Sarah Woolner's lab at the University of Manchester, UK. We investigate mechanical regulation of cell division in developing tissues.
University of Manchester
Joined February 2019
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We’re looking for a PhD student to join our team:
findaphd.com/phds/project/bb…
The localisation of the mitotic spindle orientation protein, NuMA, is highly dynamic and sensitive to tissue stretch. Frogs are also great for live imaging 🐸
Check out our preprint:
biorxiv.org/content/10.1101/…
Check out our new preprint on bioRxiv. We show that NuMA localisation is sensitive to tissue stretch and acts to fine-tune division orientation.
Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation biorxiv.org/content/10.1101/…
Woolner Lab retweeted
Baby you’re a fiiiiirework!!!
Explanted Xenopus neural crest cell, microtubules (green) and actin (magenta). Imaging in frogs rocks- this is done room temp, no incubation, no problem. 🐸🔬✨
By Micaela Lasser, Helen Willsey @goodfrognosis Lab
@zeiss_micro LSM980 fast airyscan
Woolner Lab retweeted
Now online at Bull. Math. Bio. doi.org/10.1007/s11538-024-0…
Relaxation and noise-driven oscillations in a model of mitotic spindle dynamics, with Dionn Hargreaves and @LabWoolner
arxiv.org/abs/2402.10638
Come join the Manchester Xenopus community: the Dorey lab are recruiting a Research Associate to study the response of neural progenitor cells to spinal cord injury.
jobs.manchester.ac.uk/Job/Jo…
Woolner Lab retweeted
We are thrilled to announce that our @wellcometrust application to establish a Discovery Research Platform for Cell-Matrix Biology @OfficialUoM was successful! 🎉 Here’s what to expect #cellmatrixbiology 👇 (thread)
Discovery research has near limitless potential, but researchers can be faced with barriers too substantial to overcome alone.
To address this, we are directing £73 million into eight new Discovery Research Platforms.
Learn more ⤵️
wellc.me/416bBjJ
ALT Michael Dunn, Director of Discovery Research at Wellcome, says: "By providing substantial support focused on specific research challenges, we have the potential to revolutionise fields of research."