The West Lab @TheCrick studies mechanisms of DNA Recombination and Repair. Tweets by lab members, unless signed SCW. Views are own

London
Joined December 2022
The West Lab retweeted
Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳 Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m
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We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home…
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📣#RECOMBINATION25 PROGRAMME NOW LIVE! Exciting news! The first draft of the programme for the 2nd Recombination Mechanisms conference is now available. 🌟 🗓Important Deadlines: Early Bird & Talk Submission – 28 Nov 2024 Poster Submission & Registration Deadline – 13 Mar 2025 Don’t miss out—check out the programme and get all the details here: bit.ly/4ekGnMz
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Delighted to share that my manuscript of "Mechanism of single-stranded DNA annealing by RAD52-RPA complex" is now in Nature!
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s41586-0…. Thread ⬇️⬇️⬇️ (1/8)
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We awarded our annual Translation Prize last night, recognising researchers at the Crick who are applying their research in a real-world setting. Congratulations to our winner Anaid Benitez, runner-up Andreia Bernardo and all the nominees! 🏆🎉crick.ac.uk/news/2023-10-13_…
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The West Lab retweeted
A recent publication on Nature showed new DNA repair mechanism uncovered by the @Francis Crick Institute with C-Trap, proving RAD51 paralogs as crucial as the BRCA2 pathway in cancer prevention. Learn more about it: bit.ly/3DukiLq
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The #Recombination23 Poster Session is in full swing and what wonderful weather we have for it… 🧬☀️
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The West Lab retweeted
Looking forward to the start of the @Fusion_Conf Recombination Mechanisms conference in Portugal. Awesome location and speakers. Best meeting of the year for sure! Thanks @SCWestLab
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The West Lab retweeted
🧬 Breakthrough in DNA repair and cancer research! The team at @TheCrick has used C-Trap to explore the RAD51 paralogs which are in the same pathway with BRCA2.
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In a collaboration between @SCWestLab and @BoultonLab, published in @Nature, researchers made key findings about a protein complex needed to repair damaged DNA and protect against cancer, which could one day help develop better targeted cancer treatments. ow.ly/wF0w50OTZkm
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The West Lab retweeted
A breakthrough in DNA repair research! @SimonBoulton and @StephenWest at @TheCrick has used #C-Trap technology to explore the BCDX2 complex. This could lead to new therapeutic strategies for diseases linked to RAD51 paralog complex mutations. Check here: go.nature.com/3PoCTzC
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Just had amazing visits to LUMICKS, NKI, the Crick, and UCL, thanks to my exceptional LUMICKS hosts: Andrea Candelli, Jos Maas, and Nina Brett-Pitt. What an extraordinary trip! Dankjulliewel.
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Today our important study on air pollutants in the promotion of lung cancer has been published in @Nature led by @WillHilliam @LimEmilia @DrClareWeeden @SwantonLab ...Thread below🧵nature.com/articles/s41586-0…
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Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. doi.org/10.1016/j.molcel.202…
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The West Lab retweeted
Our new cryo-EM structure explains how the MRN complex can act both as DNA double-strand break sensor & DNA tethering device, read the paper here: authors.elsevier.com/c/1gK10… Huge thanks to all collaboration partners W.Roos, B.Steigenberger and C. Junge! #cryoEM, #DNArepair, #MRN
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Postdoctoral positions available in Nussenzweig lab to study mechanisms involved in DNA repair- 1st position (wet lab) focuses on using cutting-edge cellular, molecular, and genomic tools. 2nd uses computational approaches to study DNA repair.
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Merry Christmas from everyone at the Crick! 🎄✨❄️
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