Professor of Genetics and Reproduction @biouea Founder and Scientific Director of Virilitas Labs Ltd https://xitter.cf/t.co/PjwMR9e6Hu
University of East Anglia, UK
Joined August 2014
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Are you interested in doing a PhD and are you interested in understanding how our changing climate affects the heritable genome? Come and join us @uniofeastanglia as an @NERCscience funded ARIES DTP student and apply here:
aries-dtp.ac.uk/studentships…
🤖 Made with AI
This is a simple parsimonious model to explain the evolution of lifespan extension by dietary restriction and other forms of stress that suppress fertility.
Happy to be part of this exciting study!
1/8
Why does eating less extend lifespan? 🧬
We often think about saving energy or recycling waste - but we show how evolution acting on mutation load can generate longer life on low food 🧵
and preprint below:
🔗 tinyurl.com/jn5ryhxv
Simone Immler retweeted
🚨Our new paper @SimoneImmler
FishPi: a #bioinformatic prediction tool to link #piRNA and #transposable elements
Read now in Mobile DNA >> rdcu.be/d7Jub ✅ Covers many species (more to come) ✅ GUI based software #TESky #zebrafish #transposons
@biouea
🐟🥧🥧🥧🥧🥟
Simone Immler retweeted
We had a great end to 2024 publishing:
The Zebrafish Sperm Proteome
analyticalsciencejournals.on…
We described >5400 sperm proteins generating a great atlas for future work!
Spearheaded by PhD student @JaymeCohenBIO with great collaborators at @biouea and @JohnInnesCentre
We had a great end to 2024 publishing:
The Zebrafish Sperm Proteome
analyticalsciencejournals.on…
We described >5400 sperm proteins generating a great atlas for future work!
Spearheaded by PhD student @JaymeCohenBIO with great collaborators at @biouea and @JohnInnesCentre
Simone Immler retweeted
🚨 Happy to share my latest preprint on #polarbear #transposon activity in response to diverging climates in #Greenland #TEsky 🐻❄🌞❄️🧬👩💻
Diverging transposon activity among polar bear sub-populations inhabiting different climate zones biorxiv.org/cgi/content/shor… #biorxiv_evobio
Simone Immler retweeted
🚨Pleased to share our latest preprint on #zebrafish #geneexpression and #transposons in #sperm & #embryos exposed to social stress
Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring biorxiv.org/cgi/content/shor… #biorxiv_evobio
I finally caved and am now on bluesky - help me finding you and follow me there @immler.bsky.social and send me starter packs!
Thank you!
Simone Immler retweeted
We have PhD position advertised in evolution of ageing with Tracey Chapman and @SimoneImmler:
Please contact me if you have questions about the project or about this PhD programme
aries-dtp.ac.uk/studentships…
Simone Immler retweeted
Why is there so much diversity in male seminal fluid proteins?
Funded PhD position available with Tracey Chapman @biouea
Research team includes @WolfnerLab , @WHaerty , @SimoneImmler and me
biodtp.norwichresearchpark.a…
Applications deadline Nov 25
Simone Immler retweeted
I am also incredibly proud of this preprint:
Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbiota-gut-brain axis....
biorxiv.org/content/10.1101/…
Again a massive team effort by @Ko0L_J_ @asdfjohnny @AliceGodden @JaymeCohenBIO et al!
Simone Immler retweeted
Incredibly excited to share our preprint (shorturl.at/JTwuJ) from
@SimoneImmler’s Lab 🥳!
By harnessing genomics, proteomics, and phenomics, we show that selecting high-quality sperm within an ejaculate could reduce the risk of diseases in future generations 🤯!
I am incredibly proud of this paper in preprint:
Within-ejaculate haploid selection reduces disease biomarkers in human sperm
lnkd.in/dZwDJHbX
It has been long in the making and has been a true team effort!
@danielmarcu @JaymeCohenBIO @AliceGodden @GAlavioon et al!
Simone Immler retweeted
I am incredibly proud of this paper in preprint:
Within-ejaculate haploid selection reduces disease biomarkers in human sperm
lnkd.in/dZwDJHbX
It has been long in the making and has been a true team effort!
@danielmarcu @JaymeCohenBIO @AliceGodden @GAlavioon et al!
I am also incredibly proud of this preprint:
Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbiota-gut-brain axis....
biorxiv.org/content/10.1101/…
Again a massive team effort by @Ko0L_J_ @asdfjohnny @AliceGodden @JaymeCohenBIO et al!
I am incredibly proud of this paper in preprint:
Within-ejaculate haploid selection reduces disease biomarkers in human sperm
lnkd.in/dZwDJHbX
It has been long in the making and has been a true team effort!
@danielmarcu @JaymeCohenBIO @AliceGodden @GAlavioon et al!
Simone Immler retweeted
Germline removal benefits males more than females - led by @martin_i_lind in @AgingCell : onlinelibrary.wiley.com/doi/… (see earlier bioRxiv link below). Stress resistance improved in both sexes. Remarkable congruence with killifish work pubmed.ncbi.nlm.nih.gov/3875… @ItamarHarel
How does germline removal affect lifespan in females and males? There are theoretical arguments to suggest that germline is more costly to maintain in males, @martin_i_lind and friends tested this in C. remanei 1/2:
biorxiv.org/content/10.1101/…
Simone Immler retweeted
Reduced insulin/IGF-1 signalling upregulates two anti-viral immune pathways, decreases viral load and increases survival under viral infection in C. elegans by @E_Duxbury et al
📢New Open🔓 Access Paper
Reduced insulin/IGF-1 signalling upregulates two anti-viral immune pathways, decreases viral load and increases survival under viral infection in C. elegans by Elizabeth M. L. Duxbury & @AlexeiMaklakov et al.
rdcu.be/dEfia
#insulinsignalling #antiviralimmunity #healthyaging #senescence #celegans
Simone Immler retweeted
I am very happy to announce the recent publication of a beautiful theory paper with @mscott0106 and Karl Mackintosh (not on X) on the interactions between mating system evolution and haploid gametic selection in @PLOSGenetics
doi.org/10.1371/journal.pgen…
Simone Immler retweeted
Merger of NYRA @YoungAndrology with @EAAndrology is highlighted in this society news article published in Andrology 🤩
onlinelibrary.wiley.com/shar…
@AndrologyASA
We are happy to share the story about NYRA/ @EAAndrology Merger:
onlinelibrary.wiley.com/doi/…
The Andro family is growing 🫱🏼🫲🏾✨