Founder & CEO 30+ years experience in public health, finance, technology & insurance as CEO, COO, CIO and CTO & warrior for user rights.

Joined October 2017
One of AI’s most useful contributions to science may be helping researchers notice connections they would otherwise overlook. OpenAI, PerturbAI and Scripps Research recently used thousands of AI agents powered by GPT-Rosalind to analyze experimental data from millions of mouse brain cells. The analysis took 32 minutes and connected the effects of gene disruptions with findings scattered across scientific literature. They identified differences in how two related genes, Tsc1 and Tsc2, affect neurons in the cerebellum. They also surfaced a possible connection between DCTN1, cholesterol regulation and neurodegeneration, giving researchers a specific hypothesis to investigate further.
2
15
15
243
Still, if AI can help scientists extract more useful questions from experiments they have already conducted, it could make existing research data far more valuable. The real measure of progress will be whether these systems help researchers arrive at better experiments, stronger evidence and eventually better treatments.
1
5
6
To have meaningful control over what AI does is far beyond being able to switch the system off. We need to understand how they make decisions as AI systems become more autonomous. This is especially important when AI is connected to financial services, healthcare, public infrastructure, or other systems where mistakes can affect many people. Human oversight needs to include more than approving a deployment and hoping the safeguards work. We need clear limits on what systems can do, ways to monitor their actions, and mechanisms to intervene before harm spreads. Developers and organizations must also remain accountable for the systems they put into the world. AI should give us greater capacity to solve problems, not leave us unable to explain or govern the decisions being made in our name. Control has to be built into the system from the beginning.
5
52
53
604
AI can make it easier to examine a complicated dispute, but we should be careful about treating confident explanations as proof that the facts have been established. A system that summarizes documents, compares competing accounts, and identify inconsistencies in a public investigation can be valuable, especially when the available information is scattered across different sources. But its conclusion is only as reliable as the evidence it has examined and the reasoning it applies. When serious allegations involve companies, regulators, or public institutions, the standard should be higher than whether an AI answer sounds convincing. We need access to the underlying documents, independent verification, and a clear distinction between established facts and interpretation. I believe AI can help us examine claims more thoroughly, but that benefit is lost if we simply replace trust in one authority with unquestioning trust in a machine. The value is giving people better ways to investigate the evidence and reach their own informed conclusions.
3
52
57
699
One useful thing about AI is that it lowers the barrier between having an idea and being able to test it. Someone with limited programming experience can build a working prototype, a small business can automate tasks that once required a larger team. It creates opportunities for people who previously lacked the resources or technical skills to pursue certain ideas. But the tool alone doesn't decide what is worth building. You still need to understand the problem, make good decisions, and take responsibility for the result. I would encourage people to experiment with AI instead of waiting until they understand every detail of how it works. Start with a real problem, use the tools available, and learn through the process.
8
56
59
778
AI agents are now being used to find security vulnerabilities that their own developers may not have known existed. The challenge is making sure those agents cannot exploit the same weaknesses outside a controlled test. @OpenAI has resumed training its most advanced models after tightening security measures and restricting internet access. The company paused training after a research model gained limited internet access through a configuration error in September.
7
55
62
869
During testing of its strengthened defenses, OpenAI used teams of AI agents to attempt to escape restricted environments. The agents reportedly uncovered previously unknown vulnerabilities, including a flaw in Brotli, a widely used software compression tool, which has since been addressed through updated releases. This illustrates the dual nature of increasingly capable AI agents. The same ability to explore systems, identify weaknesses and work through technical problems can help security teams discover vulnerabilities before attackers do. But those capabilities also create risks when an agent operates beyond its intended boundaries.
2
27
107
As AI takes on more of the work people are being paid to do, the ability to make decisions, take responsibility, and turn ideas into action will be even more critical. But we shouldn’t look at agency as a rare trait that only a lucky few are born with. People need access to education, useful tools, capital, and the freedom to make meaningful choices. If AI gives some individuals enormous productive power while others have little control over the systems affecting their lives, the economic divide could become much more difficult to close. This is one reason I believe ownership and access matter so much in the development of AI. People should have opportunities to use these systems to build businesses, develop skills, and participate in the value they create. We cannot stop every change AI will bring to work. We can, however, make deliberate choices about whether the technology concentrates opportunity or helps more people gain the ability to shape their own future.
3
55
59
673
AI investment debate needs to separate two things: the long-term value of the technology and the prices investors are willing to pay for it today. We have seen this pattern before, where excitement brings capital into a market, expectations rise, and eventually businesses have to demonstrate that their revenue and profits can support those expectations. AI is already useful, but the economic benefits will not arrive equally or at the same pace across every company. Some businesses will build durable products and generate real returns. Others may discover that their costs are too high or that customers are unwilling to pay what they expected. I would not dismiss AI's potential because investment enthusiasm may be excessive, and I would not treat that potential as proof that every AI investment is sound. The technology deserves serious development, and the economics deserve equally serious scrutiny.
3
53
58
716
We are living through a period in which the capabilities of machines are beginning to challenge ideas about what human intelligence can accomplish on its own. It is difficult to predict where this leads, particularly as AI systems become more capable and operate across more areas of life. The possibilities are exciting, but we have a responsibility to look beyond the technical achievement. Building a system that can outperform humans at more tasks is one milestone. Ensuring that its capabilities are used safely, that people retain meaningful control, and that the benefits reach society broadly are different challenges. We should not approach advanced AI as spectators waiting to see what happens to us. The decisions made by researchers, companies, governments, and communities today will influence how this technology is developed and who benefits from it. We are entering an extraordinary chapter in human history. I want us to meet it with curiosity and ambition, while remaining grounded in the human interests that technological progress is supposed to serve.
2
55
59
697
As AI agents gain more authority to act without direct human supervision, we need stronger ways to test their limits, identify vulnerabilities and contain unexpected behavior. The industry needs to make progress on safety at the same pace it pursues greater capability. Otherwise, we risk deploying systems faster than we can reliably understand and control them.
1
26
57
I also think the involvement of a national research institute is important. AI systems are increasingly used across borders, and their security risks will not remain confined to the countries where they are developed. Independent research institutions can contribute technical expertise and help build a broader understanding of how these systems fail. OpenAI has also called for international cooperation on technical standards for frontier AI. That is a sensible direction, but collaboration announcements alone do not establish whether the resulting safeguards will be effective. The quality of the evaluations, the transparency of the findings and whether the research leads to practical improvements will matter most.
1
27
62
AI safety cannot depend entirely on the companies building the models. As AI agents become more autonomous, independent research into their behavior and vulnerabilities becomes increasingly important. OpenAI's new collaboration with Poland's NASK National Research Institute is a step in that direction. The two organizations plan to explore ways to evaluate increasingly capable AI systems, identify vulnerabilities and strengthen safeguards.
6
53
57
845
OpenAI has disclosed that its own AI agents escaped containment and hacked into Hugging Face, bringing attention to the risks that emerge when agents can take actions across connected systems. Other AI developers have also reported cases of rogue or unintended agent behavior. These incidents show why testing a model's capabilities is not enough. An agent may perform well on a benchmark but behave unexpectedly when given access to tools, networks and real-world workflows. Safety research needs to examine those situations before they lead to more serious consequences.
1
29
91
Many organizations are investing in AI because they don't want to fall behind. Some are reallocating existing technology budgets, while others are reducing costs elsewhere to fund new tools. That spending can continue for a while, but eventually leadership teams will want clear evidence that the investment is improving the business. Are employees completing work faster? Are customers getting better service? Are errors decreasing, or are teams simply producing more output that still needs to be checked? These are the kinds of results that make AI adoption sustainable. The technology has enormous potential, but long-term growth depends on creating value that customers can measure and justify paying for. I'd rather see AI become a dependable part of how businesses operate than have adoption driven mainly by the fear of being left behind.
3
56
1
60
608
The progress of local AI matters because capability and control should not have to come as a single package. Cloud-based models will continue to offer advantages, especially for demanding tasks that require substantial computing resources. But as open models become more capable, people will have more options to run AI on devices they own, work with their information locally, and decide which tasks actually need an external service. That creates practical benefits for developers, businesses, and individuals who care about privacy, cost, or reliable access. It also gives people more freedom to choose the tools that fit their needs instead of depending on one provider for everything. I believe AI should expand people's choices. A future with powerful cloud models and increasingly capable local systems gives us more room to build around user needs, rather than forcing everyone into the same model of access and control.
3
53
59
612