@VillaltaLab

Muscle immunologist aiming to understand how immune cells aid in muscle homeostasis and immune dysregulation contributes to disease

 Univer. of California Irvine
immunology.uci.edu/ifi-faculty-profile/?smid=1197
Joined June 2017
  • Tweets148
  • Following390
  • Followers249
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instagram.com/reel/DG3AZeZP5…

Erica Lynn (@iamthecookieboss) • Instagram reel

instagram.com
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Armando Villalta retweeted
Nicolas Dumont@DumontN_Lab15 Dec 2023
Our lab is looking for PhD or post-doc (fully funded positions) to work on projects related to stem cells and myopathies. Please spread the word and re-tweet 🙏. DM me or email me if interested. #myotwitter
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We are seeking a molecular biologist to work on chimeric antigen receptors. Email me at [email protected] if interested. More detail below: jobrxiv.org/job/university-o…

Molecular Biologist - Chimeric Antigen Receptors

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobrxiv.org
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Armando Villalta retweeted
Mike Hicks@Mic_Hicks13 Jul 2023
First paper out from the lab: SIX1+PAX3+ identify a progenitor for myogenic lineage commitment from hPSCs journals.biologists.com/dev/…

SIX1+PAX3+ identify a progenitor for myogenic lineage commitment from hPSCs

Summary: This study defines specific steps to generate more robust and predictable myogenic cells from human pluripotent stem cells and explores the regulation of SIX1 in early myogenic commitment.

journals.biologists.com
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Replying to @RicMG90 @Regeneron
Thanks Ricardo!
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Replying to @Bruskolab
Go Holger!
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A big congrats to first-author, Dr. Gerald Coulis! #muscle #immunology #myotwitter
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We collectively establish a spatial atlas of dystrophic muscle that provides profound insight on the regulation of macrophage and stromal interactions during impaired muscle regeneration and fibrosis. Special thanks to my colleagues and collaborators for their contributions.
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Happy to share two recent pubs, one by my lab and a second in collaboration with our colleagues @Regeneron. #muscle #immunology #myotwitter pnas.org/doi/10.1073/pnas.22… science.org/doi/10.1126/scia…

A cellular and molecular spatial atlas of dystrophic muscle | PNAS

Asynchronous skeletal muscle degeneration/regeneration is a hallmark feature of Duchenne muscular dystrophy (DMD); however, traditional -omics tech...

pnas.org
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Armando Villalta retweeted
Claudia Jakubzick@claudjak15 May 2023
Thrilled to share our preprint. Interstitial macs unbiased clustering is due to conserved chemokine expression patterns, resembling T cell biology with cytokines 👇 IM-depleting 🐭showed their major role is orchestrating leukocyte recruitment in TLOs. biorxiv.org/content/10.1101/…
Chemokine expressing IM subsets

ALT Chemokine expressing IM subsets

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Armando Villalta retweeted
Ben Chazaud@BenChazaud8 May 2023
Happy to share our last work in collaboration with Jeff Dilworth @EpigeneticsYOW on the epigenetic-regulated loss of myogenic identity in DMD muscle stem cells. All made with human muscle stem cells! biorxiv.org/content/10.1101/…

Epigenetic control of myogenic identity of human muscle stem cells in Duchenne Muscular Dystrophy

In Duchenne Muscular Dystrophy (DMD), the absence of the subsarcolemmal dystrophin protein leads to repeated myofiber damages inducing cycles of muscle regeneration that is driven by muscle stem...

biorxiv.org
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Replying to @shlotfipour
Good luck. I know you’ll crush it.
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Replying to @shlotfipour
battle wounds!
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Pre-print of our latest work. biorxiv.org/content/10.1101/…

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal...

The monocytic/macrophage system is essential for skeletal muscle homeostasis, but its dysregulation contributes to the pathogenesis of muscle degenerative disorders. Despite our increasing knowledge...

biorxiv.org
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