Laura Graham (@LauraGrahamMD) header
Laura Graham (@LauraGrahamMD) profile picture

GU medical oncologist & clinical trialist at CU Anschutz | Director, Clinical GU Research Program | Prostate cancer research | Endurance athlete

University of Colorado
Joined June 2026
Photo by Laura Graham (@LauraGrahamMD)Photo by Laura Graham (@LauraGrahamMD)Photo by Laura Graham (@LauraGrahamMD)
Laura Graham retweeted
Terrific data for pasritamig and JNJ-9401 at #SITC2026. Excellent presentation by @LauraGrahamMD. Honored to be part of this study and so grateful to the patients and team @columbiacancer @ColumbiaMed @nyphospital who make these important advances possible.
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Laura Graham retweeted
There’s still time to vote for ASCO nominating committee - good friend and great leader in oncology @PGrivasMDPhD is a candidate who would make great contributions asco.org/about-asco/asco-ove…
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Laura Graham retweeted
Happening now - ASCO elections! @montypal has worked tirelessly through ASCO committees and now as president of MOASC to accelerate progress in cancer research and treatment. View all candidates and bios and vote now! Asco.org/elections
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Thanks, Mark! Enjoyed presenting these first clinical data exploring tumor-targeted CD28 costimulation alongside CD3 directed T cell engagement. Grateful for the collaborative effort from the J&J team, investigators, and especially the patients who made this research possible!
At #ESMO26 we introduced a new word, #RIPTAC, JNJ-6143. Introducing another innovation presented @sitcancer yesterday! FIH Investigational combo of Pasritamig our @JNJInnovMed KLK2xCD3 T-cell agent + our PSMA x CD28 co-stim JNJ-9401. Signal 1 & signal 2 together! #MyCompany
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Dual-antigen T-cell engagement demonstrates encouraging clinical activity in advanced prostate cancer. At #SITC26, Laura Graham, MD of @CUDeptMedicine presents phase 1 results showing substantial PSA reductions and a manageable safety profile with combined KLK2 and PSMA targeting. #MoffittSITC26
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Thank you @sitcancer for the opportunity to share our work at #SITC26! It was a privilege to present these exciting early data and be part of such a fantastic meeting. Grateful to all the patients and collaborators who made this research possible! @drmnstein @CUCancerCenter
Thanks @LauraGrahamMD for a great presentation at #SITC26. Groundbreaking research is always the case at a @sitcancer Annual Meeting!
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Excited to share our first-in-human #SITC2026 data combining pasritamig (KLK2×CD3) with JNJ-9401 (PSMA×CD28) in #mCRPC! At the recommended regimen (n=15): 73% PSA50 47% PSA90 27% undetectable PSA Promising early evidence for dual-antigen targeting with CD28 costimulation
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Encouraging safety at the recommended regimen: no grade ≥3 treatment-related AEs; 20% CRS, all grade 1. Grateful to the patients, investigators, and study team who made this work possible! Excited to see this approach move forward in phase 3. #SITC2026
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Grateful to @drmnstein for his mentorship, collaboration, and leadership throughout this study. A privilege to work with such an outstanding team and help bring these exciting data to SITC!
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Great to speak with @OncLive about our #SITC2026 data combining KLK2×CD3 T-cell engagement with PSMA×CD28 costimulation in #mCRPC. Encouraging early results with deep, durable PSA responses and favorable safety profile. Excited about the potential of this approach!
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Great chatting with @OncLive about our upcoming #SITC26 presentation! Excited to share our first-in-human phase 1 results combining PSMA×CD28 costimulation with KLK2×CD3 T-cell engagement in #mCRPC. Looking forward to tomorrow's presentation!
Thank you to @LauraGrahamMD of @CUCancerCenter for stopping by to discuss her @sitcancer presentation on phase 1 data for the PSMAxCD28 T-cell engager JNJ-87189401 plus pasritamig in mCRPC. Stay tuned for her presentation on Saturday at #SITC26!
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I’ll be presenting our late-breaking phase 1 results of JNJ-87189401 (PSMA×CD28) + pasritamig (KLK2×CD3) at #SITC26. Nov 7 | 1:45 p.m. MST Abstract #1175 | Looking forward to connecting! sitcancer.org/2026/schedule/… #ProstateCancer #Immunotherapy
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Grateful to receive the 2026 Quintin Family Foundation–PCF Young Investigator Award, supporting our T-REX research in advanced prostate cancer. Thank you to PCF the Quintin Family Foundation, and my mentors Thomas Flaig, Lawrence Fong, and Mark Stein! @PCFnews #ProstateCancer
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