
Daily news and insights on research, investments and technologies that extend life and improve the quality of that extended life. #Longevity
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Joined December 2018
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Nature Biotechnology paper offers a better way to judge models that predict gene effects. Shift plans to use it to hunt for aging targets.
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#longevity #geroscience #NatureBiotechnology #geneeffects #aging
Insilico Medicine nominates ISM9546, an oral VAV1 degrader designed with generative AI, as a preclinical candidate for autoimmune disease.
vist.ly/5pghr
#longevity #geroscience #InsilicoMedicine #ISM9546 #autoimmunedisease
KAUST and Oxford researchers used a transistor-based sensor to read three forms of alpha-synuclein, reaching 90.9% accuracy in a small study.
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#longevity #geroscience #KAUST #Oxford #alphasynuclein
Rona Therapeutics grants Roche worldwide rights to an ALK7-silencing candidate, with up to $1.06b in further milestones on the table.
vist.ly/5pg62
#longevity #RonaTherapeutics #Roche #ALK7 #biotech
Intrinsic capacity isn’t simply fitness, independence or being disease-free.
It spans cognition, locomotion, psychological and sensory capacity, and vitality, but there’s no universally accepted composite score yet.
#longevity #geroscience #intrinsiccapacity
An up to $28.3 million ARPA-H award aims to stretch Bexorg’s human brain platform from 24 hours to two weeks.
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#longevity #geroscience #ARPAH #Bexorg #brainresearch
German biotech MODAG won for pairing a CE-marked diagnostic with a drug candidate that targets the same protein.
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#longevity #geroscience #MODAG #biotech #diagnostics
Adjusting for how advanced patients’ disease was at the start lifts the Phase 2 result. The method was added after the trial began.
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#longevity #geroscience #Phase2 #clinicaltrial #clinicalresearch
Cala Health’s kIQ Plus now offers three stimulation modes and a calibration before each use, and it’s available across the US.
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#longevity #CalaHealth #kIQPlus #stimulation #digitalhealth
Buck Institute’s Eric Verdin joins clinic leaders to tackle the ‘luxury diagnostic’ trap and the push for standardized care.
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#longevity #geroscience #BuckInstitute #EricVerdin #standardizedcare
BodySpec’s new storefront targets muscle loss from GLP-1 weight loss drugs, with scans said to take about 12 minutes.
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#longevity #bodyspec #muscleloss #glp1 #weightloss
VectorY is growing PIONEER-ALS from 12 to 36 participants to test VTx-002, an antibody therapy aimed at the protein TDP-43.
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#longevity #geroscience #vectory #pioneerals #vtx002
A quick digital memory test and a lab assay for brain disease are teaming up to flag neurodegeneration earlier.
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#longevity #geroscience #memory #braindisease #neurodegeneration
A Censuswide survey commissioned by PortionIQ finds confidence is lower among longer-term users, though it’s a snapshot from one brand.
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#longevity #censuswide #portioniq #survey #confidence
Forget the diagnosis count. The researcher who helped the WHO reframe aging says function, not disease, is the better yardstick.
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#longevity #geroscience #aging #function #disease
Jupiter Neurosciences also hired an adviser to explore a sale or licensing of its assets while the 30-person trial gets underway.
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#longevity #jupiterneurosciences #trial #licensing #assets
The whole-body scan company is launching a research network with 50+ institutions. Early findings come with some big open questions.
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#longevity #research #network #institutions #findings
The company added hormone therapy to its platform and released IBS results from nearly 16,000 members, with caveats attached.
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#longevity #hormonetherapy #ibs #results #members
Monte Rosa’s NEK7-targeting drug pulled several heart-risk biomarkers toward healthy levels in 108 people with obesity.
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#longevity #geroscience #nek7 #biomarkers #obesity
All three Phase 3 trials of the weekly shot ribupatide have finished enrolling, and the head-to-head against semaglutide is the one to watch.
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#longevity #ribupatide #semaglutide #phase3 #trials



















