Scott Zamvil (@ZamvilScott) profile picture

Scott Zamvil

@ZamvilScott
Joined May 2013
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This case highlights an unusual presentation of severe MOGAD, emphasizes the potential benefit of plasma exchanges in severe MOGAD cases refractory to steroid treatment, and demonstrates how assessment of CSF IL-6 may help guide treatment decisions: bit.ly/3w5SUD5
Brain MRI at presentation demonstrates small T2-FLAIR hyperintense lesions of the right frontal subcortical white matter and right lateral pons with mild enhancement. Thoracic spine MRI demonstrates T2 hyperintensity at T2-3 and enhancement involving the ventral cord at T2-3 and T6-7.

ALT Brain MRI at presentation demonstrates small T2-FLAIR hyperintense lesions of the right frontal subcortical white matter and right lateral pons with mild enhancement. Thoracic spine MRI demonstrates T2 hyperintensity at T2-3 and enhancement involving the ventral cord at T2-3 and T6-7.

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Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis pnas.org/content/early/2019/…
Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis | PNAS

Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis | PNAS

CD8+ T cells are believed to play an important role in multiple sclerosis (MS), yet their role in MS pathogenesis remains poorly defined. Although ...

pnas.org
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How do B cells contribute to CNS diseases? Read this new Review by Joseph Sabatino Jr, Anne-Katrin Pröbstel (@akproebstel) and Scott Zamvil #Bcells go.nature.com/2KciBXs
Image from Nature Rev Neurosci (@NatRevNeurosci)
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How do B cells contribute to CNS diseases? Read this new Review by Joseph Sabatino Jr, Anne-Katrin Pröbstel (@akproebstel) and Scott Zamvil #Bcells go.nature.com/2KciBXs
Image from Nature Rev Neurosci (@NatRevNeurosci)
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