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Massive 10+ year effort in lab spearheaded by @leonardoaparrar and Kayal (secret account 🤔). Unreal cover by @EmmaVIDALL that says it all.
2023's final issue is out! cell.com/neuron/current
Cover story is from @Roy_Lab_Thinks's lab revealing an unexpected physiologic role for α-synuclein phosphorylation in clustering synaptic vesicles and restricting neurotransmitter release. Read it here cell.com/neuron/fulltext/S08…
I'm obsessed with these empty clathrin cages people are seeing in neurons, and don't understand why others are not. So I put everything together and wrote a brief review (Current Opinion in Neurobiology, free access for 50 days):
sciencedirect.com/science/ar…
..pic above reproduced from @MishaKudryashev 's publication in PNAS.
Subhojit Roy, MD, PhD retweeted
1. CRISPR came from basic research on bacteria.
2. Optogenetics started with a discovery in algae.
3. The GFP protein comes from jellyfish.
The biggest breakthroughs all trace to scientists follow their curiosity. This is one huge reason why we must keep funding basic research!
Bit obsessed by this...Franklin not only recognized the helix but also calculated each turn in spiral—34 Ang—and # of bases per Helix. And yet we have Watson's version where he goes on/on about the right pic (#51) that has no notes v/s left pic (#49) that has extensive notes 1/4
"No wonder Franklin recorded little in her notes about photograph 51..she saw no need to repeat herself. [She] knew exactly what’s in front of her”
science.org/content/article/…?
The main job university admins seem to have is to scrape the Internet for any possible favorable ranking by any random source.
"No wonder Franklin recorded little in her notes about photograph 51..she saw no need to repeat herself. [She] knew exactly what’s in front of her”
science.org/content/article/…?
Subhojit Roy, MD, PhD retweeted
The most important briefings of the day.
Karl Deisseroth, professor of bioengineering and of psychiatry and behavioral sciences, shares the news of his Nobel Prize with his kids.
"Pan didn’t know it at the time but he was racing against research groups across the United States and around the world to put channelrhodopsin into neurons"
scientificamerican.com/artic…
There are worse ways to prepare for a talk #janeliafarms
I remember watching it every week in the 80s
It was so much more interesting to read about Diego Córdoba and Luis Martínez-Zoroa, rather than a stupid machine that spits out numbers.
quantamagazine.org/ai-has-so…
Subhojit Roy, MD, PhD retweeted
So delighted to see our collaboration with the Debelouchina lab at UCSD and the @JeetainMittal group at Texas A&M published in @NatureComms!!
nature.com/articles/s41467-0…
"Wheeling freely in the gaps of human knowledge is this India wicketkeeper batter"
cricinfo.com/story/sl-vs-ind…















