
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🚀 Calling early-career scientists! Apply for the 2025 ELISIR Scholar at EPFL. From outstanding PhD straight to group leader. Join an interdisciplinary research community to conduct independent research in any area of #lifesciences in Lausanne, CH 👉 go.epfl.ch/ELISIR
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Exciting day at the Novartis campus as the new FMI building opens its doors! Distinguished guests, including politicians, media & Novartis leaders, gathered to celebrate the exceptional collaboration between the FMI, @Novartis_CH & @UniBasel. Read more at: fmi.ch/news-events/articles/…

The FMI unveils state-of-the-art research facility on Novartis Campus in Basel

On August 23, 2024, the Friedrich Miescher Institute for Biomedical Research (FMI) celebrated the opening of its new, ultramodern research center on the Novartis Campus in the presence of some 100...

fmi.ch
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Designed complex protein topologies and enriched them with functionalities from membrane proteins, with high experimental success rates, leading to a de facto expansion of the functional soluble fold space @Nature @befcorreia nature.com/articles/s41586-0…
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📢📢📢 SAVE THE DATE! Join us for the @EMBO Workshop on "Ubiquitin and ubiquitin-like proteins in health and disease", 27th September – 1st October 2024, in Cavtat-Dubrovnik, Croatia. #emboubiquitin For more information and registration: meetings.embo.org/event/24-u… Please share 🙏
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Hey hey, if you like cell biology, virology, and enjoy Swiss chocolate. Join me at @FMIscience by applying for the lab manager position👇👇😃
FMI science@FMIscience16 Jan 2024
Please RT: Our incoming group leader @DahmaneSelma is hiring a lab manager to support day-to-day lab operations and help implement new techniques and protocols to investigate inflammasome antiviral responses. Apply by February 18 at bit.ly/DahmaneLabManager
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What an unforgettable week of celebrations! 🥳 I am beyond grateful to the @AAAS, @ScienceMagazine, @scilifelab, and the Knut and Alice Wallenberg Foundation for your support of early career scientists through the Science & @SciLifeLabPrize!
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Thomä Lab retweeted
Cell@CellCellPress12 Dec 2023
We are pleased to bring you the @CellCellPress paper of #FacesofCell Dr. Jacob Aguirre (@LabThoma), “Orphan quality control shapes network dynamics and gene expression” cell.com/cell/fulltext/S0092…
My goal is to solve more exciting structures of protein degradation complexes.

ALT My goal is to solve more exciting structures of protein degradation complexes.

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Thomä Lab retweeted
Radek Nowak@RPNowak3 Nov 2023
NEWS! I'm excited to share that I'm joining @IsbBonn @UniklinikBonn @UniBonn @ImmunoSens as a professor to start my LAB! We are open for business and #hiring for #postdoc #tech positions! #NewPI #MoveToGermany #UniBonn #TPD #InducedProximity Please share! nowak-lab.com

Nowak Lab | University of Bonn

The Nowak Lab at the Institute of Structural Biology, University of Bonn, studies targeted protein degradation and small molecule induced proximity to engineer the cellular interactome.

nowak-lab.com
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Thrilled to announce the lineup of speakers and open applications for our symposium to mark the opening of @UoDCeTPD! It promises to be a wonderful occasion to celebrate our field. Having so much fun to work in this with @val_spiteri @CharlCrowe @CraigMCrews Brenda and team!
Centre for Targeted Protein Degradation@UoDCeTPD2 Nov 2023
We're thrilled to announce our line up of confirmed speakers for our Symposium in May 2024! We invite you to apply via the link below. We hope you are as excited as we are for 3 days of science and Scottish fun! Apply-> buff.ly/40nLF45
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Thomä Lab retweeted
Beat Fierz@Beatfierz30 Oct 2023
Another exciting position @EPFL in Life Science Engineering, spanning the disciplines of: synthetic, systems and computational biology, cellular and tissue engineering, biomaterials, functional genomics, proteomics and metabolomics! Find the details here: epfl.ch/about/working/profes…
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Don’t miss out on attending the Keystone Targeted Protein Degradation and Proximity Therapeutics, January 21-24, 2024 🧬⛷️👩‍💻 Abstract deadline is October 26. Targeted Protein Degradation  lnkd.in/erkd5Yt4 Proximity Based Therapeutics lnkd.in/evkF59ga
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Join us tomorrow at 11 am EST for a seminar focusing on UBR5, one of this summer's "hottest" ligases. Featuring speakers @jonathanMtsai, Jacob Aguirre, @KevinGMark, and @DurgaKolla427. Ebert Lab, @LabThoma, @RapeLab danafarbertargetedproteindeg…
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To bid farewell to Nicolas Thomä and his group, we looked back at @LabThoma's work on ‘molecular glues’, which — by informing the development of molecules that target and destroy disease-causing proteins — may help researchers treat incurable conditions. fmi.ch/news-events/articles/…

Small molecules to treat big diseases

Despite leaving behind thousands of deformed infants, thalidomide — and newer drugs derived from it — have proved effective cancer treatments. Researchers in the group of Nicolas Thomä at the FMI...

fmi.ch
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I had an amazing time at the #EFMCASMC23 and #EFMCYMCS23 and I'm very humbled to have received the EFMC PhD Prize. Thank you to @EuroMedChem @YoungSciNet for this recognition and for putting up two fantastic events!
EFMC Young Scientists Network@YoungSciNet10 Sep 2023
🏆YSN PhD. Prize Award🏆 Congratulations again to @zkozicka for winning our PhD. Prize award and @MargaridaEspad1 the runner up. #EFMCYMCS23
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Check it out! A new @AnnualReviews of Pharmacology and Toxicology article on rules that govern rational design of molecular glue degraders. Read the article by @MonteRosaTx, @LabThoma, and Ridgeline: bit.ly/3qNH5yK
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Time to register for the @KeystoneSymp #KSUbiquitin24 meeting, joint with #KSAutophagy24 ! Abstract and scholarship deadline Aug. 30.
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Big news! In Spring 2024 I will join the fantastic @ISTAustria in Vienna as a TT Asst. Prof! Our group –the Chromatin Structure and Rhythms Lab -will use cryoEM (SPA & tomo) to study how the interplay between TFs & chromatin shapes the genome to control biological timekeeping.
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Thomä Lab retweeted
Ivan Đikić@iDikic215 Jul 2023
Merging #Ubiquitin biology, #Autophagy and diseases at @KeystoneSymp 🙄 Exciting program, new discoveries & focus on trainees, pre-sking season. Real joy working with @CWolberger @AnastasiaGHenry @BaehreckeLab 👍🫶 Application for abstracts and selected talks August 30 😊
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