Multidisciplinary research centre striving to understand how biological rhythms are regulated and define their importance for health.
Manchester, England
Joined November 2017
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How pond algae led to a Nobel prize and a new way to study the brain theconversation.com/how-pond… via @ConversationUK
Caloric restriction modulates genome-wide somatic mutation in mice sciencedirect.com/science/ar…
New paper from Eder Zavala's team at the CfBT
Regulation of ultradian pulsatility and stress responses in the human hypothalamic–pituitary–adrenal axis
onlinelibrary.wiley.com/doi/…
A new study from CfBT's Future Leaders Fellow Eder Zavala, published today in Science Translational Medicine!
science.org/doi/10.1126/scit…
#PrimaryAldosteronism #Hypertension #Endocrinology #CircadianRhythms #DigitalHealth #WearableTechnology #MathematicalBiomedicine
Biological Time MCR retweeted
Exercise may reshape our microbiome and immune system in ways that influence disease risk.
This timely review explores how exercise-responsive gut microbes and their metabolites, including short-chain fatty acids, secondary bile acids, and formate, may influence systemic inflammation, antitumor CD8 T-cell immunity, autoimmunity, and metabolic disease.
The exciting challenge now is to move from association to mechanism: Which microbes matter? What metabolites do they produce? And how does the host sense and respond to them?
#Exercise #Microbiome #Immunity #Metabolism #GutHealth #CancerImmunology #PrecisionMedicine
@TrendsImmuno @WuTsaiAlliance
sciencedirect.com/science/ar…
Biological Time MCR retweeted
Diversifying our activities!
theconversation.com/what-hap…
Biological Time MCR retweeted
Your body clock doesn’t just regulate sleep—it also shapes cancer biology. ⏰ Circadian rhythms influence DNA repair, metabolism, immunity, and treatment response, making chronotherapy a promising strategy to improve cancer outcomes while reducing toxicity. #CircadianRhythm #CancerResearch #Chronotherapy
jci.org/articles/view/198780…
Biological Time MCR retweeted
The club cell circadian clock regulates temporal patterns in leukocyte trafficking in chronic allergic airways disease from: @JafarCain @h_durrington @DrAmlanC @Time_MCR mucosalimmunology.org/articl…
Jafar Cain's PhD work published!
The club cell circadian clock regulates temporal patterns in leukocyte... sciencedirect.com/science/ar…
Biological Time MCR retweeted
A biology journal trialled paying their reviewers and found it led to faster first editorial decisions – and increased review quality.
go.nature.com/4v7XkSv
New invited review published by our Centre in The Journal of Biochemistry!
Nutrigenomic Regulation of One-Carbon Metabolism and the Circadian Clock in Health and Disease academic.oup.com/jb/article/…
Prof Hannah Durrington contributed to an article in The New York Times (account required to read)!
nytimes.com/2026/06/04/clima…
Biological Time MCR retweeted
Our new preprint is out! Congrats to 3rd year PhD student Jess!
A high-resolution, sex-stratified atlas of transcriptional and alternative splicing dynamics in the fasting mouse liver
biorxiv.org/content/10.64898…
New paper from our Centre!
The impact of self-selected light on activity rhythms in the diurnal striped mouse: Current Biology cell.com/current-biology/ful…
Biological Time MCR retweeted
journals.sagepub.com/doi/ful…. If you want to find out more about how chronotype influences inflammatory disease then look no further! Great review by @tomdbutler and Aala @Time_MCR
On BBC radio 4,Dr Gareth Kitchen shared with us insights on his latest publication in Anaesthesia: bbc.co.uk/sounds/play/m002pp…