Michael Perry retweeted
Mark Cuban's Cost Plus Drugs is a good example of what actually drives change in healthcare costs. His company charges a flat 15% markup on more than 4000 drugs and showing everyone the price.
That's it. No new law, no new agency.
And his company has forced incumbents to change prices in a way decades of policy never did.
So much of our system only works because nobody can see the prices. Transparency is wildly underrated as health policy!
teapaw.org/a16z/status/2115456219…
Mark Cuban scaled Cost Plus Drugs from about 100 generics to roughly 4,000 at a flat 15% markup, forcing incumbents to change prices in ways decades of policy never did.
He thinks AI could transform healthcare, but it won't fix opaque prices and broken incentives on its own.
Mark sits down with a16z's Julie Yoo and Erik Torenberg to discuss what he's learned building Cost Plus Drugs, why trust is its core product, and how greater transparency could put pressure on healthcare costs.
They also explore why drugs designed for your DNA could cost close to nothing, the football field-sized drug plant his team shrank into tractor trailer-sized pods, his plan to make generics in Dallas for less than he pays manufacturers in India, and why every company will either be great at AI or go out of business.
0:50 Cost Plus beat decades of policy
3:15 111 generics to 4,000 drugs
5:00 A drug plant shrunk to 5K sq ft
5:55 $20M drug factories in a trailer
8:10 Hospital deals with zero denials
9:50 Why health plans are rigged
14:05 1,335 pages no human can check
18:35 "Where are they f**king me over?"
22:45 Making drugs cheaper than India
26:50 Why you still need entry-level hires
31:45 Nonprofit hospitals must offer aid
35:55 DNA-matched drugs for near $0
39:30 Why AI will mean more doctors
48:00 Mark's plan: "bye bye insurers"
52:25 Why AI labs' ads are useless
56:35 Get good at AI or go out of business
YouTube: youtu.be/5UWDUD6qaM4
@mcuban @julesyoo @eriktorenberg
Michael Perry retweeted
A Warning We Cannot Afford to Ignore: Cybersecurity and the Threat to Life Safety Systems
Reports of refrigeration system failures at multiple U.S. military commissaries are now under investigation for possible cyber interference. The immediate concern is spoiled food and disrupted operations, but my concern goes considerably further.
Food can be replaced. People cannot.
Think about the implications for fire and life safety systems. Fire pumps, smoke control, emergency ventilation, access controls, and other critical infrastructure increasingly incorporate networked technology. Properly engineered systems should have independent controls, safeguards, and manual overrides, but those protections are only as good as the design, maintenance, and testing behind them.
If multiple installations share vulnerable controllers, software, or remote access infrastructure, we have the potential for common-mode failures across geographically separated facilities. That is an engineering and security problem with consequences far beyond a commissary freezer.
We do not yet know whether these incidents were malicious. What I want to know is whether investigators are examining the broader facility control architecture and identifying other systems that could be exposed.
A freezer full of spoiled meat is expensive. A compromised fire or life safety system could be catastrophic.
This is a warning that must be heeded and a lesson that must be learned. We cannot afford to wait until lives are lost to address vulnerabilities we already know exist.
Michael Perry retweeted
The story keeps getting crazier. To recap everything that has been reported so far:
- The US intelligence community discovered that Jensen Huang, the CEO of the largest company in the world, was sleeping with Alice Huang, a Chinese spy and an executive at Megaspeed. (FT)
- Multiple independent investigations have concluded that Megaspeed is likely a Chinese cutout, which helps Chinese companies access AI chips or circumvent export controls. (NYT and Bloomberg)
- The US intelligence community also concluded that Alice Huang’s goal was to convince Jensen to lobby the U.S. government to loosen export controls on advanced AI chips. (NYT)
- The intelligence community relayed this information to “a small group of top US government officials” earlier this year. (FT)
- Over the last year, Jensen Huang has repeatedly lobbied the U.S. government to loosen export controls on advanced chips. @BISgov has done so, not only by permitting the export of H200 chips to China, but also not enforcing export controls that would have required a license for exports of the most advanced Blackwell chips to Megaspeed and Southeast Asia.
- Although @CommerceGov leadership was presumably briefed on this information by the U.S. intelligence community, @BISgov has taken no actions to tighten controls on Megaspeed or Southeast Asia.
- Megaspeed remains a preferred cloud partner of Nvidia, and continues to receive Nvidia Blackwell chips despite employing a Chinese spy who reportedly is romantically engaged with the CEO of Nvidia.
- Tens of billions of dollars worth of AI chips have been exported to Southeast Asia this year alone, and Malaysia and Singapore are now two of the four largest importers of AI chips in the world.
What is going on here??? We need answers. The question of who gets the most advanced AI chips in the world is literally the defining strategic question of our time. And not only does it seem like the MSS may be directly influencing the debate on export controls in the United States, but also @CommerceGov is refusing to listen to the warnings of the IC on this issue. What is a POSSIBLE good explanation for why Megaspeed is still receiving chips? Why is there not a license requirement for AI chip shipments to all of Southeast Asia? This is beyond strange at this point.
The fallout from this story will be massive. Obviously, the motivations underpinning Nvidia’s policy views opposing export controls must now all be questioned. But also, how did @BISgov sit on this information and has still taken no actions? We need answers.
US intelligence agencies believe @Nvidia CEO Jensen Huang had romantic relationship with alleged Chinese spy
as.ft.com/r/97c2f9f7-ad2e-44…
Michael Perry retweeted
Now available for preorder in the US! THE CASTLE, coming from @AtriaBooks on May 11, 2027. simonandschuster.biz/books/T…
Michael Perry retweeted
Ramaswamy has produced an attack ad weaponizing the rape of his opponent, Amy Acton, when she was 12 years old. It features Acton’s mother, who abandoned Acton after she was raped by her step-father, fleeing the state with her husband.
Here is the corporate money helping fund that ad.
Michael Perry retweeted
Dear Secretary Bessent @SecScottBessent,
My name is Everett Stern. In 2010 I was a compliance officer at @HSBC. From a back office in New Castle, Delaware, I watched billions of dollars move to drug cartels, sanctioned regimes, and terrorist organizations. The enemies of the United States. I documented it, I escalated it, and when the bank would not act, I took it to the @FBI, the @CIA, and eventually the @SECGov.
The result was a $1.92 billion settlement. At the time, it was one of the largest in American history. It was also about five weeks of the bank’s profit. Not one banker was charged. Not one went to prison.
I paid a different price. I lost my career, my savings, and my place in the industry I had trained for. I was blacklisted. Every door in American finance closed at once. I slept on a camping cot in a 300 square foot apartment because I could not afford a bed, and I waited tables at @PFChangs to eat. I tell you this not for sympathy, but so you understand that I know exactly what it costs to do the right thing in American finance, and exactly how little the system does in return.
I made that sacrifice because I believed it would change something.
Yesterday, your department fined @BankofAmerica $1.2 billion for failing to report more than $5 billion in suspicious transactions, some of it tied by your own findings to Chinese laundering networks, narcotics, and the southwest border, alongside 475 apparent sanctions violations touching Russia, Iran, and global terrorism. The bank admitted it willfully violated the Bank Secrecy Act.
Fourteen years after HSBC. A bank with “America” in its name. And once again, not one individual charged.
Secretary Bessent, I want to say plainly what I believe you already know. The fines are not working.
A fine is paid by shareholders, absorbed by the balance sheet, and forgotten by the next earnings call. Bank of America reported earnings this morning. Nobody who set the alert thresholds, nobody who decided the 2024 cease and desist could wait, nobody who chose the backlog over the law will lose a single thing they value. Their lives are untouched. That is the entire reason the behavior repeats.
This is money laundering. This is blood money. Money that reaches a cartel buys fentanyl that kills Americans. Money that reaches a terrorist organization buys the next attack. This country has fought a war on drugs and a war on terror for decades, at enormous cost in lives and treasure, and all the while we have allowed the financing to flow through institutions we charter and regulate. Cut off the money and we win. We have never seriously tried.
There is also a question of equal justice that I cannot let go.
Before I walked into the FBI building to report HSBC, I stopped in front of the Great Seal on the wall and read the words engraved beneath it: “Justice is the defense of our liberty.” I believed that. I still want to. But every day in this country, people go to prison for crimes that are nothing next to moving money for the people who want Americans dead. A suit, a title, and a corporate badge should not be a shield from the consequences that apply to everyone else. If a street dealer goes to prison for what he sells, the banker who moved the cartel’s money should be standing next to him.
I also want to raise something that is rarely said in these conversations. Why has no one inside Bank of America come forward the way I did? The answer is that everyone in American banking knows what happened to me, and to the whistleblowers who came after. The last person who spoke up is the only policy anyone believes. That is a culture problem, and it starts with leadership, in the banks and in the agencies that regulate them.
This is not a political issue. It has spanned administrations of both parties. It is a national security issue, and I am asking you to treat it as one.
Three things would change the math overnight.
Refer individuals for criminal prosecution. Not the analyst in the queue. The executives who set the thresholds and chose the risk. One banker in handcuffs would do more than every fine in Treasury’s history combined.
End “too big to jail.” An institution cannot be too big to fail and too big to jail at the same time. If it is the first, it must be held to a higher standard, not a lower one.
And if Bank of America will not act as America’s bank, review its charter. A national charter is a privilege granted on behalf of the American people. It should be conditioned on not moving money for the people trying to kill them.
Secretary Bessent, you said yesterday that these actions send a clear message that even the biggest institutions are not above the law. With respect, the institution was never the problem. The people inside it are above the law, and they know it. Until that changes, I will keep writing letters like this one, and the next bank will keep paying the next fine.
I gave up everything I had to stop this. I am asking you to use the power you have to finish it.
Respectfully,
Everett A. Stern
HSBC Whistleblower
Founder and Intelligence Director, Tactical Rabbit
Michael Perry retweeted
On the Cornell 7 and Jane Doe: I don't know if anyone reads or follows LA Magazine? I don't.
But they have been intensely covering the situation, and failed to publicly disclosed what is a glaring conflict of interest, while promising a "bombshell" to come.
The attorney for Winston Lee, one of the Cornell 7 who is from a very prominent and wealthy South Korean family (his grandfather is a former prime minister), has hired Teny Geragos, a high profile attorney, to represent him.
The co-owner of LA Magazine is Mark Geragos, Teny's dad. Their relationship has not been publicly disclosed as a conflict of interest in their coverage. One of the LA Magazine reporters is promising a "bombshell" to discredit Jane Doe. Just making you all aware.
H/t to David Denney for bringing this to my attention.
Michael Perry retweeted
Don’t let them gaslight you about Social Security. The federal government currently owes Social Security roughly $2.6 TRILLION.
For decades, Social Security surpluses were invested in Treasury securities, allowing Treasury to use that cash for other federal financing while promising repayment with interest.
Social Security didn’t create the national debt.
It has been one of the federal government’s creditors.
They are stealing our money and then blaming the American people.
~We are the 99
Michael Perry retweeted
Mike Krukow on the Giants Biggest Areas to Improve
Presented by Fieldwork
#mlb #sfgiants #sanfranciscogiants #mikekrukow
Michael Perry retweeted
Replying to @AnthonyAguero
A foreign account with A.I generated videos. This shit is hilarious 🤣
Michael Perry retweeted
The holy shit moment of the story:
“The shipment included one of the jet’s canopies, which covers the cockpit and contains stealth technology that only the U.S. and its allies have access to, according to two of the people. An adversary could study the parts and potentially reverse-engineer the prized technology if it had one of the canopies.”
Hill investigates after F-35 parts diverted to Hong Kong dlvr.it/TVXrgC
Michael Perry retweeted
If Sam Altman, Dario Amodei, and Elon Musk all agree that we have to slow down - and now - something serious clearly happened with a frontier AI model.
Journalists should be digging in to this. We aren’t getting the whole story here.
Michael Perry retweeted
The sister of the Republican candidate for governor of Maine Bobby Charles, just endorsed Democrat Hannah Pingree in one of the most brutal Op-Eds I’ve ever seen.
Yikes.
Michael Perry retweeted
Replying to @GBC_Press
Michael Perry retweeted
Are we seriously still debating raising the retirement age and cutting benefits for working people to keep Social Security solvent while someone earning $1 million stops paying Social Security tax after their first $184,500 in wages? C’mon, bro.
Michael Perry retweeted
Every market has a fellow who is certain the prices are wrong and that he alone knows the right ones. Usually the market charges him tuition for this belief. Occasionally, it hands him the Treasury.
Consider the record. In 2000, Scott Bessent left Soros to run $1 billion of his own. Five years later, the fund no longer existed. In 2015 he tried again with Key Square, co-founded with Soros alum Michael Germino and seeded with $2 billion of Soros money — which is a bit like failing your driving test and being handed a Ferrari. Assets peaked at $5.1 billion in 2017 and finished 2023 at $577 million. Institutional investors reportedly went from 180 to 20, a retention rate that would embarrass a gym in February. And in 2018, Soros — the man who staked him — took his chips off the table. When your own anchor investor would rather not watch, that is not typically a buy signal.
Which brings us to the question: is the man now confidently dictating where oil, the dollar, Treasury yields, and stocks ought to trade a macro mastermind the market tragically failed to appreciate? Or did the market spend two decades doing its due diligence on him — and sell? He believes he’s smarter than the market. The market already graded that exam. Twice.
Michael Perry retweeted
Replying to @ZavalaA
The state emailed a reporter asking her to change her tone for covering this story. That is the part to remember. When officials start coaching journalists instead of answering questions, the story is always bigger than the tires. Keep reporting it straight.
































