PI of the INIMAC - Innate Immune Activation Lab - with a focus on innate immune cells and mechanisms leading to their activation. Opinions expressed are my own!
Vienna/Austria
Joined March 2012
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Today a milestone in the establishment of a line-up of in vitro models for #precisionmedicine was reached. In a joint effort with the team of M. Bergmann @MedUni_Wien we published the first out of several papers in @jitcancer today: bit.ly/3YRbsTh 1/n
Matthias Farlik retweeted
Honored to have both studies featured in a @NatImmunol News & Views piece titled "The EMPROR’s new groove" by Karina Nance & Helen Goodridge! (4/5)
nature.com/articles/s41590-0…
Matthias Farlik retweeted
Publication 2: Looking for EMPROR cells during development, we found a unique, extraembryonic hematopoietic niche at the maternal-fetal interface (MIXER tissue), which harbors progenitors (eEMPROR cells), completely separate from the yolk sac. (3/5)
nature.com/articles/s41590-0…
Matthias Farlik retweeted
Publication 1: We identified a previously unrecognized CD4-lineage erythro-myeloid progenitor (EMPROR cells) in adult bone marrow.
These cells provide an alternative pathway for tissue-resident macrophage generation (2/5)
nature.com/articles/s41590-0…
Matthias Farlik retweeted
Thrilled to share that our team’s latest research has been published back-to-back in @NatImmunol! 🔬👇
These two companion papers reveal a fundamental shift in our understanding of macrophage origins across embryonic development and adult life. 🧵 (1/5)
Matthias Farlik retweeted
Es ist weiterhin surreal, das eigene Traktat im Buchhandel präsentiert zu sehen.
Es freut mich, dass es offenbar ganz gut ankommt, hoffentlich mit schönem Endergebnis für CS Nordlicht der @CaritasSocialis.
Matthias Farlik retweeted
Announced by the ERC today (really bad news for science!!! It starts in Europe but will affect everybody) Because the REVIEWING LOAD is so bad, if your application fails you may need to wait mulitple years (>3?!?) until you can submit again!
The ERC is the lifeline of the leading labs in Europe, so many research programs will be terminated (just no other sources to compensate).
The letter from the ERC says “the only way is to reduce applications” (highlighted in the picture below) No!!!
It's the wrong direction. Use AI to assist review. It’s not perfect (yet), but it allows more proposals to be evaluated, and it could support, not replace, human reviewers.
Matthias Farlik retweeted
Excited to share that my main thesis work is now published in @NatureGenet! We built a comprehensive map of human skin and how its organized within the tissue and across the body. Full paper & tweetorial below! @MSHSDerm @andrewlji @GradSchoolSinai
nature.com/articles/s41588-0…
Very proud to be recognized with the Paul Langerhans Award by the ADF this year! This is, after all, a symbol of successful teamwork over the past years-the outcome of collaborations with so many people in my network I do not even start mentioning them-I would for sure forget one
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I'm looking forward to the next projects ahead! #macrophages rock!
@MedUni_Wien @CeMM_News @BockLab
Finally, a big thank you to my family- without their support many things would not be possible!
meduniwien.ac.at/web/en/abou…
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Matthias Farlik retweeted
Ein Grundproblem bei ME/CFS ist ja, dass nicht betroffenen Menschen (auch im medizinischen Bereich) oft jeglicher Vorstellungsrahmen bezüglich der Drastik fehlt.
Diese Folge der Dunkelkammer trägt hoffentlich zum besseren Verstehen bei.
dunkelkammer.simplecast.com/…
Matthias Farlik retweeted
Hätte nie gedacht, dass ich mal einen Artikel der @tazgezwitscher teile, aber vielen Dank, dass hier Aufmerksamkeit auf ein so erschütterndes und doch wichtiges Thema gelenkt wird
taz.de/Long-Covid-und-Selbst…
Matthias Farlik retweeted
Es tut sich was ! Neue Anlaufstelle : Wie Patienten mit Long Covid in der Steiermark versorgt werden sollen kleinezeitung.at/lebensart/g…
Matthias Farlik retweeted
Es freut mich echt, dass die ME/CFS-Folge des Dunkelkammer-Podcast so oft gehört/geteilt wird (zumindest auf @SpotifyDE)!
dunkelkammer.simplecast.com/…
Matthias Farlik retweeted
Manche Leute sagen, es braucht keine Versorgung für Long Covid.
Dass Geld für Forschung eine Fehlverteilung von Mitteln sei.
Dass Prävention nichts bringt.
Wäre spannend, diese Meinungen in den Kontext der in diesem Artikel errechneten Kosten zu setzen.
nature.com/articles/s41533-0…
Matthias Farlik retweeted
Interessanter Podcast ... Reinhören lohnt sich
Fantastische Aktion! Verstärkt durch den großartigen @neurostingl und unsere Folge in @dunkelkammerschafft Wissen podcasts.apple.com/at/podcas…
Es gibt sie - die Menschen, die Realitäten nicht verkennen. Für eine Zukunft - Seite an Seite!
Matthias Farlik retweeted
Im Podcast "Die Dunkelkammer" durfte ich mit @MFarlik, @edithmeinhart und Michael Nikbakhsh über ME/CFS sprechen.
Falls wer am Wochenende mal eine freie Stunde findet ;)
dunkelkammer.simplecast.com/…
Congrats! Well done!
Just a week or so after the publication of his latest paper, Mohamed successfully completed his PhD yesterday! Congratulations, Dr. Shoeb! @shoeb_mo92
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Matthias Farlik retweeted
🔬 New in Communications Biology: Researchers from @StAnna_CCRI & @MedUni_Wien developed a stem cell model to study an aggressive pediatric AML subtype (CBFA2T3::GLIS2). Findings reveal 2 ways the oncogene disrupts blood formation:
📄 nature.com/articles/s42003-0…
Matthias Farlik retweeted
🧬How do #macrophages respond so quickly to pathogens?
A new study by CeMM & @MedUni_Wien researchers (@BockLab & @MFarlik), reveals key regulators of immune responses using gene editing & machine learning.
➡️ More info: bit.ly/40p5ABe
🔗 Study: bit.ly/4lwEAIm
Finally - an amazing collaborative project comes to a fruitful end with this beautiful publication! Great collaboration with my former mentor @BockLab ! A first step into using CROP-seq to understand macrophage differentiation and function!
🛡️How do macrophages tailor their defenses to different pathogens? Our new paper in @CellSystems combines dense multi-omics time series with high‐content CRISPR screens (CROP-seq) to map the regulatory landscape underlying macrophage immune responses. #Immunity #Screening (1/9)
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