Super Saiyan of Pharmacy YouTube: https://teapaw.org/t.co/z0CxaNvkkF
Chicago, IL
Joined February 2022
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What happens when the mortality benefit of a miracle sepsis drug suddenly… disappears? Join me for a quick discussion on Xigris and the origins of Surviving Sepsis!
Xigris, Eli Lilly, and the Surviving Sepsis Marketing Machine youtube.com/shorts/DK98XJbV4… via @YouTube
CRE without carbapenemase production? More of that please! Today, let’s talk about CRE invasive infections when we catch a huge break!
#pharmacist #pharmacy #IDPharmacist #IDSA #CRE
youtube.com/shorts/o3q_hDwc0…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
1/11 #IDTwitter #IDXposts
Pharmacists keep telling you: “Why not use cefadroxil instead of cephalexin?"
After all, it has a longer half-life (1.5-2 hrs vs 1 hr), BID dosing. It sounds great!
But what about transitioning to complete therapy in gram-negative infections?
A cefadroxil PKPD review... 🧵
Working up ICU patients can be a daunting task for new pharmacists, but a systematic approach can break things down into manageable pieces can help – not unlike solving the humble Rubik’s cube!
#Pharmacist #ICUPharmacist #PatientWorkup #RubiksCube
youtu.be/GhuRPNNsnGI
We’ve covered the three easy to treat UTIs, and now on to the really f*!@in’ complicated one! Can we really afford to mess around with complicated CRE UTIs?
#pharmacist #pharmacy #IDPharmacist #IDSA #CRE
youtube.com/shorts/jasHmE9XC…
Mixing metronidazole and alcohol has been a big no-no for years – but is this based on any real evidence? Let’s take a deep dive into the shallow pool of data!
#Pharmacist #Pharmacy #Mythbusting
youtube.com/shorts/6yzNKhOsB…
Let’s take a look at the Surviving Sepsis Guidelines and see just how often blood cultures hit, and what we can do to get the most out of them!
#Pharmacist #Pharmacy #Sepsis #ICUPharmacist #IDPharmacist
youtube.com/shorts/3O1zS-MZl…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
🆕🔥🟢FAST-ROCKET
A multicenter, retrospective study(N:639)
The first study to compare clinical outcomes between patients who received cefepime & meropenem in a subset of patients with AmpC-ECK E bacteremia expressing baseline ceftriaxone resistance(MIC > 1 µg/mL)
🔺Among patients infected by ceftriaxone-resistant AmpC-E, carbapenems were used as definitive treatment in 30% (65/214), while cefepime was used for definitive treatment in 41% (88/214)
🔺After propensity score weighting, no statistically significant difference in 30-day mortality (HR, 1.08; 95% CI, 0.49–2.39; P= 0.848) was observed between patients infected by ceftriaxone-resistant AmpC-ECK E who received definitive treatment with meropenem or cefepime #IDXposts
sciencedirect.com/science/ar…
Treating CRE is no joke, so why is IDSA joking around? A lot of these suggestions are a roll of the dice – probably not the way I would go if I was writing a gram negative guidance document!
#pharmacist #pharmacy #IDPharmacist #IDSA #CRE
youtube.com/shorts/QXm0wco8D…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
Fosfo for pyelo letter/meta-analysis is published. doi.org/10.1093/cid/ciag552
Surely, it can't be CRE... but sometimes, it is! Let's talk about resistance mechanisms and some background for CRE!
#pharmacist #pharmacy #IDPharmacist #IDSA #CRE
youtube.com/shorts/HpXvh00vG…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
However...... May I share this preprint?
medrxiv.org/content/10.64898…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
Join us at #AMCP2026 in San Diego!
I'll be presenting alongside Dr. Alex Sandhu and Dr. Bridget O'Connell on secondary CVD risk, and sharing recent updates on lipid management.
@amcporg #AMCPNexus
amcpnexus.org/
Surviving Sepsis 2026 was a bit dense - so let's break it down! First up, let's talk about scoring systems!
#Pharmacist #Pharmacy #IDSA
youtube.com/shorts/-Tjmnz-WU…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
Join @PharmDFarmD and I as we discuss new-onset AFib in the ICU! Should we anticoagulate or hold off? Let’s look at the data!
A short acting drug that suddenly develops a long half-life? That’s fentanyl! Let’s talk about fentanyl infusions!
#Pharmacist #Pharmacy #Fentanyl #ICUPharmacist #SAT
youtube.com/shorts/3gB1EJ_bf…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
Updated Shorter Is Better tables! @absteward found a 2 wk vs. 12 wk 2-stage PJI RCT. Also @rachelpbaden identified a duplication in the CAP trials, so there are now 14 RCTs for CAP, not 15. Updated refs at
bradspellberg.com/shorter-is…
When they look right… You go left! Why bother with beta lactamase inhibitors and new drugs when we can cover AmpC with non-beta lactams! Let’s take a look at our options!
#pharmacist #pharmacy #IDPharmacist #IDSA #AmpC
youtube.com/shorts/1SDvNIRzS…
Happy pharmacy week!
Come join me and several other pharmacists as we discuss some of our favorite things about being pharmacists!
instagram.com/reel/DeqTyvCOt…
New Beta Lactams and Beta Lactamase Inhibitor Combos for AmpC-E? Hold your horses there, buddy! While these drugs may work, we probably have some better options!
#pharmacist #pharmacy #IDPharmacist #IDSA #AmpC
youtube.com/shorts/pvtoNSsnh…
Andrew Desio, PharmD BCPS BCCP BCCCP BCIDP retweeted
There is no standardized treatment catastrophic brain injury (CBI), a fatal injury. Giving dopamine, DDAVP, vasopressin, levothyroxine, or steroids alone: ↑ odds of organ donation after CBI. DDAVP and steroids together have the highest odds of successful donation.
@KristenNordham @STaghaviMD
ovid.com/jnls/jtrauma/abstra…
