The lab of Dr. Nephi Stella studies the molecular mechanism and therapeutic value of cannabinoid-based molecules.
University of Washington
Joined July 2021
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Lab of Dr. Nephi Stella, University of Washington retweeted
Cannabidiol attenuates behavioral impairments and deficits in parvalbumin interneurons and their perineuronal nets induced by adolescent stress in adult mice
doi.org/10.1016/j.pnpbp.2026…
Lab of Dr. Nephi Stella, University of Washington retweeted
Acute Ultra Low Dose THC Attenuates Anxiety-Like Behavior in a Mouse Model for Major-Depressive Disorder
doi.org/10.1007/s12031-026-0…
Lab of Dr. Nephi Stella, University of Washington retweeted
So excited to finally share this collaborative work exploring the role of CADM2 recursive splice site deletions led by @Philip_M_Boone. We (@JKhokharLab) were fortunate to characterize the neural and behavioural consequences of CADM2 RS1 deletion cell.com/cell-reports/fullte…
Lab of Dr. Nephi Stella, University of Washington retweeted
This is, frankly, an amazing study. Given ongoing human trials this, I think, provides context,
Stepwise engagement of cingulate ensembles underlies motivational decline in chronic pain: Neuron cell.com/neuron/fulltext/S08…
Lab of Dr. Nephi Stella, University of Washington retweeted
Prediction: no one will care about journal names in 5 years.
Lab of Dr. Nephi Stella, University of Washington retweeted
Cannabinoid modulation of central amygdala population dynamics during threat investigation
nature.com/articles/s41467-0…
Lab of Dr. Nephi Stella, University of Washington retweeted
🐭 Low-THC, CBD-rich hemp oil boosted sociability in mice — no sedation, no side effects. An early lead for conditions like autism.
doi.org/10.1089/can.2021.001…
Lab of Dr. Nephi Stella, University of Washington retweeted
📢 New Study: Cannabis use patterns in cannabinoid hyperemesis syndrome (CHS) 🤢
🔹 Survey of 1,134 respondents
🔹 96.5% used cannabis at least daily; 45% used ≥6 times/day near symptom onset
🔹 Morning nausea & stomach pain were common early symptoms
⚠️ Self-reported observational survey; causality cannot be inferred
➡️ Patterns may support earlier CHS recognition
🔗 f.mtr.cool/tq74o4jj4r
#MedicalCannabis #CannabisResearch #CannabisEducation #CHS #HarmReduction
Lab of Dr. Nephi Stella, University of Washington retweeted
🚨 We're hiring!
The @PainLaboratory at @YalePsych is recruiting a #postdoc in #pain & #addiction neuropsychopharmacology.
Human lab studies of #cannabinoids & #psychedelics:
pharmacokinetics/pharmacodynamics, psychophysics, clinical trials. PhD/MD.
medicine.yale.edu/lab/pain/p…
Lab of Dr. Nephi Stella, University of Washington retweeted
@HutchBasicSci is searching for an associate or senior faculty member! Generous package thanks to donation from Bezos family:apply.interfolio.com/193655. Come join us in Basic Sciences
Lab of Dr. Nephi Stella, University of Washington retweeted
Someone finally ran the control experiment that drug discovery has been skipping for the last fifty years, and the result is going to to make your weekly med chem meetings kind of awkward :)
doi.org/10.1038/s41586-026-1…
Lab of Dr. Nephi Stella, University of Washington retweeted
Anandamide blocks spatial memory reconsolidation in male rats through a CB1 receptor dependent mechanism
doi.org/10.1007/s00213-026-0…
Lab of Dr. Nephi Stella, University of Washington retweeted
📢 New Study: THC and CBD affected rat brain activity differently 🧠
🔹 Preclinical multimodal neuroimaging
🔹 Adult male rats received THC, cannabidiol (CBD), THC:CBD, or vehicle
🔹 THC increased functional connectivity and cerebral blood flow; CBD decreased connectivity without changing blood flow
⚠️ Rat study; findings may not generalize to humans
🔗 f.mtr.cool/9aarwu0fcy
#MedicalCannabis #CannabisResearch #CannabisEducation #Neuroimaging #CBD
Lab of Dr. Nephi Stella, University of Washington retweeted
Great interview between @trikomes and @StellaLab11 about endocannabinoids. Talks a lot about enzymatic conversion and metabolism of anandamide and 2AG. For your listening pleasure:
youtube.com/watch?v=QqQU576h…
Honored to give a seminar at the prestigious Department of Pharmacology, University of Viginia, this Thursday September 10, 2026, at 9:30am in Pinn Hall 5023. I hope to see you there!
Lab of Dr. Nephi Stella, University of Washington retweeted
Medical Cannabis Reduces Pain, Insomnia Or Mood Issues In 91% Of Older Adults, Study Finds: "Older adults receiving supervised medical cannabis experienced favorable symptom evolution during follow-up."
marijuanamoment.net/medical-…
Lab of Dr. Nephi Stella, University of Washington retweeted
A transient mitochondrial switch underlies long lasting effects of adolescent cannabis
nature.com/articles/s41386-0…
Excited to share our study published today in Nature! This work by the CB Network at the University of Washington was led by Dr. David Marcus, myself and Dr. Micheal Bruchas. Considering how challenging it is to publish in such a high impact journal, I am full-on celebrating.
Fig. 4 | aPVT–Nac Penk neurons facilitate engagement in reward seeking in an eCB-dependent manner using our BioSyft's BehaviumTM machine-learning pose-estimation technology🥇.
Considering how challenging it is to publish in such a high impact journal, I am genuinely celebrating this accomplishment.
nature.com/articles/s41586-0…
