Toronto, Canada
Joined September 2019
Toronto Immune and Digestive Health Institute retweeted
Ultra-processed foods trigger a bigger insulin response than less-processed ones, even when they contain identical calories and nutrients. When people consumed two different meals matched closely for protein, carbs, fat, and fiber, the ultra-processed one produced a larger insulin response despite a similar overall blood glucose response. It also blunted the normal shift toward burning carbohydrates after eating and changed the brain's response to eating. I’ve talked before about Kevin Hall’s trial, where people eating an ultra-processed diet consumed about 500 extra calories per day and gained weight. This new study explains another part of why UPFs are so problematic - it shows that the way food is processed can change how our bodies handle it and even how our brains perceive it!
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Toronto Immune and Digestive Health Institute retweeted
Attn. General Surgeons, fellows, residents, PAs: Join us Sat.,Nov.7 for 2026 OAGS Surgical Symposium #TorontoOntario🍁 Early bird registration exp: Oct 24. Hotel rate expires today: Oct.16. (final ext.) Details/Reg:rebrand.ly/e4ti4n7 #OAGS2026 #generalsurgery #meded
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Toronto Immune and Digestive Health Institute retweeted
1/7 85-86% of IBD patients in remission report food intolerances, versus 33% of controls. A Gastroenterology paper argues inflammation causes this: colitis depletes the bacteria that digest dairy proteins, and colonic mast cells do the rest. gastrojournal.org/article/S0…
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Toronto Immune and Digestive Health Institute retweeted
In this episode of Bottom Line, Jocelyn Laidlaw speaks with Manitoba oncologist Dr. Ralph Wong about rising colorectal cancer rates in younger Canadians, symptoms to watch for, later-stage diagnoses, and why screening should start at 45. Watch: youtu.be/KZjEiqDfdjE
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Toronto Immune and Digestive Health Institute retweeted
Part three of the IBD pipeline series. Not just what’s coming... but when. I’ve mapped every phase 3 trial in UC and Crohn’s against ClinicalTrials.gov. Start date to primary completion. Company and NCT number for each. 16 phase 3 studies still to complete. 12 of them are due in 2028. All three anti-TL1As (the first wave - there are others stacking up behind). Oral IL-23R (icotrokinra) in UC and Crohn’s. Co-formulated gus + golimumab. Mirikizumab plus tirzepatide. Two have already delivered (*press release only as of today). Obefazimod: positive phase 3 in UC, US filing planned for Q4. Tulisokibart: positive UC induction study in June. Next up... afimkibart in UC, due to complete about now. Most of these are recruiting today. Every patient we offer a trial brings 2028 closer.
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Toronto Immune and Digestive Health Institute retweeted
Part four of the IBD pipeline series - phase 2. 22 programmes to watch in UC and Crohn's. Start to primary completion, company and NCT number for each. 12 of them are due to complete by the end of 2027. And some of it lands NEXT WEEK at UEG in Barcelona. Sunday: Spyre's three long-acting antibodies in UC Monday: first data for Gilead's oral α4β7 (emvistegrast)... and risankizumab plus an anti-α4β7 in Crohn's (ABBV-466). Both late-breakers. Tuesday: RIPK2 (OD-001), PSGL-1 (ALTB-268) and an anti-fibrotic for stricturing Crohn's (ontunisertib) Three have passed primary completion with nothing out yet. Zasocitinib in UC (Takeda says data by March 2027). Eltrekibart (Lilly). AZD7798 (AstraZeneca). [1 of 3]
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Toronto Immune and Digestive Health Institute retweeted
How can Canada build a stronger clinical trials system now? Join experts for a panel on practical solutions, national alignment, and collaboration to accelerate innovation across Canada. 🔗 tinyurl.com/PACT-2026
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Toronto Immune and Digestive Health Institute retweeted
Boom RCT💥 in @AGA_Gastro Home calpro monitoring didnt reduce UC flare risk. Blow to UC monitoring/T2T? More likely reflects need for mandated intervention (not doctor discertion) and for effortless monitoring methods (not often-skipped poop handling) share.google/izEYhHmJhGrUaXV…
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Toronto Immune and Digestive Health Institute retweeted
👧 In children with acute severe #ulcerativecolitis, intestinal ultrasound helped identify patients unlikely to respond to first-line therapy and at higher risk for colectomy. 🔗 ow.ly/o5Rr50ZwBkk #PedsGI
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Toronto Immune and Digestive Health Institute retweeted
Your best trial starts with the right people. From global pharmaceutical companies to emerging biotechs, Alimentiv brings scientific rigor, operational excellence, and authentic collaboration to every program we touch. Find out how we can help advance your program, wherever you are in your pipeline 👉 loom.ly/xyE2kRE #ClinicalResearch #Gastroenterology #GIIsOurWhy
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Toronto Immune and Digestive Health Institute retweeted
A diet with <1 ultraprocessed food serving/day is associated with a 50% reduced 20-year IBD risk in Western populations ✅ The lowest consumption of ultraprocessed foods, the lowest risk of IBD ✅ The negative impact may be mediated by: 🔸 Disruption of the gut microbiome 🔸 ⬆️ intestinal permeability from additives such as emulsifiers (eg, carboxymethylcellulose) and preservatives ✅ ⬇️ UPF consumption could help mitigate the rising global burden of IBD 📚 Read the full research from @NarulaNeeraj & colleagues in @AGA_Gastro: gastrojournal.org/article/S0…
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Toronto Immune and Digestive Health Institute retweeted
Colorectal Cancer Canada is proud to have signed the Canadian Cancer and Work Charter. By joining this movement, we are dedicated to ensuring no one faces cancer alone in the workplace. Learn more at: cancerandwork.ca
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Toronto Immune and Digestive Health Institute retweeted
You can’t always see IBD—but it impacts everything. Victoria Tyler is an influencer and patient advocate living with ulcerative colitis and a permanent ostomy—and she’s using her platform to speak openly about what life with IBD really looks like. She’s turning her experience into something others can see, understand, and talk about. Watch her story and visit: bit.ly/4eJtezE for more stories from people living with IBD and resources.
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Toronto Immune and Digestive Health Institute retweeted
Drink your coffee black (no additives) if you want the full health benefits. 2-3 cups per day has been associated with a 25% reduction in all-cause mortality. That benefit goes away when cream and/or sugar are added. I think this happens for a few reasons: • Dairy proteins can bind to coffee’s antioxidants and polyphenols and slow their absorption. • Heavy cream, butter, and MCT-heavy coffee don’t necessarily block coffee polyphenols, but they can add substantial saturated fat and calories. For someone watching ApoB or LDL-C, this can work against the very cardiovascular benefits they’re hoping to get from coffee.
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Toronto Immune and Digestive Health Institute retweeted
📣 Join the upcoming @D_ECCO_IBD webinar on the role of diet in #IBD prevention ✅ Animal vs plant protein in IBD ✅ Lights and shadows of ultraprocessed foods in the onset of IBD ✅ To fiber or not to fiber in IBD ✅ Dietary patterns during early lige and IBD risk 📆 24 June ⏰ 18:00-19:20 (CEST) 🎓@VaioSvolos, @sarbagili, @Alice_APD, @vds_julie1 & Alicia Sandall ECCO membership is needed for registration 👉🏻 Access the full program and register here: ecco-ibd.eu/education/webina…
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Every day is #IBD day for the Team at TIDHI. It’s why we exist! #WorldIBDDay
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Toronto Immune and Digestive Health Institute retweeted
Replying to @TorDigHealthIns
@TorDigHealthIns team is excited to join the Gutsy Walk 2026! 👏 We’re proud to support the IBD community through patient care, research, and advocacy. Every donation helps make a difference for those living with Crohn’s disease and ulcerative colitis 💜 crohnsandcolitiscanada.akara…
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Toronto Immune and Digestive Health Institute retweeted
Ontario becomes the second province to change the colorectal cancer screening age from 50 to 45. Coming in effect on July 1st, it will now be possible for a wider reach of Ontarians to qualify and be provided with a colorectal cancer test kit and the possibility of colonoscopies.
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