Potential future treatments by targeting SLC transporter regulatory hinges to revive activity, revealed using a #Sybody enabler. Congrats to the Geertsma & Seeger labs for great work in @Nature. #StandWithUkraine
#biotechnology #pharmacology #antibody
nature.com/articles/s41467-0…
Linkster Therapeutics retweeted
Understanding the smallest elevators in the world: Researchers in the group of Eric Geertsma @inverted_repeat @mpicbg discover new function of overlooked structural element in the membrane transport protein family. Publication in @NatureComms Full news: mpi-cbg.de/news-outreach/new…
Linkster Therapeutics retweeted
The fall of #Avdijivka and the assassination of #Navalny are not victories of the RUS regime, but just another monument of their destructive path in history.
Linkster Therapeutics retweeted
Learn how a mycobacterial MFS transporter extracts hydrophobic triacylglycerides from the membrane and channels then into a periplasmic lipoprotein🤩Our story on the fascinating duo of Rv1410 and LprG is out now in @NatureComms 🥂🙌
nature.com/articles/s41467-0…
#mycobacteria #CryoEM
Linkster Therapeutics retweeted
And here is the finalised paper nature.com/articles/s41594-0…
again, super work from @oxkawaka , Dr Jo Parker & Dr Gabriel Kuteyi - go team!
Linkster Therapeutics retweeted
We determined the structures of human UCP1 in apo, ATP-bound, and DNP-bound states. (nature.com/articles/s41586-0…) Congratulations to Yunlu on another two-author paper!
Linkster Therapeutics retweeted
Also check out the News & Views on this paper by Parjit Kaur: nature.com/articles/s41589-0…
Linkster Therapeutics retweeted
Check out this nicely written News & Views article by Parjit Kaur about our paper!
nature.com/articles/s41589-0…
Linkster Therapeutics retweeted
Proud to see our DMS paper out in @nchembio after going through a productive review process🥳EfrCD's drug efflux activity profile determined for >1400 single variants. Identified single mutations that convert the exporter into a drug-specific ABC importer! nature.com/articles/s41589-0…
Watching proteins move in living cells: unraveling the complexity of multidrug resistance ABC transporters in @ScienceMagazine. Congrats to Bordignon, Moeller, Schäfer & Seeger labs.#sybody #peace #peaceforukraine
#biotechnology #pharmacology #antibody
science.org/doi/10.1126/scia…
Puzzle piece in metabolic diseases: #sybody technology contributes to first steps of a molecular understanding of cystinosis reported in @NatureComms. Congratulations to the Newstead Lab. #peace #peaceforukraine
#biotechnology #pharmacology #antibody
nature.com/articles/s41467-0…
Linkster Therapeutics retweeted
Great to see Mark's paper out rdcu.be/cTQje - The structural basis for cystine transport via cystinosin! Further insights into lysosomal transport and evolution of the PQ-loop family! Congrats to Sacha, Kamel and Jo with
@ProfKalium
providing ePhys support!
Linkster Therapeutics retweeted
Happy official news of Azadeh's grant from @lundbeckfonden to start her own group @uni_copenhagen - so much to thank you for after fantastic years and results in the lab @dandrite @MolBiolAU @NordicEMBL @EMBLHamburg and working also with @Roche @LinksterTx @seegerlab
Linkster Therapeutics retweeted
Battling bacteria: #sybody molecules prove lateral LPS transporter openings relevant to disease in @NatureComms. Congratulations to @leadxpro, @LabStahlberg & @seegerlab. Linkster appeals to #Peace & #PeaceForUkraine
#biotechnology #pharmacology #antibody
nature.com/articles/s41467-0…
Battling bacteria: #sybody molecules prove lateral LPS transporter openings relevant to disease in @NatureComms. Congratulations to @leadxpro, @LabStahlberg & @seegerlab. Linkster appeals to #Peace & #PeaceForUkraine
#biotechnology #pharmacology #antibody
nature.com/articles/s41467-0…
Linkster Therapeutics retweeted
Pathogen inhibition by #sybody molecules: exciting insights into how a S.pneumoniae transporter contributes to virulence. Congratulations @perezlab & @seegerlab, @biozentrum. Linkster appeals to #peace !
#biotechnology #pharmacology #antibodydiscovery science.org/doi/10.1126/scia…
Linkster Therapeutics retweeted
Ultra-fast #sybody platform generates SARS-Cov-2 neutralizing biparatopics April 18th 2020 in @biorxivpreprint, now @emboreports. Congratulations to PPlattet, @CPaulino_ & @seegerlab. Linkster appeals to #peace!
#biotechnology #pharmacology #antibody
xitter.cf/seegerlab/status/15008…
📢Our rapid response to the COVID-19 pandemic finally in peer-reviewed form @emboreports in collaboration with Philippe Plattet, @CPaulino_ @MembraneEnzymo1 🥳
„Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance“
doi.org/10.15252/embr.202154…
Ultra-fast #sybody platform generates SARS-Cov-2 neutralizing biparatopics April 18th 2020 in @biorxivpreprint, now @emboreports. Congratulations to PPlattet, @CPaulino_ & @seegerlab. Linkster appeals to #peace!
#biotechnology #pharmacology #antibody
xitter.cf/seegerlab/status/15008…
📢Our rapid response to the COVID-19 pandemic finally in peer-reviewed form @emboreports in collaboration with Philippe Plattet, @CPaulino_ @MembraneEnzymo1 🥳
„Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance“
doi.org/10.15252/embr.202154…
Linkster Therapeutics retweeted
📢Our rapid response to the COVID-19 pandemic finally in peer-reviewed form @emboreports in collaboration with Philippe Plattet, @CPaulino_ @MembraneEnzymo1 🥳
„Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance“
doi.org/10.15252/embr.202154…
Pathogen inhibition by #sybody molecules: exciting insights into how a S.pneumoniae transporter contributes to virulence. Congratulations @perezlab & @seegerlab, @biozentrum. Linkster appeals to #peace !
#biotechnology #pharmacology #antibodydiscovery science.org/doi/10.1126/scia…












