Nanyang Technological University, School of Biological Sciences, Singapore
Singapore
Joined November 2017
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Zhao-Xun Liang retweeted
Genome editing of phylogenetically distinct bacteria using cross-species retron-mediated recombineering.
nature.com/articles/s41587-0…
Harnessing biosynthetic logic for next-generation ADC payloads - now published in Chemical Society Reviews pubs.rsc.org/en/content/arti…@
We couldn’t have discovered those interesting antimalarial compounds without the help from our wonderful collaborators.
Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides - Candra - Angew Chem Intl Ed - onlinelibrary.wiley.com/doi/…
Zhao-Xun Liang retweeted
What it's all about. 💜🥹
Prof. Joel Mokyr, winner of the @NobelPrize in Economic Sciences, shares a lovely message from a former student.
Functional Characterization of a Diazo-Forming Enzyme in Meroterpenoid Biosynthesis
chemistry-europe.onlinelibra…
Big Thanks to our collaborators @pchaiyen @guanglei_Ma @HoaUSD12345, Profs Li Jian, and Gao YG
An Enzymatic Oxidation Cascade Converts δ-Thiolactone Anthracene to Anthraquinone in the Biosynthesis of Anthraquinone-Fused Enediynes | JACS Au pubs.acs.org/doi/abs/10.1021…
Streptomyces sungeiensis SD3 as a Microbial Chassis for the Heterologous Production of Secondary Metabolites | ACS Synthetic Biology pubs.acs.org/doi/10.1021/acs…
A useful Streptomyces strain from the Johor Strait @zjlow @guanglei_Ma @
Zhao-Xun Liang retweeted
Happy to share our review of cyclic-di-AMP signalling in lactic acid bacteria as part of the @LABsymposiumorg
special edition in @FEMSmicro
Thanks to @HuongPham2021 @Es_Marcellin @ZX_Liang & Yuwei for your contributions and many years of collaboration
academic.oup.com/femsre/arti…
Zhao-Xun Liang retweeted
“resistant #pseudomonas was especially difficult to eradicate” 😱 nytimes.com/2023/04/03/healt…
Zhao-Xun Liang retweeted
Today we're making RF Diffusion, our guided diffusion model for protein design with potential applications in medicine, vaccines & advanced materials, free to use. The software has proven much faster and more capable than prior protein design tools.
bakerlab.org/2023/03/30/rf-d…
Enaminone formation drives the coupling of biosynthetic pathways to generate cyclic lipopeptides chemistry-europe.onlinelibra… @hart
Zhao-Xun Liang retweeted
#Biosynthesis of Tasikamides via Pathway Coupling & Diazonium-Mediated Hydrazone Formation by @guanglei_Ma, H. Candra, L. Mei Pang, J. Xiong, Y. Ding, H. Thi Tran, @ZhenjieLow, H. Ye, M. Liu, J. Zheng, M. Fang, @embb_ntu, @ZX_Liang in @J_A_C_S pubs.acs.org/doi/10.1021/jac…
To our surprise, we found hydrazone can be formed via diazonium-mediated Japp-Klingemann reaction in microbial cells, thanks to the excellent work of @guanglei_Ma, Hart, @hoatran227, @zjlow, Pang LM... and our collaborators Profs Cao Bin and Fang Mingliang
Online NOW | @J_A_C_S
#Biosynthesis of #Tasikamides via Pathway Coupling and Diazonium-Mediated #Hydrazone Formation.
@isciverse @AmerChemSociety
pubs.acs.org/doi/10.1021/jac…
Zhao-Xun Liang retweeted
What drives organization of RNA, DNA, and proteins in the nucleus? In our new paper out @CellCellPress, we show that non-coding RNAs play a central role through a unique RNA-based mechanism. authors.elsevier.com/c/1e132…
Zhao-Xun Liang retweeted
A proof of concept for c-di-GMP phosphodiesterase-activating drugs administered in combination with antibiotics as a viable treatment strategy for otherwise recalcitrant infections
nature.com/articles/s41522-0…
Zhao-Xun Liang retweeted
Understanding biology, and host/pathogen interactions in particular (including #SARSCoV2) without looking at glycan part of proteins is simply not possible. You do not have to take my word for it, check that latest issue of Nature instead... nature.com/articles/d41586-0…
Zhao-Xun Liang retweeted
A historic moment in the world of molecular structural research. #AlphaFold structure predictions for 22 species made freely available by @deepmind, access through @uniprot and @PDBeurope. Learn more at insideuniprot.blogspot.com/
Zhao-Xun Liang retweeted
Very pleased to see that we are ranked 3⃣3⃣ in the world in Biological Sciences by QS @worlduniranking. Awesome work from #ntusbs staff and students. #ntusbs community should be proud about this impressive rise over the years 🚀
Pathway Retrofitting Yields Insights into the Biosynthesis of Anthraquinone-Fused Enediynes pubs.acs.org/doi/10.1021/jac…
@hoatran227 @zjlow
