@QuanMed_AI- medical robotics research system by AI and Quantum not big Pharma on @Quan_Chain the only auto-migrating quantum chain. MSc Neuro/AI-Robotics Dev

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Joined September 2022
Unitree released a video yesterday of its new H2-X denting scrapyard cars with kicks & elbows, stepping between a woman & a man with a knife & shoving someone clear of an oncoming car. They're calling it the Kung Fu Legend Guardian. 🦾🦿🤖 The kicks are choreography. The moment worth watching is the backflip off the car roof & specifically the landing. 70 kilograms coming down from roof height arrives carrying about a kilojoule & all of it has to disappear inside one crouch. Absorb it over a quarter of a metre & the legs take close to five kilonewtons - 7 times the machine's own weight -while simultaneously arresting the rotation from the flip, which has to stop at the same instant. Which is why landing is harder than jumping. A motor resisting a fall is being driven backwards; it's a generator. That energy goes either back into the battery through the drive electronics or into the windings as heat & it has to go somewhere inside a couple of hundred milliseconds. It's a thermal & power-handling problem before it's a control problem. Then it's a control problem too. You have the flight time to work out exactly when the foot meets the ground and how stiff every joint should be at that instant. Too stiff & the shock goes through the frame. Too soft & it folds. The energy scales with the height of the drop, so every extra metre makes the same problem harder fast. Which is the thing to watch for in these videos. Jumping is a motor problem and plenty of machines manage it. Landing repeatably, on ground nobody surveyed first, without a tether, is what separates a demo from a product.
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Sophont released a model yesterday that reads which genes a tumour is switching on, from a slide stained with two dyes invented in the 1800s. Hematoxylin binds nucleic acids & turns nuclei blue-purple. Eosin binds proteins & turns cytoplasm & collagen pink. That's the entire chemistry & it's been the default pathology stain for about 150 years - every biopsy taken anywhere gets one. It carries no molecular information whatsoever. It tells you where things are and what shape they are & nothing else. Spatial transcriptomics tells you which genes are being transcribed at which coordinates. It costs thousands per slide, takes weeks & needs tissue handled a particular way from the moment it leaves the patient. Holon-S1 claims to predict the second from the first. Which sounds like reading information that isn't there, except that it is. Expression changes shape. A cell running a proliferation program has a larger nucleus, looser chromatin, a more prominent nucleolus. A tumour recruiting fibroblasts rearranges the stroma around itself in ways that are visible. Morphology is a lossy readout of the transcriptome & pathologists have been reading it crudely for a century - "high grade" means "I can tell from the nuclei that this thing is dividing fast." The model is running that same inference across more dimensions than a person can hold at once. Sophont evaluated it on 16 organ types, more than 15 scanner models, and both FFPE and frozen tissue. In a retrospective osteosarcoma case, a cancer it was never trained on, it flagged a fibroblast program containing FAP - which happens to be the target of the therapy that patient responded to. The limit lives in the word predict. The model infers what expression usually accompanies this appearance. That should hold up well on ordinary tumours & worst on strange ones & strange ones are precisely when someone orders molecular testing in the first place.
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The Navy just quadrupled its contract with Gecko Robotics to $300 million, for robots that crawl around ships measuring how much steel is left. The problem is specific. A carrier deck is covered in non-skid — thick, gritty epoxy that stops aircraft sliding off. To check the steel underneath with a conventional gauge you have to strip it, then put it back, which is most of the cost and all of the downtime. So the condition of the deck stays unknown until the ship is already in drydock and torn open. Ultrasonic thickness measurement works by timing an echo. Send a pulse into the steel, catch the reflection off the far side, multiply by the speed of sound in steel — about 5,900 metres per second — and halve it. A twelve-millimetre plate returns its echo in roughly four microseconds. Coating wrecks that, because the pulse crosses the epoxy twice & nothing tells you which part of the delay belongs to which layer. The fix is to stop timing from the pulse and start timing between two successive back-wall echoes. Both carry the same coating delay, so subtracting one from the other deletes it. You get the steel alone, through the paint, without touching it. What actually changes, though, is the sampling. A technician with a handheld gauge takes readings at marked points - hundreds across a whole ship. Corrosion doesn't distribute itself evenly; it pits & it concentrates at weld heat-affected zones, around drains, under fittings. A sparse grid will quite happily miss the thinnest spot on the hull. A robot that crawls the entire surface takes millions of readings. That stops being an inspection & becomes a map. And once you have the same map twice, the difference between them is a corrosion rate per square inch, which is where you stop finding problems & start forecasting them.
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Most of Earth's heat doesn't come out through land. A square metre of ocean floor gives off 105 milliwatts of the planet's internal heat. A square metre of continent gives off 71. The ocean covers roughly seven tenths of the surface, and the mid-ocean ridge system, where that heat concentrates, runs about 65,000 kilometres, the longest mountain chain on the planet. Every geothermal plant ever built sits on the cooler, smaller share, because that's the part you can drive to. Last month a Seattle company went after the other one. Endurance Energy put a three-ton power plant on an active volcano 300 miles off Oregon, five thousand feet down, and ran it in real time from a room on shore. It produced more power than it consumed for 8.7 seconds, peaking at 16.5 kW. The number that explains the whole effort is sixteen meters. That's how deep they drilled. Enhanced geothermal on land means boring three to five kilometres to reach rock hot enough to be worth anything, then pumping water down and hoping it comes back up. At a mid-ocean spreading centre the heat is already at the seafloor - 281°C fluid arriving under its own convection, no stimulation, no pumping. You aren't drilling to find the resource. You're drilling into something already pouring out. The cold end comes free as well. A land plant rejects its waste heat into the air, which buys you cooling towers, fan loads, water consumption & worse output on hot afternoons. At that depth the seawater sits near 2°C year-round and there is an ocean of it. The hottest ground on the planet is underwater, and until last month nobody had ever taken a watt out of it.
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Viggle AI has released JST-2 today & is calling it the world's 1st full-stack physics-native world foundation model. Joint Space-Time is a successor to the model that earned them a $19M Series A from a16z in 2024. It generates a 3D scene in seconds & expands it in real time, with character motion built in, all from one architecture. Most world models work in pixel & video space; Viggle built the entire stack in 3D instead. That difference sounds like a technicality until you try to add physics. A video model has no chairs in it. Pixel-space world models - the ones predicting each frame from the last - represent a chair as a pattern that keeps recurring. Nothing stores it. Walk out of the room & back & the model regenerates it from context, which is why objects in these systems drift, morph & quietly change shape when something passes in front of them. A physics solver can't do anything with that. It needs objects like mass, position & a contact surface. There is nothing to push on in a field of pixels. So building in 3D isn't an efficiency trick, it's what makes physics expressible at all. Store geometry & the chair is a thing with coordinates - occlusion stops rendering it, not existing. The real-time expansion is the part that follows from the representation. You can extend a scene that exists as geometry, because the room you already made stays where you left it. A video model doing the same walk has to keep re-deriving what's behind you from what it just showed & it has no stake in getting it right twice.
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Anthropic said it would put 5% of its equity into a fund for the public. Musk replied that you should skip the fund & hand the shares straight to people - then said that's what he'd do & pledged one SpaceX share to every kid in America next year. At Friday's close of $146.03 and just over 72 million Americans under 18, that's about $10.5 billion. Musk disclosed a 48.4% SpaceX stake in an August filing, putting the giveaway somewhere near 1% of what he holds. The two approaches differ less than the exchange suggests. Anthropic's own announcement lists direct distributions to specific populations as something the fund might do. SpaceX has already run the play - Gwynne Shotwell pledged a share to each of 2 million Trump accounts in July, which is the obvious vehicle here. What's unsettled is who counts. Musk hasn't said whether "kid" means every minor, only citizens, or only children already holding an account & he hasn't said how or when shares arrive. Anthropic's 5% still needs stockholder approval & the mechanism that grows it - 2% more per 50% rise in company value - is pegged to a baseline they haven't defined yet.
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Musk says it's time for Zelenskyy to go, as Ukraine's war grinds into its fourth year and Kyiv asks Europe for another €70 billion. Zelenskyy blames the fuel price spike on the block in Hormuz, not the war he's fighting. The part nobody's joining up: the same week, Trump waived the tariff law designed to restrict Russian energy exports, and his own party in Congress is furious about it, arguing it directly funds Moscow's war effort. You cannot demand billions more for Kyiv's defence while quietly easing the sanctions regime meant to starve the other side of money. Sovereignty rhetoric only means something if the policy matches it, and right now it doesn't. Who actually wants this war to end, and who's just managing the optics around it?
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Mercedes-AMG revealed its first standalone SUV this week. The top GT 63 makes 1,153 horsepower from three electric motors and takes on 282 miles of range in 10 minutes at a charger. European orders open Monday, US deliveries summer 2027. What makes it work is a motor layout that has been understood for decades & hard to manufacture for just as long. Turn an electric motor on its side and its torque starts scaling with the cube of rotor diameter instead of the square. That's the case for axial flux. A conventional motor is two concentric cylinders with flux crossing the gap radially, outward from the shaft. Make the rotor & stator flat discs facing each other instead, flux running parallel to the shaft, and the active area grows as r² while the lever arm grows as r - widen the disc & torque climbs as r³. In the cylindrical layout the only thing you can stretch is length, which adds force at the same radius. Mercedes got past the manufacturing problem by buying the company that hadn't been beaten by it: YASA, out of Oxford, whose name is the design — Yokeless And Segmented Armature. Delete the stator back-iron and you lose its mass and its iron losses together. Their production motors clear 5 kW/kg and a demonstrator last year hit 42. Lucid's drive unit, among the densest conventional ones in production, makes 16. The charging is the better number though. 710 kW into a 128 kWh pack is a 5.5C peak & the 10-to-80 window averages about 3.5C - 12 minutes. At 800 volts that's roughly 890 amps. Resistive loss goes as the square of current, so pushing the same power at 400 volts would mean 1,775 amps & 4 times the heat in every conductor between the dispenser and the cells. The Cayenne Turbo Electric peaks at 400 kW.
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GPT-6 Astra just broke a German Enigma message that sat unsolved for 85 years. Carter Leffen, a Bloomberg product coach with no cryptography background, picked an unsolved cipher off Frode Weierud's Crypto Cellar Research site, nudged the model a few times, went to bed. By morning it had the plaintext. Enigma's rotors and plugs could route the alphabet up to 103 sextillion ways. That complexity was the whole point, only trained specialists with purpose-built kit were meant to touch it. Elonka Dunin, who wrote the standard references on this, is now fielding a deluge of false positives from people who, in her words, "don't really understand cryptanalysis." Read that the other way round. Cryptanalysis was never impossible, it was expensive and gatekept, and the credentialing made it look sacred. A free evening and an open model did what institutions couldn't manage in eight decades. If a hobbyist with a chat window can do this to Enigma, what exactly are governments still betting on when they talk about controlling who's allowed to use AI for cryptography?
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Four Gemini 4 Argon agents beat Minecraft in 27 hours & 14 minutes. They never saw the game. No pixels, no keyboard. The agents wrote JavaScript against the Mineflayer library & read back text for position, inventory, error messages. Minecraft as an API, not a screen. That changes what the achievement is & the authors say so themselves. Mineflayer hands you exact coordinates & built-in pathfinding, so the things that make Minecraft hard for a person like seeing, aiming & finding your way back, are all function calls here. What's left is planning across 27 hours, dividing work between four agents & debugging your own code when it breaks. It broke constantly. 2,783 programs written before the win, 22% of them ending in errors. 605 deaths. The server restarted 6 times. 😂 The End fight alone ran nearly 14 hours where more than half the total run was the final boss. Coordination was 229 chat messages & a shared memory file. Nobody assigned roles; they sorted it out between themselves, one handling food and supplies, another making tools, recovering each other's dropped items after deaths. A fifth agent watched the entire run & never played. Java Edition 1.20.4, survival, Easy difficulty, random seed, cheats disabled. The authors call it the first end-to-end autonomous completion of Minecraft by AI agents & note it's a single run, so it says nothing yet about how reliably it repeats.
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Ledger's new device separates the display and touch controls from Android entirely. That isn't a coincidence of timing. 5 days ago Ledger Donjon published how the CryptoBilis implant worked: a microcontroller inside the enclosure reads the recovery phrase off the screen during setup and transmits it over LTE through an embedded SIM. It never touches the Secure Element, the OS, or the signatures. It reads the display. Atom, announced Wednesday in Paris, runs AOSP alongside an EAL6+ Secure Element running Ledger's own OS, with screen & touch input wired to the secure side rather than the Android side. Signing happens in Secure Mode, where Android can't reach it. Sold only through Ledger's own site, with tamper-evident features that reveal whether the enclosure has been opened. The policy changes matter as much as the hardware. Resellers must now keep devices off shelves until purchase, and returned units can't be resold at all. That second rule closes the vector directly as Ledger says a criminal group bought genuine devices, modified them & sent them back. Cost: $849 to reserve a Founders Edition on a $100 refundable deposit, $899 regular, estimated delivery Q2 2027. Still in development & Ledger says specs & price may change. Loss estimates keep climbing. Yfarmx now traces roughly $103.4 million across 530 addresses. Ledger still hasn't confirmed a total.
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Tesla ran a Roadster up a halfpipe last night & flipped it in mid-air. The number that explains it is 80 kilonewtons of thrust. The car is around two tonnes, so roughly 19.6 kN of weight. The thrusters are putting out about four times what the car weighs. For scale, a Falcon 9 leaves the pad at a thrust-to-weight ratio near 1.4. A fighter jet in afterburner is barely above 1. It's cold gas, not combustion, so that’s air or nitrogen at about 10,000 PSI in a composite-overwrapped tank sitting where the rear seats would go, 260 kg of it, vented through nozzles around the body. No fuel, no flame & an onboard compressor refills it. The constraint isn't energy, it's how long the tank lasts. The upside-down driving is a separate trick and arguably the better one. Aerodynamic downforce scales with the square of speed, so a wing gives you nothing when you're slow. The Roadster uses suction fans instead, actively pulling air out from under the car, which works at any speed including zero. Musk claims over 2 G of cornering grip from it. That idea has a history. Chaparral's 2J ran fans in 1970. Brabham's BT46B won its only race in 1978 & was withdrawn immediately afterward. Production is now 2028 which is the sixth date since the car was announced in 2017. The demo car was remote-operated & the FAA treats anything that leaves the ground as an aircraft, so there were airspace restrictions over McGregor last night.
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Amazon's Bee launched yesterday at $74.99. It's a wrist-worn microphone that listens all day & turns your conversations into summaries & to-do lists. The privacy engineering is better than you'd expect. Bee Private Compute processes raw audio in real time inside an isolated environment and then deletes it, keeping only an encrypted text transcript. The encryption keys are generated & held on your own device. Amazon says it has no master key. That's a genuinely good design & it protects exactly one person in the room. Everyone else is an input. They can't read the transcript, can't delete it & can't switch the thing off, only the wearer can. There's an LED for active listening, which assumes a stranger knows what a Bee is & what its light means. The threat model has one principal & it isn't the person across the table. Specs: IP67, 7 days per charge, dual mics with noise filtering. The $99.99 Eclipse magnetically attaches to your phone & runs 21+ days. Amazon's reviews include buyers saying it's illegal to record people without permission. Mostly it isn't. Federal law & 37 states plus DC are one-party consent - if you're part of the conversation, you can record it. 13 states require everyone's. Bee has a better argument than that, too. It doesn't keep audio. Wiretapping statutes are written about intercepting oral communications & a device that transcribes & then deletes is legally closer to taking notes than to recording. That's more untested ground, not settled illegality. Which is the actual problem. Nobody objects to you taking notes because your memory is lossy & your handwriting is slow. What makes a transcript different isn't that it's illegal. It's that it's complete.
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Rhoda AI showed a robot retrieving objects with its cameras covered, using a new tactile sensor that reads pressure, texture, vibration, slip & temperature. Slip is the one on that list doing the real work. When you lift a glass you don't calculate how hard to hold it. Your skin detects micro-slips at the contact surface like tiny shear events, usually with a vibration signature & grip force rises automatically. Johansson & Westling measured that reflex at 74 milliseconds, about half the time it takes to change your grip on purpose. Three afferent types carry the signal: FA I, FA II & SA I. It's a closed loop running underneath conscious control, and it's why you can pick something up in the dark without crushing it or dropping it. Vision tells you where an object is. Touch tells you whether you're losing it. Rhoda's Direct Video-Action model runs on a similar cadence: observe, predict the next state as video, act, observe again, every few hundred milliseconds. Putting touch inside that loop gives the prediction something to correct against when the camera can't see the contact point. In a real grasp, the gripper is occluding the contact point almost by definition.
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About 5% of rare diseases have an approved treatment. There are somewhere between 7,000 & 10,000 of them, affecting more than 30 million Americans. The FDA launched something today aimed at that gap & the interesting part is statistical. A conventional trial works by making the sample large enough to rule out chance at a set threshold. That's the entire machinery - a power calculation tells you how many patients you need to detect an effect of a given size at p<0.05. For a disease with 200 known patients worldwide, there is no n that satisfies the equation. The trial fails before it begins & it’s not because the drug doesn't work. The Rare Disease Framework Initiative names Bayesian designs as one answer. Instead of asking whether you can reject a null hypothesis, a Bayesian trial asks what the probability is that the treatment effect exceeds some threshold, given a prior & the data in hand. That permits things a frequentist design can't like formally borrowing information from natural history studies, updating continuously as patients enroll & reporting uncertainty as a distribution rather than a verdict. The rest of it is risk-based manufacturing & inspection review, patient and caregiver testimony formalised as structured data at milestone meetings, more outside expertise brought into reviews. Amy Comstock Rick's Rare Disease Innovation Hub is running it. First public meeting is October 28 at White Oak.
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A Falcon 9 lifted off from Cape Canaveral yesterday at 6:35am, carrying 6,300 pounds of cargo to the Space Station. 🚀 For about half an hour afterward, people from Florida to the Carolinas watched a beautiful glowing jellyfish hang in the sky above them. 🪼 That jellyfish is a picture of how thin the upper atmosphere is. At sea level a rocket's exhaust plume stays tight - the surrounding air pushes back & holds it in a column. Climb high enough & that back-pressure actually disappears. The same exhaust leaving the same nozzle spreads outward hundreds of times wider, because there's nothing left to confine it. The bell shape in the photo is that expansion, drawn to scale. What you're seeing is ice. Falcon 9 burns RP-1 and liquid oxygen, so the exhaust is mostly water vapour & CO₂. In the cold of the upper atmosphere the water freezes into a cloud of micron-scale crystals & those crystals scatter sunlight. The sunlight is the other half of it. At 6:35am the ground was still inside Earth's shadow, but the rocket had climbed above the shadow line into direct sun. Lit cloud, dark sky behind it. An hour later the sky would have been too bright for any contrast. An hour earlier there'd have been no light on the plume at all. Even the colours are doing work. The blue-white up top is sunlight scattered more or less directly. The orange lower down is light that took a longer path through the atmosphere to get there & lost its blue on the way which is the same reason sunsets are red. 🌅 A cloud of frozen engine exhaust, lit from below the horizon.
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Gemini 4 Argon watched a video of someone playing cornhole & then taught a humanoid to do it. The pipeline runs video to sim to real. Argon takes the footage, maps the environment, works out the person's joint movements & then writes the simulation code itself - a calibrated MuJoCo model of the scene and the throw. Inside that simulation it runs more than 4,500 domain-randomized episodes, varying frictions, masses and timings so the policy learns something robust instead of something tuned to one exact setup. The finished policy goes to Apptronik's Apollo humanoid, which sank seven throws in a row its first time in the real world. Sim-to-real transfer has worked for years. What slowed it down was that a person had to build the simulator - model the geometry, tune the physics, write the training environment. Argon did that from a video. Google's framing is weeks to hours. That's the part it's compressing.
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Apple's new home display identifies who's standing in front of it and rebuilds its interface for that person. It also, periodically, makes you go unlock your iPhone. Those two facts together are the design. Recognition & authentication are different problems & they're being handled by different devices. Identifying someone means matching a face against a small set of known household members & picking the closest. The cost of getting it wrong is showing your brother your calendar. Authenticating someone means proving identity against something actively trying to defeat you with a photo, a video, a sibling who looks like you, a mask. That needs depth, liveness detection & a far lower tolerance for false accepts. HomeView does the first from across a room & hands the second to a device you're holding. The periodic iPhone unlock isn't friction Apple failed to design out. It's the authentication step, relocated to hardware that can carry it. For the record: 7-inch square Liquid Retina, 500 nits down to 0.3, A18 chip, 12MP camera with Center Stage has no physical buttons. $299 for either the tabletop or wall-mounted version, shipping November 13.
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Octopus intelligence was never explained by gene count. A paper out this week points at something stranger - the shape the genome is folded into. A gene's control switches can sit hundreds of thousands of bases away on the linear sequence. They work anyway, because DNA loops and brings them into physical contact with the gene they regulate. Distance along the chromosome isn't distance inside the nucleus. Which switch reaches which gene is a question of folding. Hundreds of millions of years ago the coleoid genome like octopus, squid & cuttlefish - went through a burst of reorganization that threw distant chromosome regions together. New contacts, new regulatory reach. Over evolutionary time those contacts hardened into interconnected networks the authors call "regulatory entanglement." The measurement that carries it is the large chromatin domains held steady across species. The finer loops didn't. Those varied by species, by tissue, by developmental stage & they clustered near genes tied to cephalopod traits, nervous system genes among them. The stable architecture stayed put. The flexible layer did the evolving. This means a genome can invent new expression patterns without touching the essential machinery underneath. Same parts, rewired.
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12 days ago Tennessee tried to execute Christa Pike. Witnesses say staff closed the curtain, administered a second dose out of sight & escorted everyone out while she was still breathing. The state still hasn't explained what went wrong. On December 3, the Pentagon plans to put an execution on a livestream. Nidal Hasan - the former Army psychiatrist who killed 13 people & wounded 32 at Fort Hood in 2009, is scheduled to face a firing squad at 1pm that day. Pete Hegseth recommended the method & says the public will be able to watch. Pentagon spokesman Sean Parnell says Trump approved it, though Trump said Saturday he'll make the final call on the broadcast himself. The markers worth knowing: No US military execution since 1961. No military firing squad since Private Eddie Slovik in the Second World War. No public execution anywhere in America since 1936, when Rainey Bethea was hanged in Kentucky in front of a crowd estimated at 20,000. Pope Leo XIV, who is American, posted Saturday that the death penalty is "inadmissible because it is an attack on the inviolability & dignity of the person." Cardinal Pietro Parolin called the broadcast plan "truly incomprehensible." Archbishop Paul Coakley of the US bishops' conference called it a "barbaric promotion of a culture of death." Two executions, about two months apart. One the state won't let anyone see into. One it intends for everyone to watch.
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