Teheimar

Systems surprise us when things below the surface burst through: they 'flip' into a new state. As more people accept that SARS-2 is harmful, as the wish for protections grows, the pressure to break the social norm of no protections will shatter, and a new norm will emerge.

🇷🇺 PUTIN'S REGIME COULD COLLAPSE. BUT WHAT COMES AFTER IT MIGHT BE EVEN MORE DANGEROUS. British historian Antony Beevor has raised a disturbing possibility about Russia's political future: the fall of Vladimir Putin might not bring democracy, and the consequences of a violent collapse could be catastrophic. His concern is rooted in Russia's own revolutionary history. Beevor invokes the 19th-century Russian thinker Alexander Herzen and his metaphor of the "pregnant widow", a society in which the old political order has died but the system that will replace it has not yet been born. Such moments can create extraordinary opportunities for political change. But they also leave societies dangerously vulnerable to those willing to seize power. Russia has experienced this before. Following the collapse of the tsarist monarchy in February 1917, the country briefly appeared to have an opportunity to establish a more representative political system. That possibility was ultimately destroyed by the Bolsheviks. Beevor points to the fate of Russia's Constituent Assembly, which was dissolved after Lenin and his supporters refused to accept a political institution that threatened their monopoly on power. For Beevor, the lesson is that overthrowing an autocracy does not automatically create a democracy. A new authoritarian movement can exploit the resulting instability and eliminate the institutions that might otherwise constrain it. But he is skeptical that Putin's Russia is approaching such a revolutionary moment. According to Beevor, the Russian state possesses 27 different security organizations, creating an extensive apparatus of surveillance, coercion and institutional control. He considers the system so rigid that he sees little prospect of either a popular uprising or even a successful palace revolution. When Russian Communist leader Gennady Zyuganov suggests that another February 1917 could be approaching, Beevor dismisses the idea. His greatest fear, however, concerns what could happen if the regime collapsed despite those obstacles. A struggle between competing political, military and security factions could potentially descend into civil war. And in a country as large, heavily armed and politically fragmented as Russia, Beevor warns that such a conflict could become an extraordinarily dangerous crisis, one that outside powers would have very limited ability to control. The implications extend far beyond Russia's borders. Russia possesses a vast nuclear arsenal, extensive military infrastructure and numerous security institutions whose loyalties could become uncertain during a severe breakdown of central authority. A sudden collapse would therefore raise questions not only about who governs Russia, but also about who controls its weapons and coercive institutions. Beevor's argument is not that Putin's continued rule is desirable. It is that removing an authoritarian ruler and establishing a stable democratic system are two entirely different challenges. Russia's history offers examples of political collapse producing new forms of repression rather than lasting freedom. And that is the uncomfortable possibility Beevor wants people to consider. The end of Putin's regime could mark a historic turning point. Whether that turning point leads toward democracy, another dictatorship or a violent struggle for power would depend on what follows, not simply on the departure of the man currently ruling the Kremlin.

1983 Ford Lincoln Continental Concept 100, had a moving map screen with the car’s location on it. It pulled position fixes from old Navy Transit satellites every hour and a half or so (accurate to about a quarter mile). Between fixes it just used a compass and sensors on the wheels to keep track (known as dead reckoning). Map lived in the car’s memory with an 80K of EPROM chip with 16K of RAM, drawing the map and controls in custom software. One of the first real attempts at putting a moving map and satellite location in a car.

Official ranking of US cities for single men: 1) NYC — Greatest dating market on earth. Unlimited women, 5 Hinge dates a week, and a new girl at every bar. Even the 5'8 fat accountant has options… 2) Miami — Beautiful women everywhere. Beaches, boats, nightlife. If you're jacked, tan, and have a little money, you're living like a king. If not, just make money. 3) Chicago — NYC on easy mode. Hot Midwest girls, great bars, affordable dates. Women actually want relationships. 4) Austin — Liberal California girls dating conservative Texas bros (well maybe not anymore...) Tech money, rooftop bars, and a new Pilates instructor moving in every week. 5) Nashville — Sorority girl retirement home. Broadway is a nonstop bachelorette party. You can meet 15 women before midnight. 6) Dallas — Blonde SMU girls, country clubs, and $30K millionaires. Every girl wants a 6'2 guy with a truck, a Rolex, and a ring by 28. 7) Charleston — Best wife market in America. Southern belles, beach weekends, and girls who actually want marriage before 30. 8) Atlanta — Beautiful women, insane nightlife, and more attractive people at brunch than most cities have at night. Competition is brutal. Lots of fat people too tho. 9) Boston — Educated women, great jobs, and plenty of single nurses. Unfortunately every first date turns into a job interview. 10) San Diego — Gorgeous women, beaches, perfect weather. Every girl does Pilates and has an ex who surfs professionally. Issue here is… competition is tough and lots of dudes. 11) Los Angeles — Models and influencers everywhere. Unfortunately everyone is dating 6 people and waiting for someone famous to DM them. 12) Denver — Fit outdoorsy women everywhere. If you don't ski, hike, or own a golden retriever, you're invisible. It’s called Menver for a reason tho. 13) Seattle — Tech bros making $300K competing for the same 4 women on Hinge. Better off moving. 14) San Francisco — $250K salary, 800 credit score, zero matches. Your competition is an AI founder who hasn't touched a woman since 2019.

Official ranking of US cities for single men: 1) NYC — Greatest dating market on earth. Unlimited women, 5 Hinge dates a week, and a new girl at every bar. Even the 5'8 fat accountant has options… 2) Miami — Beautiful women everywhere. Beaches, boats, nightlife. If you're jacked, tan, and have a little money, you're living like a king. If not, just make money. 3) Chicago — NYC on easy mode. Hot Midwest girls, great bars, affordable dates. Women actually want relationships. 4) Austin — Liberal California girls dating conservative Texas bros (well maybe not anymore...) Tech money, rooftop bars, and a new Pilates instructor moving in every week. 5) Nashville — Sorority girl retirement home. Broadway is a nonstop bachelorette party. You can meet 15 women before midnight. 6) Dallas — Blonde SMU girls, country clubs, and $30K millionaires. Every girl wants a 6'2 guy with a truck, a Rolex, and a ring by 28. 7) Charleston — Best wife market in America. Southern belles, beach weekends, and girls who actually want marriage before 30. 8) Atlanta — Beautiful women, insane nightlife, and more attractive people at brunch than most cities have at night. Competition is brutal. Lots of fat people too tho. 9) Boston — Educated women, great jobs, and plenty of single nurses. Unfortunately every first date turns into a job interview. 10) San Diego — Gorgeous women, beaches, perfect weather. Every girl does Pilates and has an ex who surfs professionally. Issue here is… competition is tough and lots of dudes. 11) Los Angeles — Models and influencers everywhere. Unfortunately everyone is dating 6 people and waiting for someone famous to DM them. 12) Denver — Fit outdoorsy women everywhere. If you don't ski, hike, or own a golden retriever, you're invisible. It’s called Menver for a reason tho. 13) Seattle — Tech bros making $300K competing for the same 4 women on Hinge. Better off moving. 14) San Francisco — $250K salary, 800 credit score, zero matches. Your competition is an AI founder who hasn't touched a woman since 2019.

Former CIA Director David Petraeus: With Budanov now heading the Presidential Office, Zelenskyy has someone close to him who deeply understands the military situation and ongoing operations. I know Budanov well. He is very direct in his assessments. We first spoke by video when he was near the russian border, commanding one of the first operations on russian territory. Petraeus in an interview with SpyCast: Ukraine has the largest and most innovative army in Europe. It is doing what NATO armies would otherwise have to do themselves if russia achieved its objectives in Ukraine. Moldova would be next, and possibly Lithuania after that. During my recent visit to Ukraine, a russian jet-powered drone struck the locomotive of a train on the track next to ours. The passengers on trains leaving Ukraine are mostly women and children. It was terrifying for them. Russia has suffered 1.5 million killed and wounded, more than the United States suffered during the entire Second World War. Last month alone, Ukraine estimated approximately 46,000 russian casualties, while russia recruited only around 30,000 soldiers. New recruits receive very little training. Ukrainian forces have captured russian soldiers who had been in the army for less than two weeks. They are practically cannon fodder. Ukraine has struck every russian oil refinery within 3,000 kilometers of its border, many of them multiple times. Russian oil production has fallen below 9 million barrels per day for the first time since 2009. Russians now use smartphone apps to find gas stations that still have fuel. The National Welfare Fund has been redirected toward the military-industrial complex and is expected to run out by the end of the year. It is time for Europe and the United States to seize frozen russian reserves and provide them to Ukraine. We tend to assume that Ukrainians are far ahead in military innovation, just as we assume the United States leads in artificial intelligence. But when you look closely, the gap is not always that large. In some areas, the russians have developed capabilities before the Ukrainians. China, North Korea, and Iran are carefully studying what is happening in Ukraine. The West needs to learn from Ukraine much faster. Simply buying drones for existing tank units is not enough. We need to fundamentally rethink our military structures because many traditional Western weapons systems would no longer survive on the Ukrainian battlefield. And we need to do this immediately. The Ukrainian people have demonstrated extraordinary resilience. They have been absolutely unbreakable despite enormous pressure. But they are also exhausted, and another difficult winter lies ahead. Source: SpyCast

While you sleep, your brain's white matter is charging up like a battery Myelin, the insulation around your nerve fibers, has been considered a passive structural component that speeds up signals. A new hypothesis from @FScholkmann and colleagues proposes it's actually an energy storage system that fills up during sleep and powers your neurons throughout the day. The paper, published in Progress in Biophysics and Molecular Biology, presents a radical reimagining of what myelin does beyond speeding up electrical signals along nerves. What is myelin? Myelin is the fatty sheath that wraps around nerve fibers like insulation around electrical wires. It's produced by specialized cells called oligodendrocytes in the central nervous system and makes up about 40% of your brain's volume. Traditionally, myelin's job has been simple: speed up nerve signals and provide structural support. This new hypothesis suggests it does something far more dynamic. The proton capacitor hypothesis The researchers propose myelin functions as a proton capacitor, meaning it stores energy in the form of protons (hydrogen ions) that accumulate during sleep and get released during wakefulness to produce ATP, the cell's energy currency. Think of it like a rechargeable battery. During sleep, myelin charges up by accumulating protons. During wakefulness, those protons flow through ATP synthase enzymes embedded in myelin, generating the energy neurons need to function. The mechanism involves two abundant myelin proteins: Myelin basic protein (MBP) sits between myelin layers and contains amino acids (lysine, arginine, histidine) that can absorb and hold protons. It functions as the energy storage component. Proteolipid protein (PLP) spans the myelin membrane and contains serine and threonine amino acids that form efficient proton conductors, creating pathways for protons to flow from storage sites to ATP synthase. How the charging cycle works During sleep, your myelin is actively storing energy. Specialized molecules in myelin pump protons (think of them as tiny charged particles) into storage proteins, like filling up a battery. During this phase, no energy is being used, just stored. When you wake up, the system switches into discharge mode. Those stored protons flow through protein channels to enzymes that convert them into ATP, your cells' usable energy form. This ATP travels through tiny tunnels called gap junctions directly into nerve fibers, where it powers your brain's activity. The researchers calculated that the amount of protons a small cube of myelin can hold matches exactly what your brain would need during 8 hours of wakefulness. The storage capacity and the daily demand align. The molecular sleep switch A naturally occurring molecule called oleamide acts as the on/off switch for this system. Throughout your waking hours, oleamide gradually accumulates in your brain. When it reaches a certain level, it closes those gap junctions, the tunnels that deliver ATP from myelin to nerve fibers. Once the tunnels close, your neurons can't access the energy supply. Neural activity drops. You get sleepy. With the delivery system shut down, myelin switches from discharge mode to charging mode. While you sleep, oleamide slowly breaks down. When enough of it clears out, the gap junctions reopen, ATP starts flowing to neurons again, and you wake up. This explains why you can't just decide to stay awake indefinitely. As oleamide builds up during the day, it eventually forces the system offline whether you want it to or not. Sleep isn't optional, it's a programmed metabolic requirement driven by molecular accumulation. How myelin produces energy without the usual machinery Here's where it gets strange: myelin can make ATP (cellular energy) even though it doesn't contain the typical power plants that cells use to generate energy. Normally, structures called mitochondria produce nearly all of a cell's ATP. But myelin has very few, if any, complete mitochondria. So how does it make energy? The researchers propose that mitochondria send small cargo packages carrying energy-producing equipment to the myelin. These packages fuse with myelin membranes and drop off the machinery, allowing myelin to produce ATP on its own. Think of it like getting a portable generator delivered to a remote cabin. You don't need a full power plant on site, just the essential equipment to generate electricity locally. The bigger the battery, the less time spent charging The researchers examined 23 different mammal species and discovered something remarkable: animals with more white matter (the brain tissue that's 95% myelin) need less sleep. Here's the pattern: • Bats have tiny brains with minimal white matter and sleep 20 hours a day • Humans have moderate white matter and sleep 8 hours a day • Elephants have massive white matter and sleep just 3.5 hours a day The logic is straightforward. More myelin means greater energy storage capacity. With a bigger battery, you need less time plugged in to fully recharge. The pattern suggests that more myelin provides greater energy storage capacity, reducing the time needed to recharge. Less myelin means longer recharging periods are required. This relationship also appears within humans across the lifespan. White matter volume peaks between ages 30-50, the same period when sleep duration reaches its minimum. Both follow inverted U-shaped curves over the human lifespan. Even sex differences align: women have less white matter than men and require more sleep on average. Experimental support The hypothesis draws on experimental work showing: • Isolated myelin vesicles consume oxygen and synthesize ATP via oxidative phosphorylation • Myelin vesicles exposed to NADH retain an energy charge that's later used for ATP synthesis when ADP and phosphate are added • Longer exposure to NADH produces more ATP in subsequent phases • This matches the predicted two-phase system: charging during simulated sleep, discharge during simulated wakefulness Sleep deprivation studies show myelin thickness decreases when animals are kept awake, consistent with discharge without adequate recharging time. Marathon runners show notable reductions in myelin after intense physical activity, suggesting the energy reserves get depleted during sustained neural and physical exertion. Key takeaways: • Myelin may function as a proton battery, storing energy during sleep and releasing it during wakefulness • Two myelin proteins (MBP and PLP) form a coupled system: one stores protons, the other conducts them to ATP synthase • Sleep duration correlates with white matter volume across 23 mammalian species • Oleamide, a natural sleep inducer, closes the gap junctions that deliver ATP from myelin to axons • Myelin contains functional mitochondrial components delivered via mitochondrial-derived vesicles • The human brain requires approximately 8 hours to fully recharge myelin's proton storage capacity • Sleep deprivation leads to measurable myelin degradation Limitations and open questions This remains a hypothesis requiring direct experimental validation in living systems. The calculations provide plausibility but don't prove the mechanism operates as proposed. Key questions: • Can proton accumulation and discharge be measured directly in myelin during sleep/wake cycles? • Does blocking this proposed system prevent normal sleep function? • How does this mechanism integrate with other established functions of sleep? • Can therapeutic interventions targeting this system improve sleep quality or neurological function? The challenge is that protons moving between membrane-bound buffers without entering free solution is difficult to measure experimentally. Why this matters If validated, this hypothesis fundamentally reframes our understanding of sleep. Rather than viewing sleep as a period when the brain passively recovers, it positions sleep as an active metabolic phase when the brain's white matter systematically stores energy for the next waking period. It also elevates myelin from a passive structural element to an active metabolic organizer that administers energy distribution to neurons. The framework could explain why myelin disorders often involve fatigue and why conditions affecting white matter integrity produce cognitive deficits even when gray matter remains intact. The identification of oleamide as the molecular switch controlling this cycle points to a natural compound that's been overlooked as a potential sleep therapeutic despite decades of evidence. The convergence of structural data (protein composition and positioning), metabolic data (oxygen consumption and ATP synthesis in myelin), molecular data (oleamide and gap junctions), and cross-species data (white matter volume and sleep duration) creates a compelling case that myelin plays a previously unrecognized role in sleep energetics. Whether this represents the primary function of sleep or one component of a multi-system process remains to be determined. But the hypothesis provides testable predictions and a mechanistic framework for understanding the metabolic foundations of the sleep-wake cycle.

No one who judges you for wearing a respirator will be there for you if you find yourself chronically ill or Disabled. #MaskUp

🖖Oldest living member of the original Star Trek cast. Want to live long and prosper? Consider wearing an N95 respirator 👇

Can you imagine if kids who are getting multiple Covid infections now seem okay but then start developing serious issues 40 years later, like kids with polio did? That's if they manage to get past their 1-2 infections a year for the next 40 years. Does no one stop to think?

I’ve talked to enough guys to understand the #1 insecurity in the male species is height… Accept these 3 things: 1. Women will never stop selecting based on height They want to feel small, protected, and taken care of. Height signals all of this at a primordial level. It’s a basic evolutionary adaptation based on increased chance of procreation. You don’t get shaken up about having sweat glands do you? Because that’s just another adaptation that ensured we survived as a species. 2. Being distraught over something that you can’t change is insanity Anxiety exists to force an action that removes a threat. Height is 80% genetic and growth plates fuse at 18 years old. Caring about what people think of you will elevate cortisol chronically, leading to lower testosterone, a higher pitched voice, and weak posture… That’s why small guys look weak… It’s not height; It’s their reaction to their height. 3. You guys are tying up way too much of your lives in the casual dating market I’m 6’5 and good looking, of course that helps in the dating market… But the main benefit is casual relationships, it’s actually harder to maintain long term relationships because: - You have way more options (makes selective behaviour harder) - Every girl considers you a possibility to sleep with regardless of what’s right/wrong - You have no friends that are girls because there’s always some underlying desire All the looksmaxxing/height boosting behaviour only works for short term results; i.e. a casual hook up Real, quality relationships require sound minds, good values, and lack of trauma, and actually having your life set up (career, stability, health)… All in all: If something can’t change, thinking about is a disease that never ends… Be unabashedly you; That’s how you win.

❌ Calzado que un hombre >30 JAMÁS debería llevar: 🔴 INMADURO · Vans → Estilo instituto · Crocs con pines → Cero elegancia · Jordan → Desubicado 🟠 ESTANCADO · Náuticos → Envejecen 10 años · Running → Vagancia pura · Mocasín sin calcetín → Pasado de moda 🟢 TOP ↓↓