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1/4 🚨 We’re hiring!
The Laboratory of AI & Systems Immunology (AISI Lab) at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine is recruiting:
• Assistant Researchers
• Postdocs
• Research Assistants
#Hiring #Immunology #CancerResearch #AI
Tiangen CHANG retweeted
🚨 Out today in Cell! @CellCellPress
Path2Space: #AI that predicts spatial transcriptomics (ST) from H&E pathology, enabling spatial biomarker discovery in #BreastCancer at scale.
📄 doi.org/10.1016/j.cell.2026.…
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Tiangen CHANG retweeted
🚨 Our pre-proof is out on @Annals_Oncology!
BRIDGE, a framework to quantify intratumoral subtype mixtures in #BreastCancer and predict neoadjuvant response, including directly from H&E slides
Paper: doi.org/10.1016/j.annonc.202…
🧵1/11
Tiangen CHANG retweeted
wow as of may 2025, there are 513 cancer vaccines in development, with 33 in phase 3 @NatRevDrugDisc
Tiangen CHANG retweeted
We've known how important the tumor microenvironment is for cancer progression and treatment, but we never had a non-invasive blood test to assess it. Today, as reported @nature, one has been discovered nature.com/articles/s41586-0…
Tiangen CHANG retweeted
Big Update🤩: #paperclip now includes full papers from all of arXiv, PubMed Central and 150 million abstracts!🖇️
You can give your LLM all that knowledge in one line—all optimally indexed for AI agents. Much more thorough and ~100x faster than web search, and free.
Tiangen CHANG retweeted
🚀Excited to share our new paper @Nature! We developed PerturbFate platform to discover how diverse genetic perturbations converge on a shared cell state, and key molecular programs driving it, led by our incredible student @xu_zxu from @RockefellerUniv.
rdcu.be/fdC14
Tiangen CHANG retweeted
Unprecedented overall survival benefit from Phase 3 RASolute 302 in previously treated metastatic pancreatic cancer.
Read the press release: ir.revmed.com/news-releases/…
#Oncology #PancreaticCancer
International lab website (English, regularly updated with research, lab news, datasets, etc):
– rootchang.github.io/AISI_Lab…
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3/4 If you're excited about tackling hard problems at the biology × AI × systems science frontier, we'd love to hear from you.
To apply:
Please send your CV + cover letter + contact info. of 2 refs to: [email protected]
Subject: “Application – [Position] – [Your Name]”
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4/4 All application materials will be kept confidential. Positions are open until filled.
For more info. visit
Lab page:
shsmu.edu.cn/sii/info/1164/4… (English) shsmu.edu.cn/sii/info/1053/4… (中文)
Research overview: doi.org/10.13140/RG.2.2.3150…
#ComputationalBiology #Postdoc #SystemsBiology
Tiangen CHANG retweeted
Wanted to share my rather tumultuous journey that has led to AI in cancer! Scientific careers are so often shaped by a multitude of false starts and redirections. Let your passion, resilience, and collaborations fuel you to meet the challenges of today!
rdcu.be/e6MFE
Tiangen CHANG retweeted
Can we predict response to #cancer treatment from #tumor transcriptomes instead of the standard-of-care DNA panels in #PrecisionOncology? Check out our large-scale evaluation across several commonly used cancer therapies! 👇
biorxiv.org/content/10.1101/… @rlipika @nishanth_UN
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Excited to share our new paper in @SciImmunology: "Hypoxia-induced EGR1 remodels neutrophils to suppress antitumor immunity." We identify EGR1 as a master regulator transforming neutrophils into potent suppressors of antitumor immunity. science.org/doi/10.1126/scii… #CancerImmunology.
11/12 Nancy P. Judd, Wojciech K. Mydlarz, Vassiliki Saloura, Alejandro A Schäffer, @EytanRuppin, Clint T. Allen), patients, and clinical teams who made this work possible. This was a true team effort combining immunology, genomics, spatial biology, and translational insight.
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12/12 Check out the full paper for more insights! We’d love to hear your thoughts—comments, questions, and collaboration ideas are all very welcome. science.org/doi/10.1126/scii…
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