@YentliSA

@UPennMDPhD trainee #Doubledoc👩🏻‍⚕️👩🏻‍🔬hoping to eliminate #ALS & #FTD before these diseases eliminate me. 🔗 https://xitter.cf/t.co/7Gf3yWwpyP 🌎 Life is beautiful ✨

 Philadelphia, PA
linkedin.com/in/yentli-soto-albrecht-2024-phd/
Joined December 2019
  • Tweets709
  • Following365
  • Followers541
55Media
Honored to share my story on a big stage @brkthroughprize , to grow awareness and fight ASL/FTD for myself & others
Breakthrough
@brkthroughprizeApr 22
Singer, songwriter, and EGOT winner John Legend, and Co-Founder and CEO of Google DeepMind Demis Hassabis introduced a powerful story of science and humanity, highlighting the search for genetic causes behind neurodegenerative diseases like ALS and frontotemporal dementia. They welcomed Yentli Soto Albrecht, who shared her personal journey after inheriting a genetic mutation linked to both conditions. Her story underscored the impact of discoveries by 2026 Breakthrough Prize in Life Sciences laureates Rosa Rademakers and Bryan Traynor, whose work revealed the connection between these diseases—offering not only understanding, but a path toward future treatments and hope for generations to come. Watch the show premiere April 26 at 3 pm EDT at youtube.com/breakthroughpriz…
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabAug 14
Rising to the Challenge: One Student’s Journey on a Reimagined Path: thedish-pennbgs.squarespace.…
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Evan Noch@EvanNochJul 18
Great catching up with @YentliSA at @UTSWBrain Physician-Scientist Symposium today! 🧠
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabJun 18
PennMed Trainees Against ALS/FTD White Dog Cafe happy hour!
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🧠🤖 Can AI help us find a cure for ALS? @YentliSA explains how researchers are using AI to identify new drug targets by finding patterns hidden in massive biological datasets. 🎙️ Full interview: youtu.be/LtSxpWO5iV4
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5 years ago, I asked Doug Wallace, "What happens if we infect cells lacking mito DNA with SARS-CoV-2? Can the virus make more virus (replicate)?" We're floored by the answer & excited to share our team effort across @ChildrensPhila & @neidl @BU_Tweets with you!
ShorterLab@ShorterLabJun 3
Mitochondrial OXPHOS restricts SARS-CoV-2 replication | Science Advances, exciting work by @YentliSA et al. science.org/doi/10.1126/scia…

Mitochondrial OXPHOS restricts SARS-CoV-2 replication

The balance between OXPHOS and glycolysis dictates SARS-CoV-2 replication, where OXPHOS is antiviral.

science.org
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabMay 7
We are thrilled to announce that Penn Medicine Against ALS is one of 20 international teams to win a #LongitudePrizeOnALS Discovery Award! 🎉: challengeworks.org/news/anno… @mndassoc @Challenge_Works @PennMedicine
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabMay 7
Replying to @ShorterLab @mndassoc @Challenge_Works @YentliSA @BB_UPenn @TNRLab @AlessandraChesi @ophirshalem @YosephBarash @delafuentelab @longitude_prize
Thank you Aurora Golden-Appleton, MS2, of PennMed Trainees Against ALS/FTD & Carmen Lennon, for the amazing pictures!
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabMay 7
Replying to @ShorterLab @mndassoc @Challenge_Works @YentliSA @BB_UPenn @TNRLab @AlessandraChesi @ophirshalem @YosephBarash @delafuentelab
To drive our discovery, we will now have access to the largest ALS patient dataset of its kind, including genomic sequences of 9,000 patients and multi-omics data for over 2,000 cases. @longitude_prize
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabMay 7
Replying to @ShorterLab @mndassoc @Challenge_Works @YentliSA @BB_UPenn @TNRLab @AlessandraChesi @ophirshalem @YosephBarash @delafuentelab
across sporadic and genetic forms of ALS. By unifying genetic, splicing, and network-level data into a single subtype-aware framework, the team will deliver a rigorously prioritized shortlist of therapeutic targets ready for rapid validation and translation into new treatments.
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabMay 7
Replying to @ShorterLab @mndassoc @Challenge_Works @YentliSA @BB_UPenn @TNRLab @AlessandraChesi @ophirshalem @YosephBarash @delafuentelab
Penn Medicine Against ALS is deploying an integrated AI ecosystem — including tissue-specific large language models for RNA splicing and polyadenylation, and deep learning models of RNA-binding protein networks — to map precisely how TDP-43 drives gene dysregulation...
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Yentli Soto Albrecht retweeted
ShorterLab@ShorterLabMay 7
Replying to @ShorterLab @mndassoc @Challenge_Works
Nucleated by the inspirational @YentliSA Penn Medicine Against ALS is a collaboration led by @shorterlab of @BB_UPenn, in partnership with Defne Amado, MD, PhD, Corey McMillan, PhD, @TNRLab, Michael Guo, MD, PhD, @AlessandraChesi, @ophirshalem, @YosephBarash, and @delafuentelab!
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Breakthrough
@brkthroughprizeApr 26
2026 Breakthrough Prize Ceremony xitter.cf/i/broadcasts/1YGNrZOPN…
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Penn Medicine
@PennMedicineApr 18
Major milestone for genomic medicine: Penn’s Jean Bennett and Albert Maguire, with @childrensphila's Katherine High, have received the @Breakthrough Prize in Life Sciences for their pioneering work treating inherited blindness. spr.ly/6016B675Tp
Jean Bennett, MD, PhD, Albert Maguire, MD, and Katherine High, MD, smiling and wearing their Breakthrough Prize medals around their necks

ALT Jean Bennett, MD, PhD, Albert Maguire, MD, and Katherine High, MD, smiling and wearing their Breakthrough Prize medals around their necks

Jean Bennett, MD, PhD, Albert Maguire, MD, and Katherine High, MD, posing on the Breakthrough Prize red carpet

ALT Jean Bennett, MD, PhD, Albert Maguire, MD, and Katherine High, MD, posing on the Breakthrough Prize red carpet

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Yentli Soto Albrecht retweeted
Breakthrough
@brkthroughprizeApr 22
Singer, songwriter, and EGOT winner John Legend, and Co-Founder and CEO of Google DeepMind Demis Hassabis introduced a powerful story of science and humanity, highlighting the search for genetic causes behind neurodegenerative diseases like ALS and frontotemporal dementia. They welcomed Yentli Soto Albrecht, who shared her personal journey after inheriting a genetic mutation linked to both conditions. Her story underscored the impact of discoveries by 2026 Breakthrough Prize in Life Sciences laureates Rosa Rademakers and Bryan Traynor, whose work revealed the connection between these diseases—offering not only understanding, but a path toward future treatments and hope for generations to come. Watch the show premiere April 26 at 3 pm EDT at youtube.com/breakthroughpriz…
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Yentli Soto Albrecht retweeted
Scientific American
@sciamApr 24
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) can have the same genetic cause, a discovery that won two neurogeneticists a portion of the 2026 Breakthrough Prize in Life Sciences spklr.io/6014EKn6q

How geneticists uncovered a common root of two neurological diseases

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) can have the same genetic cause, a discovery that won two neurogeneticists a portion of the 2026 Breakthrough Prize in Life...

scientificamerican.com
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It was an honor to speak at the @brkthroughprize last week and introduce the two scientists who discovered my genetic mutation, the C9 repeat expansion: Rosa Rademakers and Bryan Traynor. Let’s cure ALS and FTD!
Breakthrough
@brkthroughprizeApr 22
Singer, songwriter, and EGOT winner John Legend, and Co-Founder and CEO of Google DeepMind Demis Hassabis introduced a powerful story of science and humanity, highlighting the search for genetic causes behind neurodegenerative diseases like ALS and frontotemporal dementia. They welcomed Yentli Soto Albrecht, who shared her personal journey after inheriting a genetic mutation linked to both conditions. Her story underscored the impact of discoveries by 2026 Breakthrough Prize in Life Sciences laureates Rosa Rademakers and Bryan Traynor, whose work revealed the connection between these diseases—offering not only understanding, but a path toward future treatments and hope for generations to come. Watch the show premiere April 26 at 3 pm EDT at youtube.com/breakthroughpriz…
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Yentli Soto Albrecht retweeted
Penn Medicine CSO@PennMedCSOApr 22
.@PennMedicine student @YentliSA inherited a genetic mutation that causes #ALS. She recently spoke with @PhillyInquirer about her work to tackle gaps in research on the condition in the hopes of finding a cure ft. Defne Amado (@PennNeurology) tinyurl.com/34fytcxr
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Yentli Soto Albrecht retweeted
The Philadelphia Inquirer
@PhillyInquirerApr 7
A Penn medical student has a 95% chance of developing a fatal neurodegenerative disease. She wants to find a cure before that happens. ebx.sh/74IPwo

A Penn medical student has a 95% chance of developing a fatal neurodegenerative disease. She wants...

Yentli Soto Albrecht inherited a genetic cause of ALS. She's now managing eleven projects that together aim to tackle gaps in research on the condition, before it likely affects her.

ebx.sh
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#ADPD2026: Day 5 Highlights, Reflections, and Excitement from Copenhagen! 🌍✨ In the last recap video, @YentliSA, PhD, an MD-PhD student at the University of Pennsylvania, and @iampriyasuman, Ph.D., a neuroscience candidate at @uOttawa Research Institute, joined us to share highlights from the conference and reflect on their experience in Copenhagen. From inspiring sessions to meaningful discussions, their insights truly capture the essence of this year’s event! 🎥 Watch the full recap to hear their takeaways, personal experiences, and the exciting future of neurodegenerative disease research. ✨ Thank you to everyone who joined us in Copenhagen and online - see you next year! #ResearchInnovation #ScientificCommunity #neuroinflammation – at Bulgaria
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