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Compressing biology to develop the next generation of therapeutics

Seattle, WA
Joined October 2023
Photo by ZipBio (@ZipBio_Inc)
Congratulations to Dr. David Baker on the Nobel Prize in Chemistry! We are proud to celebrate Dr. Baker’s groundbreaking contributions to protein design, which have transformed modern medicine. youtube.com/watch?v=6-A4dUow…
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Dr. Baker was the mentor and doctoral supervisor of our CTO, @Arielbs100. Our work continues to be deeply influenced by Dr. Baker’s vision, driving us to push the boundaries of protein design to tackle some of the most complex challenges in medicine.
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We are excited to contribute to the scientific revolution Dr. Baker has helped shape and look forward to advancing the future of drug development.
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Founded by @roee_farber, @Arielbs100, @ozelichov and Ori Hassin our COMPACT platform compresses complex biological structures into smaller, more efficient de novo-designed proteins that retain full functionality, optimizing delivery and therapeutic effectiveness.
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We're backed by NFX and MoreVC and are expanding our team in Seattle, Boston and Tel Aviv.
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Here's an interesting use of AI in drug design: making compact proteins. @ZipBio_Inc is shaving off the unimportant parts of proteins and using generative AI to fill in a backbone that holds the molecule together. Read more in my exclusive for @endpts: endpts.com/exclusive-zipbio-…
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The February issue, with a focus on protein engineering, is live nature.com/nbt/volumes/42/is… Our cover shows the three data types key to machine learning for functional protein design: structure, sequence and labels, from a Review by Notin et al. go.nature.com/49EPi9x
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A new paper by our co-founder and CTO @Arielbs100 is now out in @CellCellPress
It's so satisfying to see our work in print! We showcase computer designed #protein #biomaterials engaging cells with molecular precision to decipher one of the most fundamental and yet elusive determinants of cell division process. Huge POC for the future of #synthetic_biology!
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