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Lavilla Lab

@RLavillaGroup

New Chemical Methodologies for Facilitated Biology-Oriented Synthesis | @Farmacia_UB @IBUB_UB | @UniBarcelona

 Barcelona, Spain
ub.edu/medicinalchemistrypharmacology/research-group/rodolfo-lavilla/
Joined November 2019
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Photo by Lavilla Lab (@RLavillaGroup)Photo by Lavilla Lab (@RLavillaGroup)Photo by Lavilla Lab (@RLavillaGroup)Photo by Lavilla Lab (@RLavillaGroup)
As our #MCRCharting project continues, here is our new story @ACSCentSci. Congratulations to Pau, Fredrick, Marina and all of our collaborators for making it possible! @IBUB_UB @Farmacia_UB @RLavillaGroup pubs.acs.org/doi/10.1021/acs…
A Multicomponent Reaction-Based Platform Opens New Avenues in Aryl Hydrocarbon Receptor Modulation

A Multicomponent Reaction-Based Platform Opens New Avenues in Aryl Hydrocarbon Receptor Modulation

Abstract. A multidisciplinary platform is presented to address aryl hydrocarbon receptor (AhR) modulation. A rewired Yonemitsu multicomponent reaction with

pubs.acs.org
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Here is our new piece for Drug Discovery Today: "Drugs from drugs: New chemical insights into a mature concept" @RLavillaGroup @IBUB_UB #MulticomponentReactions #OpenAccess sciencedirect.com/science/ar…
Image from Ouldouz Ghashghaei (@GhashghaeiO)
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It has been an increadible experience to accompany Pau on his way to become Dr. Nadal. His dedication, hard work & creativity pushed forward our adventure on #MulticomponentReactions charting. @OlallaLab @dynafluors & J Luque many thanks for everything. tinyurl.com/mrxs734x
Pau Nadal successfully defended his PhD thesis - Medicinal Chemistry & Pharmacology

Pau Nadal successfully defended his PhD thesis - Medicinal Chemistry & Pharmacology

We are happy to announce that today Pau Nadal Rodríguez successfully defended his PhD thesis that was directed by Prof.…

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🎉 Enhorabona a tot el personal investigador de l’@IBUB_UB present al rànquing del top 2% de científics d’@Stanford 2024! Un orgull que catedràtics de la #FacultatdeFarmacia en formin part. 👏
Image from Facultat de Farmàcia i Ciències de l'Alimentació (@Farmacia_UB)
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Save the date! Super excited to be hosting Prof. Romano Orru at @Farmacia_UB on Thursday, Oct 3rd.
Image from Ouldouz Ghashghaei (@GhashghaeiO)
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Brought to Light: A Fluorogenic Probe to Monitor Immunosuppressants NEW #FirstReactions by Franziska Thomas​ at @UniHeidelberg discussing work by @marber_chem @dynafluors @RLavillaGroup go.acs.org/9OC Read it here: go.acs.org/9OD
Image from ACS Central Science (@ACSCentSci)
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#ICYMI Our NEW issue is now live! Read it here: go.acs.org/9zr Supplementary cover story by @marber_chem @dynafluors @RLavillaGroup go.acs.org/9zq
Image from ACS Central Science (@ACSCentSci)
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Avui estem a la #FestadelaCiència de la @UBDivulga, apropant a nens i nenes a la recerca amb el nostre taller “El fascinant viatge d’un medicament al nostre organisme”. Un any més, gaudint de la divulgació amb els més petits 👩🏽‍🔬🧑🏻‍🔬
Image from Noemí Martínez Conde (@n_martinezconde)
Image from Noemí Martínez Conde (@n_martinezconde)
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Site-selective labeling of the immunophilin FKBP12 using fluorogenic azo-functionalized BODIPYs allows rapid and wash-free detection of immunosuppressants @marber_chem @dynafluors @RLavillaGroup NEW #ASAP Read it here: go.acs.org/9bO
Image from ACS Central Science (@ACSCentSci)
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Lavilla Lab retweeted
IBUB-UB (@IBUB_UB) profile picture
IBUB-UB@IBUB_UB4 Apr 2024
#ArticleOfTheMonth I April 2024 📝Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressants 🔗Access the full article here 👉pubs.acs.org/doi/10.1021/acs…
Image from IBUB-UB (@IBUB_UB)
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The absolute joy to seeing our diazonium BODIPYs in action! Congratulations to everyone and big thanks to Marco, Lorena and @dynafluors for making it all possible. @RLavillaGroup @IBUB_UB
Marco Bertolini (@marber_chem) profile pictureMarco Bertolini@marber_chem21 Mar 2024
Have a look at our last paper in @ACSCentSci! We describe diazonium #BODIPY for the labelling of Tyr in peptides and proteins and the first #fluorogenic analogue of immunophilin #FKBP12 for the detection of #tacrolimus! #Chemistry #Fluorescence pubs.acs.org/doi/10.1021/acs…
Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosu...

Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosu...

Abstract. Immunosuppressants are clinically approved drugs to treat the potential rejection of transplanted organs and require frequent monitoring due to t

pubs.acs.org
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Reaction Space Charting as a Tool in Organic Chemistry Research and Development (Rodolfo Lavilla and co-workers) onlinelibrary.wiley.com/doi/…
Reaction Space Charting as a Tool in Organic Chemistry Research and Development

Reaction Space Charting as a Tool in Organic Chemistry Research and Development

The chemical and reaction spaces are incredibly vast and special procedures are required to study them. Their complex and multiparametric nature encompass myriads of compounds and interactions and...

advanced.onlinelibrary.wiley.com
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Lavilla Lab retweeted
IBUB-UB (@IBUB_UB) profile picture
IBUB-UB@IBUB_UB4 Sep 2023
📢Conferencia: "Estrategias verdes basadas en reacciones multicomponente: Síntesis de heterociclos peptidomiméticos" 🗣️Rocío Gámez Montaño, @UdeGuanajuato 📅12 de Septiembre 🕑12:00 📍A3, @Farmacia_UB Organiza: Rodolfo Lavilla @MCP_UB @craiubfcca
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Congratulations to Pau, Ouldouz (first paper as the corresponding author) and the whole team.
Angewandte Chemie (@angew_chem) profile pictureAngewandte Chemie@angew_chem5 Jun 2023
Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds (Rodolfo Lavilla and co-workers) @RLavillaGroup @GhashghaeiO @IBUB_UB @dynafluors #openaccess onlinelibrary.wiley.com/doi/…
Image from Angewandte Chemie (@angew_chem)
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During the Barcelona #BioMedConference on #TDP, Ouldouz presented an MCR-based approach for AhR activation and degradation. @GhashghaeiO #MulticomponentReactions
Image from Lavilla Lab (@RLavillaGroup)
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#editorchoice Efficient #AntiMycolata Agents by Increasing the Lipophilicity of Known #Antibiotics through #Multicomponent Reactions by Dr. Miguel Viñas and Dr. Concepción Alonso et al. mdpi.com/2079-6382/12/1/83
Image from Antibiotics MDPI (@antibioticsmdpi)
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Happy #WomenInScience day and loud cheers to our amazing team of scientists! #11F #WomenInScienceDay #DiaDonaINenaenCiència #MedChemUB @Farmacia_UB @IBUB_UB @UniBarcelona
Image from MedChemPharm Unit (@MCP_UB)
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The 3rd publication of our "Drugs from Drugs" project is online: Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through #MulticomponentReactions. mdpi.com/2047578 @antibioticsmdpi @mpedrola1 @GhashghaeiO #MedChemUB
Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multic...

Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multic...

New antibiotic agents were prepared using Povarov and Ugi multicomponent reactions upon the known drugs sulfadoxine and dapsone. The prepared derivatives, with increased lipophilicity, showed...

mdpi.com
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Lavilla Lab retweeted
IBUB-UB (@IBUB_UB) profile picture
IBUB-UB@IBUB_UB9 Jan 2023
The IBUB is seeking ealry stage researchers interested in pursuing their PhD in any of our research programs. If you are interested please contact our Principal Investigators or directly with us at [email protected]
Image from IBUB-UB (@IBUB_UB)
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Lavilla Lab retweeted
MCRs_UB (@UbMcr) profile picture
MCRs_UB@UbMcr16 Nov 2022
On Monday 21st, Ouldouz will be the guest lecturer of WCP2022, talking about heterocyclic MCRs in drug discovery. Onlibe Session link: solusiriset.com/21-november-…
[21 November 2022] World Class Professor Guest Lecture #3

[21 November 2022] World Class Professor Guest Lecture #3

solusiriset.com
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