@PatByrne0

Science will win!

 Rockville, Maryland, USA
scholar.google.com/citations?hl=en&user=FkA6TtAAAAAJ&view_op=list_works&sortby=pubdate
Joined May 2022
  • Tweets256
  • Following325
  • Followers152
3Media
Please check out a paper from my postdoc @McLellan_Lab @ut_mbs, “Prefusion stabilization of the Hendra and Langya virus F proteins”, now available online @JVirology. This was a collaboration with Rebecca Loomis @NIAIDNews and @BarneyGrahamMD @MSMEDU journals.asm.org/doi/10.1128…

Prefusion stabilization of the Hendra and Langya virus F proteins | Journal of Virology

Pathogenic henipaviruses such as Nipah virus (NiV) and Hendra virus (HeV) cause respiratory symptoms, with severe cases resulting in encephalitis, seizures, and coma. The work described here shows...

journals.asm.org
3
12
1
40
6,551
This essay is a tribute to my friend Lee, who was the last person to have ever wanted a tribute written about her. Lee changed the world and I miss her: theatlantic.com/ideas/archiv…

The Woman Who Didn’t See Stuttering as a Flaw

Remembering Lee Caggiano, the woman who made me want to talk

theatlantic.com
1
15
3
74
39,490
Excited to collaborate on this study! Very interesting new antibodies that potently neutralize CMV.
Klein Lab@FKlein_Lab15 Nov 2023
Excited to share our latest publication @ImmunityCP: "Analysis of the Human B Cell Response to HCMV in Top Neutralizers from a cohort of 9,000 Individuals"! Congrats to @zehner_matthias, @Ashurov_Art and Mira and thanks to all collaboration partners! sciencedirect.com/science/ar…
7
40
6,975
Dear #cryoEM community - we are looking for nominations for leadership in the #cryoEM subgroup at the annual Biophysical Society 2025 meeting. Please nominate yourself or others who are willing! We are looking for a chair, faculty program committee members, and postdocs👇
5
16
34
9,486
Patrick Byrne retweeted
Caroline Kikawa@CKikawa11 Nov 2023
My first, first-author research article was published yesterday in @JVirology! doi.org/10.1128/jvi.01414-23 Excited to share our work measuring the effects of single flavivirus mutations on antibody neutralization, led by me w/ @jbloom_lab and @lesliegoo_lab guidance 🧵...

The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibod...

The wide endemic range of mosquito-vectored flaviviruses—such as Zika virus and dengue virus serotypes 1–4—places hundreds of millions of people at risk of infection every year. Despite this, there...

journals.asm.org
2
9
33
8,604
Jane S. Richardson et al.: The bad and the good of trends in model building and refinement for sparse-data regions: pernicious forms of overfitting versus good new tools and predictions #CaBLAMValidation ... #IUCr scripts.iucr.org/cgi-bin/pap…
23
2
77
15,451
Although tryptophans form the most pi-pi interactions per 100 residues (~48) only 15% of tryptophans on average form pi-pi interactions. Tyrosine, phenylalanine, arginine (all ~25%) and glycine (~20%) all have higher frequencies per pi-pi interaction.
1
18
127
12,870
👀 "Structural basis of dimerization of chemokine receptors CCR5 and CXCR4" nature.com/articles/s41467-0…

Structural basis of dimerization of chemokine receptors CCR5 and CXCR4

Nature Communications - Here, authors report chemokine receptors structures obtained using coarse-grained metadynamics. CCR5 and CXCR4 homo- and heterodimers differ in the conformations of ligand...

nature.com
3
10
1,602
One of my favorite spots in Texas! Have you been?
3
1
22
1,270
My babies are the October Molecule of the Month pdb101.rcsb.org/motm/286
9
30
1
220
18,817
Patrick Byrne retweeted
Sarah Zhang@sarahzhang22 Sep 2023
A virus called RSV is the #1 reason babies are hospitalized—yes, ahead of flu and COVID—but we couldn't do much about it until now. I nerded out a bit on how we went from zero vaccines for RSV in 2022 to multiple vaccines in 2023. This science is cool. theatlantic.com/health/archi…

A Truly Amazing Vaccine Breakthrough Is Hiding in Plain Sight

The COVID shots—and new ones for RSV—herald a new era for designing vaccines.

theatlantic.com
6
61
1
188
40,071
We finally got our long-awaited rain. Time to release some bats! . . #easternredbats #lasiurusborealis #leafbats #urbancanopy #batslivehere #batsaregoodneighbors #austinbats
2
58
6
251
28,466
Patrick Byrne retweeted
Tyler Starr@tylernstarr14 Sep 2023
Twitter may be dying, but the Starr lab is coming to life! We put out the first preprint from the lab @UofUBiochem, where we performed deep mutational scans on the SARS-CoV-2 BQ.1.1 and XBB.1.5 variant RBDs 🧵 biorxiv.org/cgi/content/abst…
4
43
4
183
34,880
The corner of 24th and Nueces post Texas’ victory over Alabama – at Austin, TX
25
247
91
2,594
304,449
Patrick Byrne retweeted
Matt Higgins@ParasiteMatt20 Jun 2023
How does the malaria parasite, Plasmodium vivax get inside human blood cells? In this manuscript we reveal the essential interaction between the parasite PvDBP protein and the human receptor DARC. The final paper is now on line if you missed the preprint. rdcu.be/deTaO
3
30
1
87
16,752
Patrick Byrne retweeted
Saloni
@salonium7 Sep 2023
My new favourite chart: A timeline of how many vaccines weʼve discovered & when. Note: 80 year gap between the 1st & 2nd vaccine. The vaccine against smallpox virus was developed before people knew what viruses were, *before germ theory had developed* Then discovery took off.
19
332
44
1,139
175,867
Patrick Byrne retweeted
Jay Hartzell
@JCHartzell7 Sep 2023
This is a great day for @UTAustin, @UTDiscoveries and Austin as the next major hub for life sciences! I am thrilled that UT and Karlin can be at the forefront of this movement and make an enormous impact on the city and the world #WhatStartsHere utex.as/3ZaISei

New Lab Space for Discovery to Impact Will Support Life Science Startups - UT News

AUSTIN, Texas — The University of Texas at Austin and Karlin Real Estate, a global real estate investment and development firm, are teaming up to launch

news.utexas.edu
9
3
43
22,394
Patrick Byrne retweeted
Hideaki E. Kato@emeKato30 Aug 2023
Our paper is finally out in Cell! cell.com/cell/fulltext/S0092… During the revision, we solved one more structure (H225F or KALI), performed more electrophysiological, computational, spectroscopic, and biochemical experiments, and conducted optogenetics experiments using KALI. (1/n)
6
69
9
302
117,859
Patrick Byrne retweeted
KUT Austin@KUT25 Aug 2023
For six decades, there was no approved vaccine for one of the most common causes of severe illness in infants, young children and older adults: RSV. Until now. Among the scientists responsible for this discovery is @UTAustin professor Jason McLellan. l8r.it/psHG

RSV vaccine for pregnant women could change the game for a common illness, UT Austin scientist says

The new vaccine is the latest in a series of preventive treatments for the virus that is the leading cause of hospitalization in infants.

kut.org
7
38
8,730
Load more