plant natural product (bio)chemist between UK and Shanghai. Greek and Olympiacos. opinions ARE my OWN.
Norwich, Norfolk, England
Joined April 2012
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Many thanks to @AnneOsbourn1 and @v_courdavault for the invitation to contribute in the themed issue on Physiology and metabolism 2024 of Current Opinion in Plant Biology for Specialised metabolism in Hypericum sciencedirect.com/science/ar…
Vangelis Tatsis retweeted
Single-cell RNA sequencing facilitates the elucidation of the complete biosynthesis of the antidepressant hyperforin in St. John’s wort
hubs.li/Q02NjCWx0
September featured research article from #MolecularPlant
@MPlantPCom #plantsciences
plantae.org/single-cell-tran… thank you @thdpaepe for your nice spotlight!
Single cell transcriptomics aids gene discovery of complex natural product biosynthesis plantae.org/?p=136017
Vangelis Tatsis retweeted
Plant Science Research Weekly: Sept 6, 2024 plantae.org/plant-science-re… Review: Naming plasma membrane domains; Composite auxin response elements; De-Ub of HY5 promotes photomorphogenesis; Single cell transcriptomics of St. John’s wort (1/2)
ALT The bioactive compound hyperforin is produced in a small number of cells called Hyper cells. Single cell transcriptomics revealed the final steps of the biosynthesis of this compound in St John's wort.
Vangelis Tatsis retweeted
Single cell RNA sequencing facilitates the elucidation of the complete biosynthesis of the antidepressant hyperforin in St. John’s wort. #research #MolecularPlant cell.com/molecular-plant/abs…
Vangelis Tatsis retweeted
55 years ago, the first humans landed on the surface of another world, when the #Apollo11 lunar module touched down on the Moon.
On #NationalMoonDay, take a look back at a special issue of Science that celebrated the lander's landing: scim.ag/7JQ
And after almost 20 years from my PhD the personal quest on hyperforin biosynthesis has ended. From PhD student to PhD supervisor. I don’t know if I did well but I feel fullfilled.
Congratulations to my student and from now on Dr Zhuo Wang for her successful PhD defence!
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Vangelis Tatsis retweeted
Please join the group! We work on all aspects on plant specialised metaboism including gene discovery, biosynthesis, evolution and even applications e.g. biocatalysis and SynBio
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Vangelis Tatsis retweeted
Arginine Kinase Activates Arginine for Phosphorylation by Pyramidalization and Polarization (Great work deserves promotion, even though all the corresponding authors are twitterless, nevermind the last author Mike Blackburn is 90 years old) @acscatalysis pubs.acs.org/doi/10.1021/acs…
Ok the authors most likely are unable to speak and write properly in English to understand their mistake. But the editors and the reviewers have they read the first sentence of introduction?
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Vangelis Tatsis retweeted
Η ΚΑΕ Ολυμπιακός συγχαίρει τον μεγάλο δημιουργό του σινεμά, Γιώργο Λάνθιμο, για την τεράστια επιτυχία της ταινίας του "Poor Things", η οποία απέσπασε συνολικά τέσσερα Οσκαρ! #Oscars #PoorThings
ΤΡΑΓΩΔΙΑ -ΤΕΜΠΗ 2023 - Sign the Petition! chng.it/FWv5Lrb6 via @Change
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Vangelis Tatsis retweeted
Read our latest research @UoMMIB on the effect of phosphorylation on #RAS GTPase and capturing the first truly "closed" conformation in X-ray crystallography structures, thanks to BeF3- metal fluoride complex, published with @SpringerNature @CommsChem
rdcu.be/dxr9o
Vangelis Tatsis retweeted
Single-Cell RNA-seq based elucidation of the antidepressant hyperforin biosynthesis de novo in St. John's wort. biorxiv.org/cgi/content/shor… #biorxiv_plants
This is the latest work from our group, we elucidated the biosynthesis of hyperforin biorxiv.org/content/10.1101/…
The genes for the synthesis of polyketide were solely expressed in a particular minor cluster of cells. Looking carefully we saw that we had high expression of MEP pathway genes suppling the prenyl groups and of four prenyltranferases. We tested every one of them in yeast.
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