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Thank you Paul and the ENIGMA team for your incredible support in getting this off the ground! Excited for its future :D
💡HOW DO #MEDITATION, Mindfulness, + Contemplative Practices affect your Brain ?
👉55 sites studying meditation with brain imaging published ENIGMA-Meditation's [1] first paper, out today ! sciencedirect.com/science/ar…
[1] a very chill group, see pic ;)
💡join us ! enigma.ini.usc.edu/ongoing/e… Congrats 🪩🎉Saampras Ganesan + Team !
@SaamprasG @sofievalk @enigmabrains @MatthewSacchet @vdcalhoun @NegarFani @njahanshad @ruchikaprakash @dave_vago @AndrewZalesky
**The goal of ENIGMA-Meditation is to systematically and reliably characterize the neuroscience of different meditation practices, evaluate commonalities and distinctions between diverse practice forms and stages, and investigate how their neuroscientific substrates relate to psychological, physiological, clinical, and cognitive outcomes. Traditionally, meditation practices were deeply rooted in cultural, religious, and philosophical contexts, primarily focusing on spiritual growth rather than treating mental or physical conditions or enhancing mental capacities. While ENIGMA-Meditation also seeks to explore the neuroscience of meditation within such traditional contexts, the focus of the current paper is primarily on the neuroscience of contemporary, secular adaptations of meditation practices and their benefits on health and well-being. [from the paper]
💡"Meditation encompasses contemplative mind-body practices characterized by diverse techniques, philosophies, and religious traditions ... Broadly, meditation involves purposeful attention, voluntary regulation of psychological and embodied processing, and modulation of conscious awareness ... Meditation practice can enable salutary psychological, psychosomatic and/or spiritual states of consciousness with acute and enduring positive impacts on mood, cognition, and general well-being ... Scientific investigations of meditation have predominantly involved techniques including mindfulness (e.g., present-centered focus with non-judgemental observation of experience), focused attention (e.g., sustaining breath-focused attention), open-monitoring (e.g., continuous, effortless monitoring of experiential content), loving-kindness (e.g., sustained repetition of benevolent thoughts), compassion (e.g., sustained generation of compassionate feeling), mantra (e.g., focus on repetition of a mantra), non-dual awareness (e.g., awareness of awareness, transcending subject-object duality), and their variations..." from sciencedirect.com/science/ar…

ALT ENIGMA- Meditation - a newly established innovative global consortium for collaborative neuroimaging of meditation that will aim to address existing challenges and deepen the neuroscientific understanding of meditation. ENIGMA-Meditation brings together neuroimaging data from meditation researchers worldwide to facilitate large-scale meta- and mega-analysis projects using shared, strategically-planned, standardized processing and statistical analyses.
Saampras Ganesan retweeted
🔥 IT'S A WRAP !!! ENIGMA's 2025 End-of-Year VIDEO GUIDED TOUR ( youtube.com/watch?v=C0GJUc24… ) summarizes global progress tackling 30+ brain disorders by 2,000+ scientists across 45 countries, using neuroimaging, brain mapping, genomics, environmental assessments, drug treatment, neurostimulation, disease staging + prevention across cultures - uniting scientists worldwide in a common quest to understand brain diseases.
🔥 PLEASE JOIN US to celebrate this year's major discoveries, highlighting new leads across dozens of brain diseases + disorders (please share):
🎇 VIDEO: youtube.com/watch?v=C0GJUc24…
🎇 PDF: drive.google.com/file/d/1-uF…
🎇 Hi-Res Photo: drive.google.com/file/d/1qgx…
🙏We started our call with a few words of appreciation and gratitude for our friend and colleague, Professor Dan Stein, who tragically passed away earlier this month. He was a giant among men - he helped to make ENIGMA what it is, championed the cause of global health worldwide - he was and is everywhere all the time for everyone, proud of his trainees, creating opportunities, caring for patients, encouraging and guiding the next generation in his calm and memorable way.
🙏Thank you to Odile van den Heuvel, Nic van der Wee and Nynke Groenewold for sharing their thoughts, also on behalf of ENIGMA's OCD, Anxiety, HIV, ENIGMA-Africa, and the University of Cape Town leadership teams, including @bas_janna Aliaa Ibnidris, Kimberly Blake, Christine Lochner, Freda Scheffler, Jonathan Ipser, Allegra Moodley, @FaraiMberi , Emmanuel Nwosu, Sarah Jacobs, and Vicki Deliperi.
🙏 A BIG thank you to @njahanshad @LSalminen @KE__Lawrence @JulioVillaln1 @Frangougroup Ysbrand van der Werf @saffetgonul Cagdas Eker Rebecca Knickmeyer Delin Sun Fernando Cendes Joaquim Radua Miquel Angel Fullana Rivas Theo van Erp Jessica Turner Ole Andreassen @lianne_schmaal Janita Bralten Shan Hannah Luo Bearden Carrie @JacquemontSeb @ClaraMoreau9 @HippocampusGirl @DrEmilyD Amanda Boyes, Tim Hahn Tim Silk @SaamprasG Tonya White Tiril Gurholt Sook-Lei Liew Andrei Irimia @KCaeyenberghs @likeajumprope Andre Altmann @NeilOxtoby John Van Horn @_brainstorm_12 @BramshQ @vdcalhoun @TownendSophie @DrJamesBooth @FangChengYeh @KeckMedicineUSC @USCLONI @kkumar_iitkgp @USCLONI @USC @RuiyangGe @shalailahaas @enigmabrains
Saampras Ganesan retweeted
7 Tesla fMRI neurofeedback enhances meditation training in novice mediators
A colossal effort by @SaamprasG to set up the study, with help from @vale_addiction Nick Van Damme, Brad Moffat and many others
link.springer.com/article/10…
Saampras Ganesan retweeted
Can brain training improve #meditation? 🧘♂️
New study lead by @SaamprasG featuring AddPro's @vale_addiction suggests that #neurofeedback can boost awareness + reduce emotional distress during meditation in beginners!
full text: link.springer.com/article/10…
Congrats to all authors!
Glad to share that my PhD's final paper is finally out in @SpringerNature Mindfulness.
link.springer.com/article/10…
7 Tesla fMRI neurofeedback training enhances meditation training and real-world practice for beginners.
Brief summary in 6 comments below~
5) Importantly, this study led to the establishment of the first 7T fMRI neurofeedback facility in Australia.
6) Huge thanks to my supervisors, collaborators and others that helped throughout! ~ @AndrewZalesky @themoff @vale_addiction @ntvandam @sunjeevk @MatthewSacchet @masaya_misaki Aki @RebeccaGlarin @MBCIU_UoM @ContemplateUoM
Saampras Ganesan retweeted
🔥AMAZING TO SEE everyone @ last night's ENIGMA @OHBM party here in Brisbane, Australia !!! 🥂🎆🎈🥳
🔥take 1
🔥take 2 (without motion correction ;)
#OHBM2025
@enigmabrains @ENIGMA_Diabetes @OHBM
@OHBM_Trainees @OHBM_Australia @OhbmOpen @enigmabrains @ENIGMA_Diabetes @USCLONI @USC_LoBeS @USC @KeckMedicineUSC @sofievalk @ClaraMoreau @njahanshad @DrEmilyD
@AI4AD @misicbata @kkumar_iitkgp @minjeongyun5 @bas_janna @NeilOxtoby @Kangjoo_Lee_ @ycgyan @sofievalk @Frangougroup @KCaeyenberghs @zuoxinian @lianne_schmaal
Saampras Ganesan retweeted
🎉Celebrity neuroscientist sightings @OHBM 🔥
1⃣Sylvia Lin, Amanda Boyes, Tim Silk, PT; PT, Saampras Ganesan, Tonya White; PT, Neda Jahanshad, Sophia Thomopoulos, Chris Ching;
2⃣ PT, Tiril Gurholt, Suyi Ooi; PT, Kami Pearson, Lei Wang, Habib Ganjgahi; PT, Shan (Hannah) Luo; PT, Juan Fernandez Ruiz;
3⃣ PT, Jiyang Jiang, Andrei Irimia, Shan Luo; PT, Karen Caeyenberghs; PT, Boris Gutman, Violeta Céspedes Izquierdo, Tracy Melzer, Emile d’Angremont;
4⃣ PT, Habib Ganjgahi; PT, Laura Han, Philipp Sämann, Chao-Gan Yan; PT, Johanna Bayer;
5⃣ Philipp Sämann, Johanna Bayer, Lianne Schmaal, Laura Han, PT; PT, Johanna Bayer, Emily Dennis, Andre Altmann, Neil Oxtoby
#OHBM2025
@NeilOxtoby @likeajumprope @lianne_schmaal @DrEmilyD @SylviaCLin @SaamprasG @ycgyan @KCaeyenberghs @njahanshad @enigmabrains @ENIGMA_Diabetes @OHBM_Australia @OHBM_Trainees
Saampras Ganesan retweeted
Congratulations to Dr. Saampras Ganesan for completing his PhD! 👏
Dr Ganesan’s research saw him establish a neurofeedback system for the 7T MRI scanner and develop an innovative model to train beginner meditators.
Well done @SaamprasG ! 🎉
#PhDGraduation #MeditationResearch
Saampras Ganesan retweeted
Science has a hypothesis-testing part, but it has an equally crucial ‘night science’ mode, where new ideas are improvised for the first time.
Saampras Ganesan retweeted
Replying to @HopfieldJohn
@HopfieldJohn and @geoffreyhinton, along with collaborators, have created a beautiful and insightful bridge between physics and AI. They invented neural networks that were not only inspired by the brain, but also by central notions in physics such as energy, temperature, system dynamics, energy barriers, the role of randomness and noise, connecting the local properties, e.g., of atoms or neurons, to global ones like entropy and attractors. And they went beyond the physics to show how these ideas could give rise to memory, learning and generative models; concepts which are still at the forefront of modern AI research.
Their ideas inspired me so profoundly that I decided to choose learning in neural networks for my own research as a graduate student. They motivated me to look for abstract principles that could be as simple as the laws of physics, but could explain biological as well as artificial intelligence. I'm truly delighted for them and for our field.
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Physics to John J. Hopfield and Geoffrey E. Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”
Saampras Ganesan retweeted
Very excited to share that our 6-site mega-analysis of functional connectivity changes in youth MDD(n=810) is out now in Nature Mental Health (tinyurl.com/mv889hsm) and featured on Research Briefing and the Guardian!
Are brain changes in youth MDD the same as those in adults?
What happens in your brain when you meditate?
An article that explains this in simple, easy-to-understand language, perfect for kids aged 10 and up.
Most importantly, this has actually been peer-reviewed by students aged 10 and up! 😎
lnkd.in/gf7PyHNp
New article alert!📢Feeling constantly distracted by your thoughts and feelings? 🧠 Research shows that practicing meditation can help us regain focus and manage distractions. More info here bit.ly/4cmYWyA @SaamprasG @ntvandam BradMoffat @vale_addiction @AndrewZalesky
Saampras Ganesan retweeted
This is super important for anyone using psychedelics to understand going in. Psychedelics reliably produce the *feeling* of insight. Doesn't make it true. Please read before disowning your family after that ayahuasca retreat.
nature.com/articles/s44271-0…
Thrilled to have delivered my first in-person conference talk and seen through the symposium on advancements in neurofeedback to advance translation at @OHBM !
Hearty thanks to @AndrewZalesky for always being an extremely supportive mentor!
























