The Pharmacogenetics To Avoid Loss of Hearing Trial | Supported by @NIHRresearch @RNID and @ManchesterBRC | Reporting March 2022
Manchester, England
Joined February 2019
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Thrilled that the @PALOH_Study has been published today in @JAMAPediatrics.
jamanetwork.com/journals/jam…
Over the next week we'll highlight the main findings, the potential benefits for patients, and what this means for rapid genetic testing in healthcare. More to come next week.
Big news!
PALOH-UK is introducing the PALOH study to neonatal units across the UK and we are recruiting for our Parent Advisory Group now!
Please see posters below for more details
The PALOH Trial retweeted
Huge congratulations to @GeneticBill, @John_H_McD and the PALOH team at @MFTnhs who won Research Project of the Year: STEM at @timeshighered Awards last night!
Winning #THEAwards Research Project of the Year: STEM is @OfficialUoM for creating the world’s first rapid bedside test to detect a gene for antibiotic-induced deafness in newborns, which the judges described as “a game changer for thousands of babies”👶
The PALOH Trial retweeted
Congratulations to the PALOH team! Winner of Research Project of the Year: STEM at the @timeshighered awards 2024 🏆
👏 @GeneticBill, @John_H_McD and all involved @OfficialUoM and @MFTnhs. @NIHRresearch @ManchesterBRC @MFT_Research
Winning #THEAwards Research Project of the Year: STEM is @OfficialUoM for creating the world’s first rapid bedside test to detect a gene for antibiotic-induced deafness in newborns, which the judges described as “a game changer for thousands of babies”👶
The PALOH Trial retweeted
Another incredible achievement for the PALOH team!
Winner of Research Project of the Year: STEM at last night’s @timeshighered awards 2024 🏆
Huge congratulations to all 👏
Winning #THEAwards Research Project of the Year: STEM is @OfficialUoM for creating the world’s first rapid bedside test to detect a gene for antibiotic-induced deafness in newborns, which the judges described as “a game changer for thousands of babies”👶
The PALOH Trial retweeted
Congratulations to the PALOH study team who won Research Project of the Year: STEM at the @timeshighered Awards 2024🏆👏.
The team developed the world’s first bedside genetic test that can prevent critically ill newborn babies from going deaf if treated with a common antibiotic.
Winning #THEAwards Research Project of the Year: STEM is @OfficialUoM for creating the world’s first rapid bedside test to detect a gene for antibiotic-induced deafness in newborns, which the judges described as “a game changer for thousands of babies”👶
Very proud to announce that tonight @PALOH_Study won the @timeshighered STEM award for @OfficialUoM #THEAwards
Winning #THEAwards Research Project of the Year: STEM is @OfficialUoM for creating the world’s first rapid bedside test to detect a gene for antibiotic-induced deafness in newborns, which the judges described as “a game changer for thousands of babies”👶
The PALOH Trial retweeted
🎆Congratulations to @GeneticBill @John_H_McD and the team at @OfficialUoM @MFTnhs on their nomination for STEM Research Project of the Year!
Winners will be announced on 28th November, we wish you all the best of luck!
the-awards.co.uk/2024/en/pag…
#GDR
The PALOH Trial retweeted
With £1.4m funding from @NIHRresearch and the @UK_Life_Science, PALOH-UK will demonstrate at a larger scale, how the test can be used in a timely way to ensure babies get a safe, effective antibiotic without affecting normal clinical practice.
👇
research.cmft.nhs.uk/news-ev…
The PALOH Trial retweeted
🗞️ A pioneering genetic test developed by @MFTnhs researchers, that could prevent critically ill newborn babies going deaf if treated with a commonly used antibiotic, is being trialled across 14 NHS specialist newborn units, in the new PALOH-UK study.
👇
research.cmft.nhs.uk/news-ev…
The PALOH Trial retweeted
The afternoon session at #ESPT23 is underway with @GeneticBill speaking about the use of point of care systems in pharmacogenetics - discussing our experience of the @PALOH_Study with @genedriveplc.
The PALOH Trial retweeted
@BSACandJAC #grammegative2023
Waiting to present on @PALOH_Study and use of point of care testing to avoid hearing loss in neonates
The PALOH Trial retweeted
We're pleased to announce our shortlisted nominees for this year's BAPM Gopi Menon Awards.
The winners will be announced on Tuesday 12 September at the BAPM Annual Conference.
You can find the full shortlist here>
bapm.org/pages/bapm-gopi-men…
The PALOH Trial retweeted
Great talk about rapid point of care testing to detect a genetic variant associated with aminoglycoside related ototoxicity. Potential for a huge impact in management of neonates with sepsis @PALOH_Study #rcpch2023
The PALOH Trial retweeted
World's 1st rapid test to identify a particular gene in babies +prevent antibiotic induced hearing loss -
now recommend by @NICEComms for use in @NHSuk
CE certified with potential US #FDA approval in the near future.
#gdr @genedriveplc @PALOH_Study @MFTnhs #neonatal #AIHL
A genetic test to establish if a newborn baby is vulnerable to deafness if treated with a commonly used antibiotic has been recommended by NICE in final guidance published today.
Learn more: nice.org.uk/news/article/nic… #NICENews
The PALOH Trial retweeted
Patients with the m.1555A>G genetic variant are at increased risk of deafness when treated with antibiotics called aminoglycosides.
Join our webinar to learn about the pharmacogenomic test for this variant:
📅 13 April 12-1pm
📅 10 May 1-2pm
Visit bit.ly/3KaZ5Kn
The PALOH Trial retweeted
Preventing Hearing loss Through Genetic Screening: Exploring Genedrive's Game Changing Technology. @genedriveplc #geneticscreening #hearinghealth #hearingloss #hearingcare youtu.be/ke3vSgB0tyU
The PALOH Trial retweeted
Kate uses the brilliant @PALOH_study to illustrate the issues, and you can read more about this in her fascinating article in @JME_BMJ:
jme.bmj.com/content/49/5/352
The PALOH Trial retweeted
As a society, we tend to focus a lot on risk and try to control it through regulation - but how well does that work in #genomic medicine?
@kvlyle talks to us about this in the 7th episode of the CPM podcast:
podcasts.ox.ac.uk/series-2-e…
The PALOH Trial retweeted
@John_H_McD @VidehaSharma @pmw777 building on @nwgmsa @PALOH_Study #PGx with many colleagues across @OfficialUoM @MFT_Research @HealthInnovMcr @DEVOTEProgramme
The DEVOTE Programme will develop new genetic tests that can give rapid results in minutes.
In collaboration with @OfficialUoM, this will bring together academic, industry and clinical partners across Greater Manchester.
Read more 👇
manchesterbrc.nihr.ac.uk/new…
The PALOH Trial retweeted
Patient and public involvement in #hearing research: opportunities, impact & reflections with case studies from #Manchester Centre for #Audiology and #Deafness
#OpenAccess by @PiersDawes, @KevinJMunro & colleagues with @ManCAD_UoM & @ManchesterBRC
tandfonline.com/doi/full/10.…
