Scientist; mostly separations and MS, development of technologies (e.g. SLIM IM-MS), and their applications in proteomics, metabolomics, lipidomics....pan-omics
PNNL, Richland, WA, USA
Joined January 2010
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Richard D. Smith retweeted
Excited to announce that the Purdue Board of Trustees has approved my promotion to Associate Professor, effective this August. Thank you to friends, collaborators, #teammassspec members for your incredible support of my career so far!! purdue.edu/newsroom/purdueto…
Separation and Characterization of Synthetic Cannabinoid Metabolite Isomers Using SLIM High-Resolution Ion Mobility-Tandem Mass Spectrometry (HRIM-MS/MS) | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/jas…
Richard D. Smith retweeted
I’m proud to have contributed to the @JProteomeRes Special Issue Women in Proteomics and Metabolomics!
Our work is a step forward to fully automated quantitation of isomeric proteoforms in top-down proteomics:
doi.org/10.1021/acs.jproteom…
@EMSLscience
@PNNLab
Richard D. Smith retweeted
ISIMSers! See more info about early career event from isims.info/early-career/earl…
Separation and Characterization of Synthetic Cannabinoid Metabolite Isomers Using SLIM High-Resolution Ion Mobility-Tandem Mass Spectrometry (HRIM-MS/MS) | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/jas…
Mobility Selective Ion Soft-Landing and Characterization Enabled Using Structures for Lossless Ion Manipulation | Analytical Chemistry pubs.acs.org/doi/10.1021/acs…
My last day at PNNL before retirement. A great place to have spent 47+ years with a career centered around MS, separations, and their many applications. May engage in a few consulting etc. activities, but VERY selectively….and I guess at least one more Annual ASMS meeting!
Space charge can be our friend; ion separations in large ion populations as a basis for e.g., industrial scale ion processes. Accumulation of Large Ion Populations with High Ion Densities and Effects Due to Space Charge in SLIM IMS-MS pubs.acs.org/doi/10.1021/jas…
Accumulation of Large Ion Populations with High Ion Densities and Effects Due to Space Charge in Traveling Wave-Based Structures for Lossless Ion Manipulations (SLIM) IMS-MS | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/jas…
Investigating Performance of the SLIM-Based High Resolution Ion Mobility Platform for Separation of Isomeric Phosphatidylcholine Species | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/jas…
Richard D. Smith retweeted
Curious about what SLIM ion mobility can do for your separations?? Be on the lookout for an upcoming paper from Selena, showing the benefits of @MobilionSystems SLIM technology for clinical analysis including Vitamin D metabolites!
A significant contribution towards enabling new SLIM capability developments from the Clowers Lab: SLIM Tricks: Tools, Concepts, and Strategies for the Development of Planar Ion Guides | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/jas…
A detailed computational dive into the Role of Ion Rotation in Ion Mobility: Ultrahigh-Precision Prediction of Ion Mobility Dependence on Ion Mass Distribution and Translational to Rotational Energy Transfer. Bottom line: rotation matters. pubs.acs.org/doi/10.1021/acs…
Richard D. Smith retweeted
Terrific session on ion activation/dissociation organized by @SLIM_technology honoring the career of Jean Futrell and celebrating his 90th birthday in 2023. Wonderful talks, highlighted by Dick Smith and @LabLaskin . Great to see all of Jean’s friends @asmsnews #ASMS2023
Richard D. Smith retweeted
Happy to share our new #python tool LipidOz for determining lipid double bond positions from OzID data. #opensource #automation #deeplearning Feel free to share and test it out! @CommsChem #TeamMassSpec disq.us/t/4fub0vk
A blast from the past; a Perspective/Account stimulated by all the exciting progress being made by CDMS Individual Ion measurements.
Large Individual Ion FTICR Measurements from the Mid-1990s Using Reactions for Charge Determination Mass Spectrometry pubs.acs.org/doi/10.1021/jas…
One reason I wrote this was the mostly forgotten and unexpected observation of charge state increases; something unlikely to be observed with a population of ions. Individuals are hardly ever avarage!
pubs.acs.org/doi/10.1021/jas…
Richard D. Smith retweeted
Seeing the book's cover reminds me of the original artwork created by Marianne Wendeborn. Derived from the first intact analysis of a virus with mass spectrometry. Nice memories. onlinelibrary.wiley.com/doi/…
Thanks so much @kadzuis for mailing the book! I received it this morning. I feel super excited and can't wait to learn more about mass spectrometry!
Richard D. Smith retweeted
Don't miss out on @Pittcon March 18-22. Join us 3/22 2:45-3:20pm to hear from @ChouinardLab @clemsonuniv as they share their innovative insights on High-Resolution Ion Mobility Approaches for Small Molecule Analysis. Symposium details: hubs.ly/Q01HqhWj0 #TeamMassSpec #SLIM
A truly impressive work from the Rizzo Laboratory using a SLIM-based multistage IMS-CID technique combined with cryogenic IR spectroscopy for glycan analysis pubs.acs.org/doi/10.1021/jas…
