Imagine a world where #pancreaticcancer is detected early, where patients are guided to the best care from the moment of diagnosis, and where discoveries move from the lab to saving lives in years, not decades. That is the future PanCAN is building — by bringing together patients, families, researchers and clinicians to transform the future of this disease. 💜 Today at #PanCANPurpleStride, we launch our most ambitious effort yet, the $250 million All Together We Can campaign. Our vision: to make survival the expectation, not the exception, for the tens of thousands of people diagnosed with this disease every year. Why now? Because this disease remains the deadliest major cancer and the only one with a five-year survival rate below 20%. Because patients and their loved ones deserve more time, more treatment options and more effective screening strategies. Because our community knows that when we’re united in purpose and vision, we can achieve anything — and we’re ready to take on this next chapter. Learn more about how, over the next five years, the All Together We Can campaign will invest across three strategic pillars — forming a comprehensive approach to accelerate progress and improve survival for pancreatic cancer patients at 🔗 pcan.at/all-together-we-can.

For Alyssa L., PanCAN's Associate Director of Philanthropic Engagement and Mid-level Giving, the mission to advance pancreatic cancer research and support patients and families hits close to home. 💜 She shares, "In January 2025, my dad was diagnosed with pancreatic cancer. I knew what people said about this disease. I had watched his mom, my grandmother, die just four months after her diagnosis in 2011. So, devastated, my dog and I moved home to make the most of the time we had left together. His initial diagnosis was stage IB. But when a Whipple procedure attempt in June 2025 revealed two small lesions in his liver, he was immediately elevated to stage IV, and the doctor estimated that he likely had only eight months to a year left. Since then, our family has been through more rounds of chemotherapy than I can count, CT scans, infections, a second failed Whipple surgery, setbacks and the agonizing uncertainty of waiting for results, return phone calls and the next appointment. If you’ve been touched by pancreatic cancer, you likely recognize this cycle of hope and grief. I knew I needed something that would get me out of bed in the morning. I felt desperate to contribute something positive and make meaningful progress for others facing this disease. That determination led me to PanCAN. Since joining the team here, I haven’t just learned about PanCAN’s mission and programs. I’ve experienced their impact firsthand. I’ve used PanCAN’s website and resources to become better informed. I’ve attended every webinar and listened to PancChat podcasts to deepen my understanding of the disease, the science and the treatment landscape. I attended my first PanCAN PurpleStride with my family and connected with other patients and caregivers, heard inspiring stories from survivors and experienced the power of a community united by hope. In conversations with our fundraising team, I’ve felt the authenticity, kindness and compassion that compels our supporters to give. My colleagues in PanCAN Patient Services answered my many questions, which strengthened both my work and helped me navigate conversations with my dad’s care team with far more clarity and confidence. When I prepared narratives about daraxonrasib and PanCAN’s decades-long role in propelling RAS research forward, I leaned heavily on my colleagues’ expertise to grasp the significance of this breakthrough. They also helped me understand the trial results and what they could mean for patients like my dad. So, when another liver lesion finally showed up on his imaging this July, I already knew our next step: trying to get him into the expanded access program (EAP) for daraxonrasib. On August 25th, when his paperwork was finally submitted, I felt hopeful knowing we were on the path to keep just barely outrunning this cancer for a little while longer. The next day, RASONQUE™ (daraxonrasib) was approved by the FDA. As PanCAN shared the exciting news, I was simultaneously panicking about what it might mean for my dad’s access, particularly after a month off treatment. Luckily, PanCAN’s Patient Services team provides personalized guidance for people exactly like me. I called, and they knew what my next steps should be. On their guidance, we got back on track to access the treatment through insurance. Colleagues had already been checking in because they knew others were running into access issues, and they were hard at work telling the story of how to better advocate for patients and their loved ones. So I wasn’t all that surprised when my dad was denied coverage. After a firm discussion with the insurance company, and armed with the knowledge I’d gained from Patient Services, we received a reversal — and RASONQUE arrived at our door the next day. My dad’s been on RASONQUE for a month, and his numbers are looking good. I know RASONQUE isn’t a cure. But right now, this treatment is giving my family renewed hope for more time. For more than 27 years, PanCAN President and CEO Julie Fleshman and Founder Pamela Acosta Marquardt have brought passion, unwavering dedication and ingenuity to PanCAN’s mission. Their commitment has been relentless, shaping and strengthening the field in countless ways. PanCAN’s willingness to be bold and innovative, to invest in RAS research 20 years ago when those mutations were considered undruggable, played a role in getting us to this moment. And the work we’re advancing today will continue to drive future breakthroughs for patients. I’m so honored to be a part of it. To my colleagues at PanCAN — and to everyone who donates, volunteers, walks, and advocates — you are changing people’s lives. I know, because I’m one of them." Join us in sharing some love and support for Alyssa and her family in the comments. 💜

Register for #PanCANPurpleStride 2027 and start reconnecting with your community, fundraising and making an impact toward a future where survival is the expectation, not the exception. 💜 Registering will give you access to your personal PurpleStride Dashboard. And this year, we’ve made fundraising easier than ever with the PanCAN Fundraising mobile app! The Dashboard and the app are your one-stop shop for your fundraising needs, but the app has bonus features you should take advantage of, like: 🔎 A personal QR code Your app gives you a unique QR code that links directly to your Personal Fundraising Page. Display it, download it or share it — supporters can simply scan and donate. 💬 Reaching supporters by text or WhatsApp Send pre-written fundraising messages to your network by text or WhatsApp, in addition to email. 📲 Sharing wherever you’re social Copy your Personal Fundraising Page link and share it on Instagram, Facebook, LinkedIn or TikTok. And it’s not just convenient — Striders who use an app to fundraise raise 2.4 times more than those who don’t! Register at 🔗 purplestride.org, then download the PanCAN Fundraising app today!

Take the trip of a lifetime climbing to the roof of Africa while creating a world where every patient with pancreatic cancer survives. Join an exclusive, first-class charity trek, fully guided by our excursion partner Embark Exploration Co., and discover what’s possible when purpose meets adventure. 💜 Ready to learn more? Register for our PanCAN Summit for Survival: Kilimanjaro 2027 Information Session at 🔗 pcan.at/adventure.

Today, we remember @NBA referee Tony Brown on the anniversary of his passing from pancreatic cancer. He was 55. Tony’s daughter, PanCAN Ambassador Bailey Taylor Brown, honors her dad’s legacy by raising awareness, fundraising in his memory and leading Team Tony Brown #6Strong at #PanCANPurpleStride. Thank you, Bailey, for allowing us to honor and remember your dad alongside you. 💜 Join us in sending love to the Brown family, the @OfficialNBARefs and everyone who knew and loved Tony in the comments. Learn more about pancreatic cancer and how, together, we can turn survival into the expectation, not the exception, for everyone facing this disease at 🔗 pancan.org.

PanCAN volunteers are hope in action. 💜 PurpleStriders leaders, Volunteer Advisory Council (VAC) members and National Volunteer Awards recipients from across the country recently came together in Dallas for our National Affiliate Forum. Together, they built connections, learned from one another, honored their whys and explored ways to lead with impact, raise mission-critical funds in their communities and advance PanCAN’s mission to turn science into survival. Each #PanCANvolunteer also received a heartfelt, handwritten note from a pancreatic cancer researcher or clinician, written weeks earlier at our Scientific Summit — a meaningful reminder that we’re all part of something bigger and that, all together, we can change the story of this disease. Want to make a difference in your community? Visit 🔗 pancan.org/getinvolved to learn more about becoming a PanCAN volunteer!

This year, we celebrated a group of outstanding PanCAN volunteers who exemplify leadership, service, community-building and commitment to our mission. We’re proud to share the recipients of our inaugural PanCAN National Volunteer Awards. Congratulations to Steve M., Community Chair for our New Jersey Affiliate, on receiving the Randy Pausch Award! 📣 Please join us in congratulating #PanCANvolunteer Steve in the comments and celebrating his dedication to the PanCAN community! 💜

This year, we celebrated a group of outstanding PanCAN volunteers who exemplify leadership, service, community-building and commitment to our mission. We’re proud to share the recipients of our inaugural PanCAN National Volunteer Awards. Congratulations to the Michigan Affiliate on receiving the Outstanding Affiliate of the Year in Honor of Andy Bittman and Andy’s Avengers! 🏆 Please join us in congratulating each #PanCANvolunteer from our Michigan Affiliate in the comments and celebrating their dedication to the PanCAN community! 💜

This year, we celebrated a group of outstanding PanCAN volunteers who exemplify leadership, service, community-building and commitment to our mission. We’re proud to share the recipients of our inaugural PanCAN National Volunteer Awards. Congratulations to Annette F., Social Media Chair for our Pittsburgh Affiliate, on receiving the Sparkle Spirit Award! ✨ Please join us in congratulating #PanCANvolunteer Annette in the comments and celebrating her dedication to the PanCAN community! 💜

This year, we celebrated a group of outstanding PanCAN volunteers who exemplify leadership, service, community-building and commitment to our mission. We’re proud to share the recipients of our inaugural PanCAN National Volunteer Awards. Congratulations to Carly H., Mission Chair for our Colorado Affiliate, on receiving the Rising Star Award! 🌟 Please join us in congratulating #PanCANvolunteer Carly in the comments and celebrating her dedication to the PanCAN community! 💜

This year, we celebrated a group of outstanding PanCAN volunteers who exemplify leadership, service, community-building and commitment to our mission. We’re proud to share the recipients of our inaugural PanCAN National Volunteer Awards. Congratulations to Debbie H., PurpleStride Chair for our Colorado Affiliate, on receiving the PurpleStride Leadership Award in Honor of Leslie Hume! 👟 Please join us in congratulating #PanCANvolunteer Debbie in the comments and celebrating her dedication to the PanCAN community! 💜

This year, we celebrated a group of outstanding PanCAN volunteers who exemplify leadership, service, community-building and commitment to our mission. We’re proud to share the recipients of our inaugural PanCAN National Volunteer Awards. Congratulations to Mimi L., Advocacy Chair for our Colorado Affiliate, on receiving the Community Builder Award! 🏆 Please join us in congratulating #PanCANvolunteer Mimi in the comments and celebrating her dedication to the PanCAN community! 💜

Questions about pancreatic cancer? PanCAN Patient Services Case Managers can help. 💜 Our highly trained professionals offer personalized, one-to-one guidance and connect you with the information, services and support you need. No question is too big or too small. Here are just a few of the ways our team can help: 1️⃣ Finding a pancreatic cancer specialist. Seeing a pancreatic cancer specialist improves outcomes. Our team maintains a list of physicians in locations across the country who diagnose and treat a high volume of patients with pancreatic cancer. 2️⃣ Getting biomarker testing.PanCAN's Know Your Tumor service provides eligible patients with information about their tumor's biology through free tissue biomarker testing. Patient Services can answer questions about the program, help you understand results and give you information on treatment options, including clinical trials. 3️⃣ Exploring clinical trials.PanCAN maintains the most comprehensive and up-to-date database of pancreatic cancer clinical trials available in the United States. Our Case Managers can provide resources and support as well as run a personalized clinical trial search. 4️⃣ Connecting with others affected by this disease. There is nothing quite like talking to someone who has faced similar challenges. Share information, ask questions and gain inspiration through PanCAN's Survivor & Caregiver Network. Our Case Managers can match you with a survivor or caregiver who has volunteered to connect one-to-one with individuals diagnosed with pancreatic cancer or their loved ones. Contact PanCAN Patient Services today at 🔗 pancan.org/patientservices.

ICYMI: Yesterday, PanCAN Chief Scientific & Medical Officer @ABerkenblit, MD, MMSc, hosted the second event in PanCAN’s Right Track Live series, featuring a panel discussion to help patients, caregivers and loved ones better understand pancreatic neuroendocrine tumors (PNETs). Watch or rewatch the event now. 💜 youtube.com/watch?v=bKUxv8u1…

We are saddened by the passing of Rachna T. Shroff, MD, MS, a renowned physician-scientist who treated people with pancreatic cancer and advanced treatment options for patients facing pancreatic and hepatobiliary cancers. Dr. Shroff passed away following a battle with an aggressive cancer. She was 47. Through her groundbreaking research and leadership in clinical trials, Dr. Shroff helped move the field forward and expand possibilities for patients. She also collaborated with PanCAN on research related to our Know Your Tumor® precision medicine service, contributing to a deeper understanding of pancreatic cancer. We extend our heartfelt condolences to her loved ones, colleagues and the many patients whose lives she touched. 💜 Read more from the @UAZMedTucson at 🔗 bit.ly/4jprjTS.

Strider Breana D. shares, "We’re back and raising money for the Pancreatic Cancer Action Network in honor of my mom, Monika Donnelly. My mom was diagnosed with pancreatic cancer at just 49 years old, despite being incredibly healthy. Pancreatic cancer is often found late, in part because there’s no standard early detection test for the general population. The five-year survival rate is just 13%. We’re raising money to support breakthrough research, expand patient services and advocate for change that can improve survival rates. My mom was far too young, and we miss her so much. This is one way we can honor her and help other families facing this disease. I'm so proud to say that in just the past 3 years [at PanCAN PurpleStride], we've raised over $10,000 in honor of my mom. Our goal this year is $3,000." Join Breana in ending pancreatic cancer at our biggest community event of the year, #PanCANPurpleStride! 👟💜 Register today at 🔗 purplestride.org.

Join us tomorrow, October 15, for our virtual event focused on helping patients, caregivers and loved ones better understand pancreatic neuroendocrine tumors (also known as PNETs) and what recent advances mean for those affected by the disease. We will bring together leading PNET experts to share the latest information, answer common questions and provide practical insights into diagnosis, treatment and ongoing research. You’ll learn more about: 💜 How PNETs differ from the most common type of pancreatic cancer, including how they develop and why care often requires a specialized treatment approach. ⚠️ Common signs and symptoms that are unique to PNETs, including symptoms related to hormone changes that may be overlooked. 💊 Current treatment approaches and what patients should know about available targeted therapies and clinical trials. 🔬 Advances in PNET research and what it means for patients, including how to prepare for informed conversations with healthcare providers about treatment options and goals of care. Save your seat at 🔗 pcan.at/RightTrackLive.

Today marks one year since the passing of D’Angelo, Grammy-winning singer-songwriter and neo-soul pioneer, who died from pancreatic cancer at age 51. In 2026, an estimated 67,530 people in the U.S. will be diagnosed with pancreatic cancer and approximately 52,740 will die from the disease. Learn more about pancreatic cancer and how PanCAN is turning science into survival at 🔗 pancan.org. 📷: People

“Kelly was more than my best friend. She was my person, my confidant and my sounding board.” 💜 For #PanCANVolunteer Kecia S., pancreatic cancer has been part of her story since before she was born. Her grandfather was diagnosed two months before her birth and lived long enough to celebrate her first Christmas. Decades later, Kecia became the 24/7 caregiver for her best friend, Kelly, following her pancreatic cancer diagnosis in 2022. “It was a silent monster.” Kelly survived for five months. During that time, Kecia cared for her through treatment and hospice, an experience she describes as “the honor of a lifetime.” “She embodied the word hero. She was courageous and did everything with class and dignity.” After Kelly’s death, Kecia knew she needed to channel her grief somewhere. Having spent so much time caring for her best friend, she wasn’t ready to stop. She connected with a PanCAN volunteer and found a way to continue caring for others in Kelly’s honor. “I needed to do something so I could still feel like I was taking care of Kelly. Volunteering with PanCAN is the way I can do it.” Today, Kecia helps bring the Pittsburgh PanCAN community together through #PanCANPurpleStride, serving as the Pittsburgh Affiliate’s Event Day Volunteer Chair. “Kelly’s life still matters. It still has purpose and has led to a ripple effect of caring.” Read Kecia’s story and learn how she continues to honor the people she loves through volunteering with PanCAN at 🔗 pcan.at/gaxde8ei.

What if your next adventure could help patients with pancreatic cancer thrive? 💜⛰️ PanCAN has partnered with Embark Exploration Co. to take a select group of supporters in October 2027 to the summit of Mount Kilimanjaro — the highest peak in Africa and one of the world's most iconic trekking experiences. Join our first virtual information session on Wednesday, November 4, to learn more about this extraordinary opportunity. Visit 🔗 pcan.at/adventure to register for the information session and get trip details.