Scientist @HumboldtUni | Engineer | #Data cruncher | Improving health with #clocks | #SciComm | #TheoryInPractice | #OpenScience | @timelyscientist.bsky.social
Berlin, Germany
Joined November 2017
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Some of my thoughts on what is and what isn't possible in -omics #circadian #analysis in #JBR.
👉tinyurl.com/26ur32jw
Discussion and controversy welcome 😉
Thank you @reactome for highlighting our recent work (buff.ly/jLV9oif )in PloS Biology as the "Reactome Research Spotlight" on the website.
#circadian #circadianmedicine #clock #cancer
ML uncovers 24h rhythms in cancer 🕒🧬
Using COFE ☕, we reconstruct #circadian rhythms from human tumor biopsies across 11 #cancer types!
Turns out, tumor #clocks tick in a different timezone 🕰️💊
in PLoS Biology 👉 buff.ly/hwx7wNe
#Chronotherapy #CircadianMedicine
🚀 Glad to contribute to this study led by @BraintimeLab, where we explored why organisms prefer networks of autonomous #clocks over a single central oscillator, proposing enhanced robustness, specialization, and adaptability. 👇
🙏DFG for funding
#circadian #circadianmedicine
Circadian clocks in the body likely 'entrain' themselves rather than hierarchically reset. Given internal cellular feedback, omics (Bharath @TimelyScientist) may accurately predict their phases via connectomics, something single-gene reporters cannot. doi.org/10.1016/j.sleep.2025…
Enhance your academic paper reading by using Google Scholar's PDF viewer. Set it as your default PDF reader in Chrome for AI-generated section summaries with ease. Give it a try: buff.ly/Ixtx5db #ResearchTool #AcademicTwitter
Do you know a better tool? Let me know.
🚨New preprint alert!🚨 Our latest study (with @clocklab_IGFL & Y. Suzuki) on post-transcriptional #circadian regulation
🔬 Key finding: #Clock proteins regulate #splicing of non-rhythmic transcripts too
Read it here 👉 buff.ly/UUwPR0Y
#omics #ScienceTwitter #Nanopore
Happy Pi day with a license to be irrational 😜! We #circadian #rhythm nerds love *pi* as it is intimately connected to circles, #cycles and #clocks 👇!
#idm314 #MathIsEverywhere #STEM #PiDay2025 #3Point14
Did you know your brain clock is the source of jetlag? It's Brain Awareness Week! Beyond its key roles, the brain's #circadian rhythm supports health through regular rest & sunlight. Celebrate the brain's wonders & nurture its health. #BrainAwareness #MindHealth
This book argues that generalists excel over specialists in solving #complex #realworld issues. Diverse perspectives and #creativity are key when there’s no clear optimal solution. It’s changed my view as a teacher, researcher, and parent. Highly recommend! #ProblemSolving
193y ago, Charles #Darwin set sail on the HMS Beagle on his 5 year geological voyage that resulted in the #theory of #evolution.
Listen to the chaotic and funny start to the voyage on 27 Dec 1831 in one of my favorite podcasts @TheRestHistory :
open.spotify.com/episode/5u0…
Bharath Ananthasubramaniam retweeted
“Ten years ago I was kicked out and forced to retire.”
Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges.
Ten years ago, Karikó was still doing all her experiments by hand but today she has been awarded the medicine prize for her research on mRNA, which led to the development of COVID-19 vaccines.
Listen now:
Bharath Ananthasubramaniam retweeted
When is a rhythm functional? @TimelyScientist poses the question of significance vs biological relevance in biological rhythm detection #JBR:
buff.ly/3EVETsB
A little of everything I like....#mathmodelling #dataanalysis #Biology insights and of course #clocks
Period and phase are not the same; but what do they mean for synchronization?
frontiersin.org/articles/10.…
Bharath Ananthasubramaniam retweeted
While 40% of teens report being night owls, the number jumps to 80% in those with #depression. A new intervention from @UCSF researchers helps kids adjust to their natural sleep-cycle rhythms, which could improve depression symptoms. ow.ly/ofYB50PLBnz
Bharath Ananthasubramaniam retweeted
Feeling Tired? 4 Ways to Fix Your Sleep Schedule and Reset Before Fall - WSJ wsj.com/health/wellness/slee…
I'm all for facilitating #data #sharing and #reproducibility (especially in #circadian and #sleep research). Here are some great ideas to achieve that using something as simple as structured README files from @A_J_Millar and colleagues.
mdpi.com/2624-5175/5/3/33
#clock #rhythm
🚨If you want to learn some new #DataScience skills or brush up your old ones,
@DataCamp is have all their courses available for free for a week -- I use these courses for teaching and the students seem to really like them.
datacamp.com/freeweek
Bharath Ananthasubramaniam retweeted
Excited to share our newest paper in Nature Reviews Cardiology @NatRevCardiol - #CircadianMedicine can improve MI (heart attack) healing, help CUCU/ICU patients lead longer & healthier lives. LINK below & please RETWEET!
nature.com/articles/s41569-0…
#mathmodelling approach to understanding physiological #oscillations.
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Bharath Ananthasubramaniam retweeted
Our new paper by @Jjiyeon_lee is out in @NatureComms! She shows that circadian protein REV-ERBa regulates microglial lipid droplets and tau pathology, and that LDs inhibit microglial tau phagocytosis. Clock genes, microglia, lipid droplets, and tauopathy!
nature.com/articles/s41467-0… – at Berkeley, MO
This is very interesting 👏. I wonder if this would be more accurate if the comparison can be made within subject longitudinally?
Out today: Temperature biorhythms predict disease risk nature.com/articles/s41467-0…