We’re elated to share our most recent work on how procoagulant platelets promote venous thrombus formation, now out in @BloodJournal! ashpublications.org/blood/ar…

Check out the final version of our state-of-the-art review on platelet-mediated inflammatory hemostasis, now out @BloodJournal. Beautiful cover art by @NieswandtLab! @nicolai_leo @REscaig @Cardio_LMU @YoungDZHK @Herzstiftung @EKFStiftung @LMU_Uniklinikum

Happy to share our state-of-the-art review now out in @BloodJournal: We summarize evidence that distinguishes the fascinating platelet mechanisms and signaling events that mediate inflammatory hemostasis: ashpublications.org/blood/ar…

We propose a cascade of crucial platelet effector functions, initiated by platelet priming, that leads to local accumulation of single platelets. Haptotaxis and migration aid in strategic repositioning, to identify vascular injuries...

... at sites of neutrophil transmigration, where platelets use distinct signaling cascades to exert effector functions (including degranulation and procoagulant activation) to plug vascular microinjuries.

All of this builds on pivotal work by different expert groups in the field, including @NieswandtLab @plateletcarsten @StegnerLab @JulieRayes @BergmeierLab @WilburLam and many others! 🩸

Time again, great fun working with @nicolai_leo and our talented MD student @REscaig. @Cardio_LMU @MCSP_LMU @LMU_Uniklinikum @Herzstiftung @EKFStiftung @dzhk_germany @YoungDZHK

We made it - migrating and procoagulant #platelets on the cover of @BloodJournal. 🤩 Beautifully written editoral by Madhumita Chatterjee and more exciting hematology. Make sure to check it out!

@nicolai_leo @REscaig @dzhk_germany @YoungDZHK @Herzstiftung @Cardio_LMU @MCSP_LMU @KPekayvaz @LMU_Uniklinikum @dfg_public

Several amazing members of our lab have to be thanked for this, especially my colleague and friend @nicolai_leo, our super-talented MD student @REscaig, Afra Anjum, and Dr. Marie Hoffknecht (not on twtr yet), @KPekayvaz ... (8/9)

We’re excited to share our dive into inflammatory hemostasis, featuring a prominent role for #procoagulant #platelets – now online @BloodJournal. tinyurl.com/procplts 1/9

Check out our recent Review on the dynamic interplay of neutrophils and platelets, with a focus on (cardio)vascular disease and #COVID19. @nicolai_leo @REscaig @dzhk_germany @YoungDZHK @Cardio_LMU

Excited to share our most recent work on the contribution of prothrombotic, IL-8-driven neutrophils to severe #COVID_19 along with experimental insights into therapeutic targeting of IL-8 signaling for this deadly disease. A great piece of interdisciplinary team work ... (1/n)