İstanbul, Türkiye
Joined April 2009
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MSCA Postdoctoral Fellowships 2026 hosting offer - at the Eda Yildirim Lab of Koc University - MBG, Türkiye euraxess.ec.europa.eu/jobs/h…
Eda Yildirim retweeted
How are mitotic chromosomes built? 🏗️ Our Review @TrendsGenetics revisits the classical chromosome scaffold model and connects it to condensins, topoIIα, and physical forces. We propose interphase chromatin domains as “building blocks”🧩of chromosomes:
authors.elsevier.com/a/1nmwr…
Eda Yildirim retweeted
A personal message from 2022 chemistry laureate Carolyn Bertozzi to all young researchers on why to aspire to a career in science:
”I would want to share with them how a life in science is incredibly rewarding. It is rewarding because it is creative."
#NobelPrize
ALT Portrait of Carolyn Bertozzi, Nobel Prize laureate chemistry, with a quote: "Knowledge stays with us forever and becomes the foundation for next generations."
Enjoyed a fun celeberatory dinner with my lab today! Congrats to my talented students Ali and Salwa graduating at the top of their class from Mol Bio & Genetics Dept @KocSciences. Both received @kocuniversity presedential fellowships and joined my lab as graduate students. 🎉🥂 – at Sarıyer, İstanbul
Eda Yildirim retweeted
Introns have a hidden regulatory role! 🧬🎉
Delighted to share our latest paper showing that inefficiently spliced introns and spliceosomal proteins direct RNA methylation, engaging RNAi to silence retrotransposons and regulate gene expression
nature.com/articles/s41467-0…
🤖 Made with AI
Eda Yildirim retweeted
Cells control gene expression through combinatorial interactions between readers, writers, and erasers of chromatin marks, but most epigenetic editing tools rely on a single effector in isolation.
The @pdhsu & @SKonermann labs developed COMBINE: the first platform to systematically test those combinations at scale, screening 50,000+ effector pairs.
Eda Yildirim retweeted
(1/16) Our 3-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack is out:
Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)?
A: Transient E-P contact (~25-42 nm lasting ~10-20 sec): biorxiv.org/content/10.64898…
Eda Yildirim retweeted
🔥Genomics of aging in @Nature !!🔥
nature.com/articles/s41586-0…
Eda Yildirim retweeted
Finally out in @Cellcellpress!
Proteins with long intrinsically disordered regions (IDRs) are prone to misfolding during protein synthesis.
This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones.
cell.com/cell/fulltext/S0092…
Eda Yildirim retweeted
Exciting breakthrough technology from the lab, now live in @CellCellPress ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!
We were delighted to have Dr. @GabrielNeurohr from ETH Zürich to give an @EMBO Young Investigator Lecture at @KocSciences Mol Bio and Genetics Dept. We enjoyed learning about his lab’s research on nuclear size and senescence.
Eda Yildirim retweeted
Bazı hikayeler tek kişilik değildir.
Bir ODTÜ hikayesinin içinde;
uykusuz geceler, uzun yollar, bekleyişler ve hep sessizce arkada duran bir emek vardır.
Bugün; çocuklarının hayallerine inanan, onların yolculuğuna güç veren
tüm annelerin Anneler Günü kutlu olsun ♥️
Eda Yildirim retweeted
1/ Preprint alert 🚨🚨🚨 How do cells decide where an mRNA should end?
And how is that decision coordinated with splicing and transcription while the RNA is still being made?
Here's what first author @HopeMerens found 👇
Eda Yildirim retweeted
Could the folding of synthetic gene circuits in 3D shape how genes are expressed? Today @ScienceMagazine we report on the role of gene syntax in shaping feedback between transcriptional activity and genome folding for advanced circuit design🧵 (1/n)
Eda Yildirim retweeted
New online! Direct roles of long non-coding RNAs in transcription activation dlvr.it/TSK9MJ
Eda Yildirim retweeted
Nature Human Behaviour から "How to design effective scientific figures" というコメンタリーが出ました🎉参考になれば幸いです！！
nature.com/articles/s41562-0…
@NatureHumBehav
I’m thrilled to announce that my new comment titled “How to design effective scientific figures” is now released from @NatureHumBehav
This provides five keys to make your graphical items attractive 🎨 Hope this is useful for your project!
nature.com/articles/s41562-0…
It was a pleasure to have Prof. @BatuErman visit our Department @KocSciences today. We all enjoyed his MBGE seminar on nanobody development and its applications.
