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Ever wondered if nuclear pore architecture and function changes during germ cell differentiation? In human spermatogenesis it does, and radically!!
Check out our first lab preprint @AliaCSantos et al! biorxiv.org/content/10.1101/…
@PiotrKolata1 @AlisterBurt @TDendooven @MRC_LMB
Matteo Allegretti retweeted
🎉 Finally out! 🎉 Thrilled to share our work on the evolution, structure and membrane remodeling of Asgard ESCRT-III proteins! Congrats to all of our wonderful authors and collaborators 😍
Happy to share the final format of our paper on Asgard ESCRT-III and the evolution of this protein family in eukaryotes!
science.org/doi/10.1126/scia…
Matteo Allegretti retweeted
🚨 New article alert! 🚨
I wrote an article in @Nature about how anyone in a well-resourced lab can implement to democratise scientific resources and training worldwide. 🌍🧪
👉 nature.com/articles/d41586-0…
@Cambridge_Uni @MedCambridge @CaiusCollege @MRC_LMB
Matteo Allegretti retweeted
I have two job adverts open at the minute:
- A PhD position on fast MLIPs for biomolecules (www2.mrc-lmb.cam.ac.uk/stude…)
- A postdoc position on developing a universal molecular mechanics force field (nature.com/naturecareers/job…)
Feel free to get in touch with questions.
Matteo Allegretti retweeted
Replying to @AdrianoAguzzi
How about adding something like this to the author contribution section ?
"The authors agree that equally contributing authors appear in a random order and may swap their order. The 'equal contribution' designation shall remain intact and will not be removed."
This fascinating journey through sperm cell differentiation would not have been possible without the great collaboration with David Barford lab, @TomHale1040915, EM facility @gcannonii, and LM facility! Enjoy the read!!
Matteo Allegretti retweeted
Thanks to @royalsociety and @MRC_LMB, @lab_baum and I are looking for a student to develop the next generation of fluorescent proteins for live and super-resolution imaging, as part of the LMB's four-year PhD programme.
www2.mrc-lmb.cam.ac.uk/stude…
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Matteo Allegretti retweeted
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Matteo Allegretti retweeted
Thank you everyone for everything peripheral: Lamins, LADs, NPCs, LINC comp, laminopathies, peripheral chromatin et al! Great 10th NECO meeting @Bruneluni @Co_Biologists @BiochemSoc @abcam @Nufediaz @PaolaVagnarelli @Frances91557638 @adambyron @MatteoAll @mankie06 @CenGEM_Brunel
Matteo Allegretti retweeted
Check out JP’s virtual lift-out experiment that made it on the cover of Nature Methods!
Our September issue is live! 🎉
nature.com/nmeth/volumes/21/…
On the cover, the serial lift-out approach enables enhanced lamella preparation for cryo-ET. Artwork by Jürgen Plitzko. Paper here: nature.com/articles/s41592-0…
Matteo Allegretti retweeted
Come and join this amazing group of scientists to work at the cutting edge of structural biology of telomeric complexes. The LMB is a highly collaborative place. Please share!
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Matteo Allegretti retweeted
Over the moon about this work! 🤩
Sam @Samlacey combines cryo-EM, #teamtomo magic, #AlphaFold, and structural proteomics (with Andrea Graziadei) to reveal the molecular structure of retrograde IFT. Massive breakthrough by an incredible talented young scientist. Bravo Sam! 👍 🚂
Our paper looking at the structure of retrograde IFT trains is out now! Have a look at the link, or see some of the headlines in this video:
cell.com/cell/fulltext/S0092…
Join our fantastic EM facility team!All latest high end instrumentation available!
Would you like to work in the MRC-LMB EM facility?
mrc.tal.net/vx/mobile-0/appc…





















