https://xitter.cf/t.co/7pv43ExVHN Read about our new forensic metascience work at https://xitter.cf/t.co/Szi6Rbvokd Founder and Director: @moreisdifferent.
Boston, MA
Joined February 2021
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The Metascience Observatory retweeted
PSA for DC-area folks -- I'll be speaking Mon Nov 9th in DC about "Forensic Metascience for Policymakers: How AI Can Clean Up the Scientific Record"
Thank you @monsieurwagner for hosting! RSVP here:
luma.com/d2tvndzh
The Metascience Observatory retweeted
Today I'm posting a new video to my YouTube Channel. Persistent misnaming of 17-OHPC as "progesterone" in medical literature lead to pregnant women receiving the wrong drug through compounding pharmacies: youtu.be/I1C9aDfLH-U
The Metascience Observatory retweeted
New paper: "AI Article Reviews Dominate Human Peer Reviews at Their Best: Evidence and Policy Choices" See: GaryKing.org/peerless. with Steven Worthington. Comments welcome!
The Metascience Observatory retweeted
Derek Lowe mentioned my preprint in his "In the Pipeline" series which is very cool - big fan of his writing! science.org/content/blog-pos…
The Metascience Observatory retweeted
I recorded a little video this morning explaining the fetchpdf Python package I've been working on. One of the cool things I learned is many publishers offer XML (JATS) even if they don't make available a PDF (bc paywalls). With fetchpdf you can get the xml and convert to PDF!
The Metascience Observatory retweeted
Today I am sharing a new preprint and accompanying blog post. Hundreds of published papers include impossible western blots showing protein expression in cell lines that have deleted or mutated genes. These clumsy mistakes are widespread and repeated by LLMs.
The Metascience Observatory retweeted
Cell Press investigating editor-in-chief accused of soliciting bribes from authors.
scmp.com/news/china/science/…
The Metascience Observatory retweeted
Dr. Willy Chertman of @HHSgov joins the Science: A New Golden Age Summit to discuss metascience and the process of improving scientific policy in the federal government.
Full remarks:
The Metascience Observatory retweeted
This is a big one - Opus 5.5's explainer for the 2026 Nobel Prize in Physiology or Medicine 👀
I had it do a deep dive into the history of optogenetics. The video covers the contributions of Boyden, Pan, Deisseroth, Nagel, Hegemann, Bamberg, Miesenböck, Zhang, and 15 others..
The Metascience Observatory retweeted
My full fireside conversation with @patrickc at the Science: A New Golden Age Summit.
We discussed building new institutions for discovery, accelerating scientific progress, and how America can move faster on the hardest scientific challenges.
The Metascience Observatory retweeted
Very exciting to see what @WillyInTheWorld has been up to @ HHS. Operation Trailblazer is a new initiative to make the US the #1 place in the world for clinical trials. Right now many trials are being moved overseas due to lower cost and better government support (faster, easier)
We can double the pace of scientific discovery.
Jay Bhattacharya is backing young investigators, accelerating rare disease research, and harnessing SI to transform biomedical discovery.
Willy Chertman is cutting research bureaucracy and modernizing clinical trials through Operation Trialblazer.
A new golden age of science.
@NIHDirector_Jay @DrJBhattacharya @willyintheworld @HHSGov
The Metascience Observatory retweeted
I had Claude create an explainer for the 2026 Nobel Prize in Chemistry 😍
The Metascience Observatory retweeted
I worry that academic fraud might be far more widespread than anyone can tell. It took 24 years to catch this case of likely fraud, and it was discovered only because the original data were available *and* because it was so obvious that certain rows had been copied elsewhere.
Imagine what people could get away with if only they were a little more clever in creating a few fake rows of data . . .
An influential paper by Ariely & Wertenbroch (2002) reported two studies with tampered data.
Post 1 of 2.
datacolada.org/138
The Metascience Observatory retweeted
Part 2 just dropped. Again, while there were warning signs in the paper, the smoking gun was in the raw data. How much fraud are we missing because raw data has been kept under lock and key? Should @NSF require that scientists to release old data as a prerequsite for future $$?
Colada[139] Artificial Deadlines Part 2
Evidence of fraud in the 25 year old gradesheet behind the key finding in an influential paper on deadlines and procrastination (Ariely & Wertenbroch 2002)
datacolada.org/139
The Metascience Observatory retweeted
Interesting effort to try to incentivize data sharing in science.
"NIH announces winners of S-index Challenge to advance data sharing across biomedical research"
nei.nih.gov/research-and-tra…
The winner was scholardata.io What are people's thoughts?
@NIH @NatEyeInstitute
The Metascience Observatory retweeted
For fun we're running the @MetascienceObs's forensic metascience agent on a number of papers on Cerebrolysin, a fake "peptide" drug. We're seeing contradictions between abstract text and data presented in the paper! Missing patients also. 3 PubPeer comments so far.. (link below)
