
Dieter Saur lab | pancreatic cancer & colorectal cancer research | @TranslaTUM/Klinikum rechts der Isar | account run by Saur lab members
München, Bayern
Joined March 2021
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We welcome @ChiaraFalcomata, who started her new position as junior research group leader at DKFZ today. Her research focuses on how pancreatic cancer evades the immune system and adapts to therapy, with the aim of restoring anti-tumor immunity and improving treatment responses.
Nature research paper: A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion
go.nature.com/4r3Zwdv
Saur Lab retweeted
Pulling out all the stops vs pancreatic cancer.
The recent FDA-approved, celebrated drug daraxonrasib, increased median survival by 6.5 months @RevMedicines
That's a positive step but clearly not enough. This new @Cancer_Cell paper lays out a path for more.
cell.com/cancer-cell/fulltex…
Saur Lab retweeted
Excited to share our story on how SERPINs orchestrate local immunosuppressive niches in PDAC. Now out @Nature !
Spearheaded by @ChiaraFalcomata
@Brown_lab1
@MiriamMerad
@IcahnMountSinai
@SinaiImmunol
nature.com/articles/s41586-0…
(1/n)
Saur Lab retweeted
Cancer-derived SERPINE1 and SERPINB2 are local spatial organizers of immune suppression @Nature @IcahnMountSinai @ChiaraFalcomata @SinaiImmunol
nature.com/articles/s41586-0…
Saur Lab retweeted
Pancreatic tumors are highly heterogeneous and immunosuppressive. But is immune resistance imposed across the whole tumor - or built locally by distinct cancer-cell states?
I’m incredibly excited to share our new paper, now out in @Nature! 🎉
doi.org/10.1038/s41586-026-1…
(1/7)
Saur Lab retweeted
Amazing news today, culmination of years of research & clinical trials in #PancreaticCancer.
The @RevMedicines approval for Rasonque (Daraxonrasib) will open many doors, including other inhibitors in this space & combinations. @OncoAlert @KRASKickers
fda.gov/news-events/press-an…
Honored to receive an #ERC Advanced Grant! EvokePDAC will reveal how #PancreaticCancer evades immunity and combine myeloid reprogramming with RASi to trigger antitumor immunity. Thanks to our team & collaborators! PhD & postdoc positions available—apply! erc.europa.eu/news-events/ne…
🚀 Excited to share Cellpin for #SpatialTranscriptomics! Led by P. Putze & D. Lucarelli with @fabian_theis. Outperforms 6 methods for gene prediction, scales to atlas-size references, and boosts cell-state resolution in full-transcriptome Atera data. doi.org/10.64898/2026.06.02.…
Saur Lab retweeted
EMA fast tracks review of a medicine for metastatic #PancreaticCancer
The medicine, no surprise, is Daraxonrasib.
ema.europa.eu/en/news/ema-fa…
Saur Lab retweeted
It was such a great conference-so much that patients families Need to know about keen to help them understand what this might mean for them there is so much Hope for better outcomes for a better future #sethslegacy
Saur Lab retweeted
The @CR_UK #PanConf26 was proof how much great science is happening in #PancreaticCancer in the UK & rest of Europe. Now is the time for greater international collaborations with our partners across the Atlantic. Really enjoyed my time in London!
Thanks to @BristiBasu8 for 📸
Saur Lab retweeted
The inaugural #CRUK #PanConf26 may be over but I suspect it will not be the last one…😉
And this is thanks to all the people that made this happen, especially @TaraMcKay20, our 350+ attendees (>60% from outside the UK) and my wonderful co-organizers @Aiims1742 and @SaurLab!
Saur Lab retweeted
Ready to start Day 2 of the inaugural @CR_UK #PancreaticCancer conference!
Thanks to co-organizers @BiffiGiulia & @SaurLab, and the @CRUKresearch team for putting this wonderful meeting together. The conference hashtag is #PanConf26
@TaraMcKay20 @lgoodbu
Saur Lab retweeted
Wow! Standing room only!
Amazing to see the full house at the inaugural @CR_UK #PancreaticCancer meeting. @ciacobu delivering her keynote lecture. Thanks to all the attendees for their enthusiasm.
@BiffiGiulia @SaurLab @TaraMcKay20
🎉 Day 1 of the inaugural #CRUK #PancreaticCancer conference is here 🎉
Thank you to @Aiims1742 @SaurLab @TaraMcKay20 and our session chairs for help shaping a fantastic programme!
Saur Lab retweeted
🎉 Day 1 of the inaugural #CRUK #PancreaticCancer conference is here 🎉
Thank you to @Aiims1742 @SaurLab @TaraMcKay20 and our session chairs for help shaping a fantastic programme!
Saur Lab retweeted
The overall survival curves for Daraxonrasib in 2nd line advanced #PancreaticCancer leave no doubt how impactful this advance is for the field & for patients. Congratulations Brian Wolpin, @EileenMOReilly & @md_oberstein et al.
A seminal #ASCO26 plenary!
nejm.org/doi/full/10.1056/NE…
Catalogue entries for more than 100 antibodies sold by the research services and supply company Thermo Fisher Scientific contain images that have apparently been manipulated, according to a pair of science sleuths.
go.nature.com/4wZqGEE
Saur Lab retweeted
🎉 Very happy to have had the opportunity to contribute to this latest @DiseasePrimers #Review on #PancreaticCancer together with a number of great colleagues! @ednacukierman @EileenMOReilly @SaurLab @BarbaraGrnwald ...
Hope it is a useful read! 😊💜
nature.com/articles/s41572-0…
Saur Lab retweeted
Phoenix 🐦🔥 works zero-shot (out-of-the-box) on unseen cohorts, patients, organs, and tissues — no fine-tuning needed. This is the start of a real shift in how we'll use pathology archives. Hypothesis generation at this scale opens up questions we couldn't realistically ask before, especially in understudied tissues and subtypes.
1/7🎉 Introducing Phoenix: generative AI predicting spatially resolved gene expression from routine H&E slides-enabling virtual spatial-omics. Zero-shot. Across cancers, organs & species.
Huge thanks to my co-first @TranManuel & all collaborators! 🙌
📜: doi.org/10.64898/2026.04.25.…

























