@TrujilloLab

Fascinated by ubiquitination. Located at the University of Hamburg. Tweets are my own. @trujillolab.bsky.social

 Hamburg, Germany
trujillolab.com
Joined August 2011
  • Tweets3.9K
  • Following1.8K
  • Followers2.4K
279Media
Endogenous molecular glue acts as a signal in human cells - akin to auxin! Metabolite glues as a means of purine sensing and chemotherapeutic response nature.com/articles/s41586-0…

Metabolite glues as a means of purine sensing and chemotherapeutic response

Nature - Purines can act as endogenous molecular glues in human cells by anchoring a rate-limiting enzyme in purine biosynthesis to its inhibitor, and modifying this mechanism could provide a way...

nature.com
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FYI Blue-light inducued phosphoproteome analysis in #Marchantia, and MpPHOT related contents can be also found in the following studies. doi.org/10.1093/pcp/pcz232 doi.org/10.1016/j.cub.2023.0…

Regulation of Photosynthetic Carbohydrate Metabolism by a Raf-Like Kinase in the Liverwort Marcha...

Abstract. To optimize growth and development, plants monitor photosynthetic activities and appropriately regulate various cellular processes. However, sign

academic.oup.com
TrendsPlantSci@TrendsPlantSciJun 22
Phosphorylation blues: Cracking the phototropin phosphocode dlvr.it/TT958C #plantscience
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Yansong Miao Lab@MiaoYansongMay 21
Excited to share our newly published "A Multidimensional View of Biomolecular Condensates in Plant Biology" in the Annual Review of Plant Biology! We discuss emerging mechanisms, biological functions, and future directions. 🌱🔬 - go.shr.lc/43rf7Zj

A Multidimensional View of Biomolecular Condensates in Plant Biology

Biomolecular condensates have emerged as versatile regulators of plant cellular processes, offering a dynamic and reversible mechanism to coordinate development, stress response, and spatial organi...

annualreviews.org
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Mauricio Contreras
@mpcontreras4May 20
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇 biorxiv.org/content/10.64898…
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Sophien Kamoun
@KamounLabMay 21
Just published: The Hidden Handshake: How AlphaFold Solved a Decade-Long Mystery in Plant Immunity Over ten years in the making - generations of students and postdocs, countless false starts, and others were chasing this too. Here's the structural basis of NLR activate-and-release, and, yes, we can engineer it. medium.com/p/the-hidden-hand…

The Hidden Handshake: How AlphaFold Solved a Decade-Long Mystery in Plant Immunity

Over ten years in the making — generations of students and postdocs, countless false starts, and others were chasing this too. Here’s the…

kamounlab.medium.com
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Alga Zuccaro@Team_ZuccaroMay 20
Really proud of this collaborative work exploring how fungal effectors exploit prion-like domains to access plastids and influence plant metabolism during symbiosis. Great to see the PEPSI–DXR story come together. @neto_flames @JohanaMisas @TheVilchezLab biorxiv.org/content/10.64898…
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🚨 Paper out now in #ScienceAdvances @ScienceMagazine 🌱🦠 Pathogens don’t just target protein degradation—they also hijack host translation. "Bacteria use P-body condensates to attenuate host translation during infection" ⚖️♻️ science.org/doi/10.1126/scia…
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Prof. Keiko Torii
@KeikoUToriiApr 4
新作です!  植物の気孔の数を決める受容体キナーゼERECTAのK63ユビキチン修飾部位を同定。修飾不可な受容体は細胞膜上に残存するため活性が亢進し、その結果、気孔の数が減少することを示しました。おめでとう@NewPhyt 🥳🌱 nph.onlinelibrary.wiley.com/…
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Pinner and Dietz made DNA origami shells which mimic biological clathrin proteins by grabbing onto lipid membranes and pulling out roughly spherical buds! Link "Programmable DNA shell scaffolds for directional membrane budding": nature.com/articles/s41467-0…
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Alga Zuccaro@Team_ZuccaroApr 1
Really proud of this work led by Ruben Eichfeld! We show how a CBM domain gain/loss can rewire fungal chitinases, turning them from antifungal enzymes into immune-suppressing effectors that support plant symbiosis. nature.com/articles/s41467-0…
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Super interesting work! UFMylation moving up from a local ribosome repair signal to a systems-level coordinator of ER-nucleus #proteostasis
Yasin Dagdas@PlantoPhagyMar 31
New #preprint 😍‼️ led by 2 incredible postdocs Ni Zhan & @ranjithbio: transforming #UFMylation from a local ribosome rescue pathway to systems level regulator of mRNA splicing biorxiv.org/content/10.64898… A short 🧵
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Interesting paper on the degradation of DELLAS (gibberellin pathway) by a plasma membrane localized E3 ubiquitin ligase to regulate growth under C/N imbalance #proteostasis academic.oup.com/plcell/arti…
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Bruno Ngou@BrunoNgouMar 24
Cell-surface receptors play key roles across many biological processes. In plants, these receptor families have undergone remarkable expansion. Here, we systematically review these receptors in @ThePlantJournal. Happy to see this out! onlinelibrary.wiley.com/doi/…

Plant cell surface receptors

Plant cell surface receptors have evolved to perceive peptides, proteins, glycans, lipids, and small molecules through diverse ectodomains, integrating these inputs into distinct physiological...

onlinelibrary.wiley.com
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Yasuhiro Kadota@Yasu0407Mar 23
New review out! This might be the most up-to-date textbook on plant surface receptors and signaling. Great job, @BrunoNgou ! dx.doi.org/10.1111/tpj.70800

Plant cell surface receptors

Plant cell surface receptors have evolved to perceive peptides, proteins, glycans, lipids, and small molecules through diverse ectodomains, integrating these inputs into distinct physiological...

onlinelibrary.wiley.com
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Samaj Lab@Samaj_labMar 16
Plant MAPKs: Killers or protectors? Find more here: sciencedirect.com/science/ar…
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Panagiotis Sarris@PanosSarrisMar 15
Targeting redundant gene families: A multiplexed, tissue-specific CRISPR toolbox for Arabidopsis genetic screens. cell.com/cell-reports/fullte…

Targeting redundant gene families: A multiplexed, tissue-specific CRISPR toolbox for Arabidopsis...

Anfang et al. present a tissue-specific, multiplexed CRISPR toolbox for plants that uses paired sgRNAs and barcoded libraries to target redundant gene families. Applied to Arabidopsis nutrient...

cell.com
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Alga Zuccaro@Team_ZuccaroFeb 18
We are pleased to announce that CEPLAS has open research positions for both doctoral and postdoctoral researchers. Please help in spreading the word: ceplas.eu/en/training-career…
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Looking forward to visiting Taiwan and meeting alumni Ooi-Kock Teh now group leader @AcadSinica ipmb.sinica.edu.tw/en/people…
IPMB Academia Sinica (中研院植微所)@IPMBSinicaFeb 13
[@IPMBSinica Seminar] 2026-02-25 10:30; A134, Ag Tech Bldg Speaker：Prof. Marco Trujillo @TrujilloLab (Head, Department of Plant Immune Biology, University of Hamburg, Germany) Title：Protein homeostasis networks - challenges and opportunities for stressed plants
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Exciting work from @SpoelLab Ubiquitin recognition integrates plant immune signaling by cell-surface and intracellular receptors @PPStasis biorxiv.org/content/10.64898…
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The proteasome organization into fibers and other supramolecular arrangements contributes to its regulation #yeast sciencedirect.com/science/ar…
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