Welcome to StainsFile by @STEMCELLTech! Here, you can enjoy easy and open access to all the protocols and supporting resources you need to help you fix, prepare, and stain specimens: stainsfile.com 👩🏽‍🔬💻🧫🔬 #cellstaining #histology #microscopy #microscopymonday

💡 New review alert from Dr. Paul Harms at @UMich! This review details pitfalls and nuances for Merkel cell carcinoma (#MCC) diagnosis, including an updated differential diagnosis: bit.ly/4z5cQB8 #Immunohistochemistry

Researchers created a nearly complete human genome reference to help laboratories assess sequencing accuracy in disease-associated regions often excluded from validation tools. 🧬 Check out the nearly 1 billion new bases... 🗞️ bit.ly/4xWpx06 🧪 bit.ly/46VRpq3

Amino group 🤝 Carboxylic acid This is your sign to review your amino acids. From isoelectric point to accentuators, these basic building blocks play a huge role in staining. 🔖 Bookmark the guide so you're never caught mixing up glycine and alanine: bit.ly/4z6zlWh

How do we create more efficient, scalable #histopathological workflows? 🪜This paper uses AI-based segmentation of H&E sections to provide researchers with a new step up. See the deep-learning framework for detecting occult cervical lymph node metastases: bit.ly/4hTXUjj

New tech could help move polarization imaging into routine diagnostic workflows. The prototype offers a label-free method for analyzing cancerous tissue, helping to reduce reliance on #staining in #histopathology. Learn more: bit.ly/3TYt7c3

Got air-liquid interface or monolayer cultures in need of staining? Check out this protocol for whole-mount #immunocytochemical staining for almost any tissue type. In less than ten steps, you'll be ready for your session at the #confocal microscope! 🔬 bit.ly/3X4dQnR

Single-cell master regulator analysis of multiple #PDAC cohorts identified malignant cells in three co-existing, molecularly distinct developmental lineage states, each with distinct histopathological morphologies and spatial architecture. Abstract: go.nature.com/3VXXnUU

Pathology Visions is just over a week away in San Diego, CA! 🌴 Whether you are a seasoned clinician or a curious trainee, its not too late to join and learn about the future of digital pathology and AI. Learn more: bit.ly/4juTfp9

Has a new semester brought new labmates to the bench? 🥽 Send them this resource for safety sheets and best practices when dealing with #histotechnology chemicals and reagents. Safety is no accident! bit.ly/3TTufO9

Angiofibroma of soft tissue is a rare benign fibroblastic/myofibroblastic neoplasm. 🔍 This study identified a distinctive cytological features to support accurate diagnosis: vascular patterns within distinct stromal backgrounds. Learn more: bit.ly/4zvhp8K #Pathology

This guide from @iHisto summarizes staining by organ across brain, lung, liver, tumor, and more, covering #H&E, special stains, IHC, multiplex IF, and ISH. Check it out to help you design your next staining session or improve your current workflows: bit.ly/4cKWKDR

😵‍💫 Flummoxed by fixation? This protocol is optimized for whole-mount fixation of epithelial organoids for #immunostaining. It covers both dehydration and cross-linking methods for #ChemicalFixation, giving you more options with your samples: bit.ly/4y3xiBP

Dr. Roger Li (@UrogerliMD) at @MoffittNews and his colleagues have published a comprehensive review of the most common #BladderCancer subtypes. They discuss the histological subtypes and divergent differentiation of urothelial carcinoma. Read the abstract now: bit.ly/4geHSjm

🧠 The #BloodBrainBarrier poses unique challenges for #histotechnology. New research proposes an innovative histological workflow that enhances how researchers evaluate probe penetration and brain pathology. Learn more: bit.ly/4gQPrwJ

Can you name all the different ways to stain #ElasticFiber? 🔖 From orcein dye to iron resorcin fuchsin to aldehyde fuchsin to iron hematoxylin and more, bookmark this resource to broaden your staining toolkit and hone your technique: bit.ly/4ymJIFd #Histology