@TangramTx
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Relentless medicine discovery.
London, England
Joined May 2015
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History made again! Huge congratulations to Bodhana who has become the youngest ever female international master♟️
11-year-old Bodhana Sivanandan continues to make history, this time by breaking Judit Polgar's record as the youngest ever female IM — and the 7th youngest ever! chess.com/news/view/bodhana-…
We're pleased to announce the appointment of Dr Laura Roca-Alonso as CEO and Board Director. Since 2020, Laura has been fundamental in advancing our pipeline, platform and strategy, first as Chief Operating and Business Officer and then as Interim CEO over the past six months.
Find out more: tangramtx.com/press-release/…
A hugely impressive achievement from Tangram-sponsored Bodhana Sivanandan, who has become the youngest ever Woman Grandmaster at just 11 years old. Congratulations from everyone at Tangram, Bodhana!
bbc.co.uk/news/articles/cqwy…
Today we announced a CEO transition at Tangram. Laura Roca-Alonso, who has served as COO/CBO since 2020, has been appointed Interim CEO, following Ali Mortazavi's decision to step down.
Laura has played a central role in building Tangram over the past six years, and we’re excited for her to lead the team as we continue to advance our GalOmic pipeline and deliver key upcoming milestones.
Find out more at link below đź”—
One step closer to bringing new medicines to patients.
The first participant has been dosed in our Phase 1/2 RESTORE-MASH trial evaluating GalOmic RNAi medicine, TGM-312, in healthy volunteers and people living with MASH.
Link below đź”—
We’ve announced our first CTA submission, advancing TGM-312 for MASH into the clinic. Discovered in-house and backed by robust preclinical data, TGM-312 shows potential as a truly differentiated treatment option for people living with MASH. Find out more: tangramtx.com/press-release/…
Our GalOmic siRNA, TGM-312 for the treatment of MASH, has shown outstanding data in Gubra’s highly translatable GAN DIO-MASH model and is now advancing toward a CTA submission in Q4 2025.
If you're at #TIDESEurope, attend our presentation to find out more.
e-therapeutics has relaunched as Tangram Therapeutics and simultaneously unveiled our next-generation AI platform LLibra OS. We're poised to unlock the true promise of RNAi medicines as we progress towards the clinic by the end of 2025.
We've announced significant progress on ETX-312, our lead GalOmic therapy for MASH:
âś… Positive non-clinical data with ETX-312 well tolerated across all dose levels
âś… On track for CTA submission in Q4 2025
Find out more here: etherapeutics.co.uk/news-and…
On Friday we presented our preclinical data on ETX-148 in haemophilia at @EAHADnews! It was a great opportunity to learn more about the latest advancements in the space and share our own data with the bleeding disorders community.
Final SLAM speakers Sidonio Jr, Frenzel, and Pursell report back on the use of prothrombin complex concentrate with non-factor therapies, dose escalation outcomes in novel treatment trials, and preclinical safety & efficacy data for emerging therapies in #haemophilia A&B
We are progressing towards the clinic! 🚀 Find out about our latest progress towards becoming a clinical-stage company and continued development of our HepNet platform in our business update and interim results, published today: etherapeutics.co.uk/news-and… #RNAi #AI #Biotech
We are looking forward to presenting new data from our GalOmic therapeutic pipeline at upcoming scientific conferences! Find out more here: etherapeutics.co.uk/news-and… #RNAi #siRNA #MASH #Cardiometabolic #Biotech #AI
Today, #ETX-sponsored Bodhana met with @RachelReevesMP at Downing Street as she prepares to represent England in the upcoming Chess Olympiad at just 9 years old. Good luck from everyone at ETX! #chess #biotech
We are extremely proud of #ETX-sponsored chess prodigy Bodhana who, at just 9 years old, will be the youngest person to represent England in an international sporting competition when she plays in the Chess Olympiad in September! theguardian.com/sport/articl… #biotech #chess #AI
