Transplant biologist and immunologist | Assistant Prof @MGHSurgery @mgh_transplant @HarvardMed. Tweets are my own
Boston
Joined November 2021
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🐷➡️🧬 In the first pig-to-human kidney transplant, a multiomics approach demonstrated that persistent innate immune activation (monocytes/macrophages) remains a key barrier. Better control of innate immunity will be critical for future success.
High-dimensional immune profiling of a living recipient of a pig-to-human #xenotransplant provides insight into the immune landscape of #xenotransplantation and directions for improved #immunosuppression strategies.
nature.com/articles/s41591-0…
Thiago J Borges, PhD retweeted
271 days. A record-setting step forward in xenotransplantation.
Tim Andrews spent 271 days with a genetically modified pig kidney, the longest time a pig kidney has functioned in a person. This milestone was made possible by the Mass General Brigham transplant teams’ work in xenotransplantation.
This breakthrough offers continued hope for the thousands of people waiting for a kidney transplant. Learn more about this groundbreaking milestone and the future of xenotransplantation. spklr.io/6016ErSa6
Check out our work at @ATCMeeting 2026!
Excited for #ATC2026!
Our team will contribute to 16 presentations covering transplant tolerance, recurrent glomerular disease, frailty, immune metabolism, immune regulation, and xenotransplantation,including the ATC plenary. Hope to see you there! @mgh_transplant @ThiagoJBorges
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Thiago J Borges, PhD retweeted
Incredible opportunity to lead our Living Donor Kidney Transplant Program @mgh_transplant
Join a collaborative, high-volume team (>240 tx/year) with real momentum in innovation and program growth (tolerance/xeno)
Know someone great or interested yourself:
jobs.myast.org/job/kidney-tr…
Looking forward to speak at the @AST_COTS Guest Symposium at the #IMMUNOLOGY2026™ @ImmunologyAAI with @ValeriaMas11
COTS Guest Symposium at IMMUNOLOGY2026™ in Boston April 17, 2026 8:00–9:30 AM : The Immunology of Xenotransplantation
Moderators: Dr. Anita Chong, Dr. Thiago J. Borges
Speakers: Drs. David K. C. Cooper, Valeria Mas, Thiago J. Borges, Brendan Keating
immunology2026.aai.org/regis…
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Thiago J Borges, PhD retweeted
We’re very excited to be hosting the first Glomerular Disease Conference in Boston on May 30th!
Join us to learn what’s new in glomerular diseases from world-class experts.
In-person and virtual options available.
Fellows/trainees can attend for free. DM for details.
Join us on May 30th for GLOMBoston 2026!
🔬This 1-day, live conference focuses on the understanding & management of glomerular disease
💬Learn from expert lectures & interactive case discussions
REGISTER TODAY: cpd.partners.org/content/mgb…
@BetterCallSeeth
@AlJurdi
@MGBKidneys
Check out our latest paper @amjtransplant 👇🏼👇🏼
🚨 Editor’s Choice 🚨
"Best practices in mouse models of skin transplantation," by Borges et al
amjtransplant.org/article/S1…
#SkinTransplantation #TransplantResearch #MouseModels
ALT Visual element to accompany article
Thiago J Borges, PhD retweeted
Historic moment in transplant medicine. Tim, our @mgh_transplant xenotransplant patient, who previously received a gene-edited pig kidney and was off dialysis for 9 months, has now received a human kidney. A new chapter in care and hope. cnn.com/2026/01/16/health/pi…
I’m very proud to have been the first Editorial Fellow on the Basic Science track @amjtransplant
This experience has been incredibly valuable for my development as a scientist. I strongly recommend this program to anyone interested in academic publishing.
American Journal of Transplantation is now accepting applications for the AJT Editorial Fellowship Program!
Work alongside journal editors. Build peer review and communication skills.
Applications open through Jan 31
amjtransplant.org/ajt-editor…
ALT AJT Editorial Fellowship
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A brief T–cell–mediated rejection occurred early, likely due to residual lymph node immunity, but was successfully treated. No antibody-mediated rejection was seen. @LVRiella @MassGeneralNews
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Thiago J Borges, PhD retweeted
Hot off the press @NatureMedicine: We report the first high-dimensional immune profiling of a living human recipient of a gene-edited pig kidney at @MGH_Transplant / @MGBKidneys, defining the evolving human xeno-immune response over time. nature.com/articles/s41591-0…
Thiago J Borges, PhD retweeted
In honor of Richard Slayman, the first pig kidney recipient, we hosted a workshop gathering global experts in xenotransplantation to explore unpublished clinical and ethical advances in kidney, heart, and liver transplantation.
#Xenotransplantation #TransplantInnovation
Thiago J Borges, PhD retweeted
Scientists have found that C/EBP⍺ activates an IRF8 #enhancer, driving its expression in early myeloid progenitors and specifying type I conventional #DendriticCell lineage. @washu_pathology @JingNeticist
Read more in Science #Immunology: scim.ag/3EUH8jF
Thiago J Borges, PhD retweeted
He’s thriving nearly 4 months after receiving a gene-edited pig kidney at @mgh_transplant @MGHSurgery @MGHKidneys @harvardmed. “He was tired of just surviving. A pig kidney gave him a shot at living.” @CNN
🔗 cnn.com/2025/05/14/health/xe…
🚨 Our new study in @SciTranslMed identified the inhibitory receptor Siglec-E as a critical brake on dendritic cell activation and T cell–mediated transplant rejection. 1/5
science.org/doi/10.1126/scit…
💡 Takeaway: Innate immune checkpoints like Siglec-E/7/9 are emerging as crucial regulators of transplant rejection. 4/5
📄 Newsroom @MGBResearchNews: massgeneralbrigham.org/en/ab…
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🚨 Great Opportunity! 🚨
The @LVRiella lab, @mgh_transplant, is seeking a Postdoc in Transplant Immunology with expertise in Microsurgery.
📍 Apply now! #Postdoc #Microsurgery #TransplantResearch
