Assistant Professor @UPMCHillmanCC | @DamonRunyon Dale Frey Scientist | microbiome & immunotherapy | follow your gut | she/her/hers | views are my own
Pittsburgh, PA
Joined April 2010
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Very excited to share our latest paper, out today in Cell, led by @ItzDipyaman! This project started out with a curiosity as to how and why irAEs happen. Even more peculiar is that WT mice never develop irAEs…and why was that?
cell.com/cell/fulltext/S0092…
Using our model, Lifestyle Induced Susceptibility to immune related Adverse events “LISA”, to better understand and hopefully treat irAEs.
A huge thanks to our amazing collaborators and funding from @DamonRunyon @NIH @PittsburghFdn @UPMCHillmanCC and others. And of course, thank you to LISA.
Overacre Lab retweeted
💡 What sets the size of a germinal center? — why lymphatics of course 😉
Our new study with Carla Nowosad reveals how lymphatic remodeling constrains germinal center growth and shapes the quality of the antibody response. @ImmunityCP @nyugrossman
cell.com/immunity/fulltext/S…
Proud of these two stellar PhD students for their awards at our recent departmental retreat! @Kate_Wolfgang_ @jessica_jana_
Overacre Lab retweeted
Announcing the launch of the Mario Lemieux Microbiome Innovation Center at @UPMCHillmanCC & @PittTweet! Through a $5M commitment from the Lemieux Foundation, matched with an additional $1M from UPMC, this center will advance microbiome research. Read more: mariolemieux.org/microbiome-…
Overacre Lab retweeted
WTH is wrong with Russ Vought!?! Some personal vendetta against NIH and biomedical research? He is slowing scientific progress, massively undermining our global competitiveness, and because of him, we will have fewer new therapies for disease
nytimes.com/2026/09/20/scien…
Apply and join us for a fantastic program!
Applications are now open for the SITC Sparkathon Class of 2027, focused on the next generation of cellular therapies! Connect, collaborate and grow your career. Apply today: sitcancer.org/career-develop…
Overacre Lab retweeted
Stellar viewpoint from Ira on the current status of cancer immunotherapy - takeaway message: small biotech and academia will need to continue to keep the candle lit for immuno-oncology, and more mechanistic studies will be needed to find the next big thing nature.com/articles/s41577-0…
Always a great time!
Thrilled to cut loose with the lab for our @OveracreLab vs @DelgoffeLab Lab Olympics 2026! Popular events include chair curling, wet glove races, pipet javelin, and a contentious parafilm stretch competition!
Had a fantastic time at @socmucimm #ICMI2026 with @jessica_jana_ and @Kate_Wolfgang_ in Montreal! A wonderful few days of sharing our work and learning so much. Until next time!
Overacre Lab retweeted
Announcing the 2026 #SITC election results! Thank you to all of the candidates for their interest in serving the society, and to the members who voted. sitcancer.org/get-involved/2… #immunotherapy #cancerIO
Overacre Lab retweeted
Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ nature.com/articles/s41586-0…
Overacre Lab retweeted
Congratulations Dr. Finn, an amazing immunologist who continues her research on vaccines at UPMC Hillman & the University of Pittsburgh! @pitt_immunology @PittHealthSci @UPMCnews @UPMCPhysicianEd
It was an absolute honor to introduce Dr. Olja Finn as she received the AAI Distinguished Mentor Award @ImmunologyAAI this year. Olja, you are a pioneer in science, mentorship, and life. 👏💕💜 #IMMUNOLOGY2026 @UPMCHillmanCC @PittTweet
