@MrinalS01

@ TIFR Hyderabad

 Hyderabad, Telangana
tifrh.res.in/~mrinals/
Joined May 2017
  • Tweets290
  • Following174
  • Followers202
3Media
Mrinal Srivastava retweeted
Cell@CellCellPress23h
Now online! Metazoan lagging-strand DNA synthesis is distributive dlvr.​it/TW3JSW
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Molecular Cell@MolecularCellOct 23
Online Now: PARP1 directly disassembles nucleosomes to regulate DNA repair dlvr.​it/TW2Hcb
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ICTS@ictstifrOct 23
Ashoke Sen has been awarded the prestigious Oskar Klein Medal for 2026, becoming the first Indian physicist to receive the honour. Previous recipients include Nobel laureates Chen-Ning Yang, Steven Weinberg and Hans Bethe, who received the medal in its first three years.
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Cell Press@CellPressNewsOct 22
A new collection from the @SMaHTnetwork is out in @CellCellPress and @CellGenomics laying the foundation for a catalog of somatic variation across human tissues.  Explore this exciting work: hubs.ly/Q04C2K4W0  #SMaHT #Genomics #SomaticMosaicism
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Mrinal Srivastava retweeted
Sagar Sengupta@DrSagarSenguptaOct 21
Our work in @EmboMolMed show two FDA approved small molecules rescue POLGA mediated aggregation and restore mitochondrial functions in a PEO mice model pubmed.ncbi.nlm.nih.gov/4283… PEO is a mitochondrial disorder affecting 0.05% of the world population. Thanks to the entire team.
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Mrinal Srivastava retweeted
Molecular Cell@MolecularCellOct 21
Online Now: Protein arginine methylation promotes global 3′UTR shortening in proliferating cells dlvr.​it/TW0p7v
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Molecular Cell@MolecularCellOct 21
Online Now: Regulatable in vivo gene expression via adaptamers dlvr.​it/TW0fpt
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Mrinal Srivastava retweeted
nature
@NatureOct 20
Nature research paper: De novo design of cysteine proteases go.nature.com/4zUMtOP

De novo design of cysteine proteases

Nature - De novo-designed enzymes use an activated cysteine nucleophile to hydrolyse polypeptide backbones in a sequence-dependent manner.

nature.com
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Mrinal Srivastava retweeted
Molecular Cell@MolecularCellOct 19
Structural compatibility is not enough: Current challenges in protein-protein interaction prediction. www.​cell.​com/molecular-cell/fulltext/S1097-2765(26)00619-2
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Mrinal Srivastava retweeted
Molecular Cell@MolecularCellOct 16
ATM safeguards DNA replication by restraining pathological repriming at endogenous base lesions dlvr.​it/TVxXCY
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Molecular Cell@MolecularCellOct 16
Simplifying in silico protein evolution with minimal screening by unZipro dlvr.​it/TVxSvy
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Mrinal Srivastava retweeted
Molecular Cell@MolecularCellOct 15
Artificial intelligence is rapidly transforming molecular biology. In this issue of Molecular Cell, we highlight recent advances at the intersection of AI and molecular biology, spanning structure prediction, design, genome engineering, and functional genomics.
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Mrinal Srivastava retweeted
Eric Topol
@EricTopolOct 15
We are all mosaics with our cells accumulating somatic mutations as we age. Now that is getting fully comprehensively quantified @CellCellPress cell.com/cell/fulltext/S0092…
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Mrinal Srivastava retweeted
Molecular Cell@MolecularCellOct 15
Online Now: Inherent electrochemical activity of extrachromosomal DNA hub shapes spatial redox environment in nucleus dlvr.​it/TVwlny
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Mrinal Srivastava retweeted
Nature Biotechnology
@NatureBiotechOct 12
Ten years, tens of millions of cells nature.com/articles/s41587-0…
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Mrinal Srivastava retweeted
IISc Bangalore@iiscbangaloreOct 9
The online application portal for Mid-Year Admissions 2026–27 is now open. Interested applicants may submit their applications from 06.10.2026 to 26.10.2026.
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Mrinal Srivastava retweeted
Molecular Cell@MolecularCellOct 8
Online Now: Mechanistic insights into chromatin modulation by the “orphan” remodeler ATRX dlvr.​it/TVqrRl
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Your next chapter in fundamental research could start here. Applications are now open for TIFR Graduate School GS-2027, the nationwide entrance examination for PhD and Integrated MSc-PhD programmes at TIFR centres across India. From understanding living systems to exploring the laws of nature, building intelligent systems and advancing mathematical sciences, GS-2027 offers research opportunities across a wide range of disciplines. Programmes include: Biology | Chemistry | Computer Science | Learning, Information & Data Sciences (LIDS) | Mathematics | Physics | Applied Computational Math | Physics of Life | Science Education 📝 Exam on 13 Dec 2026 🗓️ Apply by 25 Oct, 11 PM Fee Waiver Deadline: Oct 11, 11 PM Ready to apply? Scan the QR code or visit: tifr.link/gs-admissions Explore the programmes, eligibility requirements and FAQs before applying. #TIFRGS2027 #GraduateSchool #PhD #Research #Science #HigherEducation #ScienceCareers #Admissions
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Mrinal Srivastava retweeted
Whetstine Lab@WhetstineLabOct 2
How does MYC go from 2 copies to an amplified oncogene? 🧬🔬 Our New pub now @MolecularCell investigating how #epigenetic regulation controls genesis & progression of #MYC amplifications @brkthroughprize @NIH @CeiFccc cell.com/molecular-cell/abst… @nytimes nytimes.com/2026/10/02/scien…

An epigenetic program dictates MYC amplification dynamics that promote transient, extrachromosomal,...

Ferman et al. demonstrate that epigenetic imbalance directly controls MYC oncogene amplification dynamics, which identifies possible biomarkers and therapeutic targets for aggressive tumors. When a...

cell.com
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Mrinal Srivastava retweeted
Nature Chemical Biology@nchembioOct 7
High-resolution NMR spectroscopy of proteins in intact mitochondria nature.com/articles/s41589-0…
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