ELambe

@Luna3150 @physiologyuoft used optophysiology to show that #CCK interneurons inhibit ventral hippocampus neurons tagged with #retrobead labelling from the nucleus accumbens. Great working with @jckimlab again!

Vental hippocampal #CCK interneurons gate contextual reward memory cell.com/iscience/fulltext/S… @iScience_CP We braved the hippocampus because of a great collaboration 🙂 Elegant work by Robin Nguyen from @jckimlab and Sanghavy Sivakumaran aka @Luna3150 from @LambeLab

CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer’s disease rdcu.be/dya6m @Transl_Psych #rosmap investigation by Jonas Rybnicek aka @Knedlajz2 of @LambeLab with amazing collaborators @neuronJoy and @DanielFelsky (1/5)

This tree: "It's still Autumn for me!" Gloriously sunny last day of November in #Toronto

#Psychedelics, #serotonin, and beyond: Neuroscience pioneer and wonderful mentor. Thanks @NatureNeuro Miss you, George! rdcu.be/drifk

Congratulations, Dr. Venkatesan (@Sridevi292) !!! @physiologyuoft @uoftmedicine

Excited to share a cool #nicotinic discovery by the new Dr @sridevi292 out today in @iScience_CP Fun collaboration with @neuronjoy Eric Turner @cth1997 Kevin Liu @physiologyuoft Chrna5 and lynx prototoxins identify acetylcholine super-responder sub... sciencedirect.com/science/ar…

Need to recover lost #nicotinic currents? It is possible even in the older brain with #xanomeline & #NS9283. Paper now @npp_journal Kudos to stellar graduate students @saigepower @sridevi292 @physiologyuoft Here's the link: rdcu.be/c3ij5

Congratulations @Sridevi292 on the rock-star Ph.D. defence yesterday! Your research identified the fast and protective actions of #Chrna5 at prefrontal #nicotinic synapses and discovered Chrna5+ #acetylcholine super-responders with #subplate identity.

What happens when Grin1 deficiency leaves neurons with too few NMDA receptors (NMDARs)? Turns out there is a selective loss of extrasynaptic NMDARs compromising dendritic plateaus. Adult genetic intervention can bring them back! NMDARs #beingextra biorxiv.org/content/10.1101/…