MD, PhD, hematologist @HopSaintLouis Professor of hematology @univ_paris_cite INSERM U1342 @Leukemia_Inst
Paris, France
Joined January 2022
- Tweets143
- Following270
- Followers290
- Likes192
Interested in human hematopoiesis, cell division and how clonal memory is disrupted in malignant hematopoiesis? Here is an amazing paper by Alessandro Donada and Leïla Perié that highlights how synchronicity of divisions is regulated during hematopoiesis
doi.org/10.1038/s41467-026-7…
David Michonneau retweeted
Facial erithema after allo-SCT. Not always GVHD. Great study led by @jessicotta1994. Take a look.
onlinelibrary.wiley.com/doi/…
David Michonneau retweeted
So excited to see this out! CellTune, our software for cell classification in Spatial Proteomics, is published in @naturemethods
nature.com/articles/s41592-0…
David Michonneau retweeted
Scientists uncover pre-treatment signatures in monocytes, myeloid cells, and T cells that predict corticosteroid resistance in patients with acute #GVHD, hinting steroid resistance is an intrinsic property of immune cells. @MichonneauDavid @Leukemia_Inst scim.ag/4cxL1sB
New in @ScienceMagazine
🧬 Thrilled to share our last paper
Corticosteroid resistance is predetermined by early immune response dynamics at acute graft-versus-host disease onset | Science Translational Medicine science.org/doi/10.1126/scit…
This work is the result of a truly collaborative effort between @inserm @Institut_IRSL @HopSaintLouis @APHP @Leukemia_Inst @Siric InSitu, @universiteparis @cryostem_FR
👏 I would like to thank all our collaborators, especially Sophie Le Grand for her outstanding scientific work and @nivallet, and all our funder @FLeucemieEspoir @fdmaladiesrares @HPNFranceAM Fonds de dotation CSL behring Siric InSitu and InIdEx immuno-oncology @univ_paris_cite
Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity | Science science.org/doi/10.1126/scie…
David Michonneau retweeted
Multiplexed imaging of acute GVHD gastrointestinal biopsies revealed epithelial remodeling and alteration in immune composition, offering insight into disease pathology
science.org/doi/10.1126/scit… @leeat_keren @WeizmannScience
Happy to share our last article in collaboration with @nofar_azulay and @leeat_keren @WeizmannScience in @ScienceTM A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology science.org/doi/10.1126/scit…
Diet outperforms microbial transplant to drive microbiome recovery in mice | Nature nature.com/articles/s41586-0…
Great collaboration with Robert Zeiser @Uniklinik_Fr @Leukemia_Inst @univ_paris_cite Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey | Bone Marrow Transplantation nature.com/articles/s41409-0…
AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling ashpublications.org/bloodadv…
Happy to share our last paper, published with @SpringerNature in @BMTjournal, about the French experience with belumosudil in the treatment of steroid-resistant cGvHD. Best ORR 57.4% including 14.7% of CR in patients who previously received at least 2 LOT
rdcu.be/efZg9
Thanks to all collaborators, French centers of #alloHSCT and to @SFGM_TC. @APHP @HopSaintLouis @Leukemia_Inst @univ_paris_cite